The Epigenomics of Pituitary Adenoma

The Epigenomic Landscape of Pituitary Adenomas Reveals Specific Alterations and Differentiates Among Acromegaly, Cushing's Disease and Endocrine-Inactive Subtypes

(2018) Matthew P. Salomon et al.   CLINICAL CANCER RESEARCH

Genomic Alterations in Sporadic Pituitary Tumors

(2018) Wenya Linda Bi et al.   Current Neurology and Neuroscience Reports

Histone citrullination represses miRNA expression resulting in increased oncogene mRNAs in somatolactotrope cells

(2018) Stanley B. DeVore et al.   MOLECULAR AND CELLULAR BIOLOGY

DNA methylation-based classification of central nervous system tumours

(2018) David Capper et al.   NATURE

Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas

(2018) Isabella P. P. Grande et al.   Pituitary

Overexpression of DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) And DNA (Cytosine-5)-Methyltransferase 3A (DNMT3A) Is Associated with Aggressive Behavior and Hypermethylation of Tumor Suppressor Genes in Human Pituitary Adenomas

(2018) Hou-Shi Ma et al.   MEDICAL SCIENCE MONITOR

Temozolomide and Pituitary Tumors: Current Understanding, Unresolved Issues, and Future Directions

(2018) Luis V. Syro et al.   Frontiers in Endocrinology

Identification of recurrent USP48 and BRAF mutations in Cushing’s disease

(2018) Jianhua Chen et al.   Nature Communications

From pituitary adenoma to pituitary neuroendocrine tumor (PitNET): an International Pituitary Pathology Club proposal

(2017) S L Asa et al.   ENDOCRINE-RELATED CANCER

European Society of Endocrinology Clinical Practice Guidelines for the management of aggressive pituitary tumours and carcinomas

(2017) Gerald Raverot et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

MicroRNA-524-5p Functions as a Tumor Suppressor in a Human Pituitary Tumor-Derived Cell Line

(2017) Wang Zhen et al.   HORMONE AND METABOLIC RESEARCH

DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis

(2017) Felix Sahm et al.   LANCET ONCOLOGY

MicroRNAs in pituitary tumors

(2017) Anne Wierinckx et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Long non-coding RNA C5orf66-AS1 is downregulated in pituitary null cell adenomas and is associated with their invasiveness

(2017) Guoqiang Yu et al.   ONCOLOGY REPORTS

RIZ1 and histone methylation status in pituitary adenomas

(2017) Yake Xue et al.   TUMOR BIOLOGY

Landscape of Genomic Alterations in Pituitary Adenomas

(2016) Wenya Linda Bi et al.   CLINICAL CANCER RESEARCH

NG2 targets tumorigenic Rb inactivation in Pit1-lineage pituitary cells

(2016) Toru Tateno et al.   ENDOCRINE-RELATED CANCER

Differential DNA methylome profiling of nonfunctioning pituitary adenomas suggesting tumour invasion is correlated with cell adhesion

(2016) Ye Gu et al.   JOURNAL OF NEURO-ONCOLOGY

MMP-14 and TGFβ-1 methylation in pituitary adenomas

(2016) Kornelija Ruskyte et al.   Oncology Letters

Genome-wide analysis of differentially expressed lncRNAs and mRNAs in primary gonadotrophin adenomas by RNA-seq

(2016) Jiye Li et al.   Oncotarget

hTERT promoter methylation in pituitary adenomas

(2015) Michaela Köchling et al.   Brain Tumor Pathology

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

(2015) Kristian W. Pajtler et al.   CANCER CELL

HMGA1-pseudogene expression is induced in human pituitary tumors

(2015) Francesco Esposito et al.   CELL CYCLE

Recurrent gain-of-function USP8 mutations in Cushing's disease

(2015) Zeng-Yi Ma et al.   CELL RESEARCH

Landscape of somatic mutations in sporadic GH-secreting pituitary adenomas

(2015) Cristina L Ronchi et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

Common variants at 10p12.31, 10q21.1 and 13q12.13 are associated with sporadic pituitary adenoma

(2015) Zhao Ye et al.   NATURE GENETICS

Gene and protein expression in pituitary corticotroph adenomas: a systematic review of the literature

(2015) Justin Seltzer et al.   Neurosurgical Focus

Epidrug mediated re-expression of miRNA targeting the HMGA transcripts in pituitary cells

(2015) Mark O. Kitchen et al.   Pituitary

HOXB1 Is a Tumor Suppressor Gene Regulated by miR-3175 in Glioma

(2015) Liang Han et al.   PLoS One

In1-ghrelin splicing variant is overexpressed in pituitary adenomas and increases their aggressive features

(2015) Alejandro Ibáñez-Costa et al.   Scientific Reports

Descriptive epidemiology of pituitary tumors in the United States, 2004–2009

(2014) Haley Gittleman et al.   JOURNAL OF NEUROSURGERY

Mutations in the deubiquitinase gene USP8 cause Cushing's disease

(2014) Martin Reincke et al.   NATURE GENETICS

Aggressive pituitary adenomas—diagnosis and emerging treatments

(2014) Antonio Di Ieva et al.   Nature Reviews Endocrinology

Genetic mutations in sporadic pituitary adenomas—what to screen for?

(2014) Anne-Lise Lecoq et al.   Nature Reviews Endocrinology

Implications of MGMT methylation status in pituitary adenoma

(2014) Sneha Arya et al.   PATHOLOGY RESEARCH AND PRACTICE

A Pilot Genome-Scale Profiling of DNA Methylation in Sporadic Pituitary Macroadenomas: Association with Tumor Invasion and Histopathological Subtype

(2014) Chao Ling et al.   PLoS One

A new prognostic clinicopathological classification of pituitary adenomas: a multicentric case–control study of 410 patients with 8 years post-operative follow-up

(2013) Jacqueline Trouillas et al.   ACTA NEUROPATHOLOGICA

Preincubation of Pituitary Tumor Cells With the Epidrugs Zebularine and Trichostatin A Are Permissive for Retinoic Acid-Augmented Expression of theBMP-4andD2RGenes

(2013) Kiren Yacqub-Usman et al.   ENDOCRINOLOGY

Quantitative, genome-wide analysis of the DNA methylome in sporadic pituitary adenomas

(2012) Cuong V Duong et al.   ENDOCRINE-RELATED CANCER

RhoD regulates cytoskeletal dynamics via the actin nucleation–promoting factor WASp homologue associated with actin Golgi membranes and microtubules

(2012) Annica K. B. Gad et al.   MOLECULAR BIOLOGY OF THE CELL

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Targeting Epigenetic Readers in Cancer

(2012) Mark A. Dawson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

MGMT promoter methylation and immunoexpression in aggressive pituitary adenomas and carcinomas

(2011) Fateme Salehi et al.   JOURNAL OF NEURO-ONCOLOGY

Histone Acetylation Patterns of Typical and Atypical Pituitary Adenomas Indicate Epigenetic Shift of these Tumours

(2011) A. Ebrahimi et al.   JOURNAL OF NEUROENDOCRINOLOGY

Pathogenesis of pituitary tumors

(2011) Shlomo Melmed   Nature Reviews Endocrinology

Downregulation of HMGA-targeting microRNAs has a critical role in human pituitary tumorigenesis

(2011) D Palmieri et al.   ONCOGENE

Differential gene expression profiles of invasive and non-invasive non-functioning pituitary adenomas based on microarray analysis

(2010) Françoise Galland et al.   ENDOCRINE-RELATED CANCER

Incidence of Pituitary Adenomas in Northern Finland in 1992–2007

(2010) Antti Raappana et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Prevalence of pituitary adenomas: a community-based, cross-sectional study in Banbury (Oxfordshire, UK)

(2009) Alberto Fernandez et al.   CLINICAL ENDOCRINOLOGY

Expression of p18INK4C is Down-regulated in Human Pituitary Adenomas

(2009) Md. Golam Hossain et al.   ENDOCRINE PATHOLOGY

Histone acetyltransferase p300 regulates the expression of human pituitary tumor transforming gene (hPTTG)

(2009) Tian Li et al.   Journal of Genetics and Genomics

DNA hypomethylation in cancer cells

(2009) Melanie Ehrlich   Epigenomics

Frequent loss of theCDKN2C(p18INK4c) gene product in pituitary adenomas

(2008) Matthias Kirsch et al.   GENES CHROMOSOMES & CANCER

Deoxyribonucleic Acid Methyltransferase 3B Promotes Epigenetic Silencing through Histone 3 Chromatin Modifications in Pituitary Cells

(2008) Xuegong Zhu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Molecular pathogenesis of human prolactinomas identified by gene expression profiling, RT-qPCR, and proteomic analyses

(2008) Chheng-Orn Evans et al.   Pituitary