Molecular and clinical characterization of CD163 expression via large-scale analysis in glioma

Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti–PD-1 treatment

(2018) Elisa Peranzoni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CSF1R + Macrophages Sustain Pancreatic Tumor Growth through T Cell Suppression and Maintenance of Key Gene Programs that Define the Squamous Subtype

(2018) Juliana B. Candido et al.   Cell Reports

Tumor-associated macrophages: from basic research to clinical application

(2017) Li Yang et al.   Journal of Hematology & Oncology

The contribution of tumor-associated macrophages in glioma neo-angiogenesis and implications for anti-angiogenic strategies

(2017) Changbin Zhu et al.   NEURO-ONCOLOGY

Expression of iNOS, CD163 and ARG-1 taken as M1 and M2 markers of microglial polarization in human glioblastoma and the surrounding normal parenchyma

(2017) L. Lisi et al.   NEUROSCIENCE LETTERS

Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth

(2017) Yu Shi et al.   Nature Communications

Crosstalk between M2 macrophages and glioma stem cells

(2017) Leora M. Nusblat et al.   CELLULAR ONCOLOGY

CD163 as a novel target gene of STAT3 is a potential therapeutic target for gastric cancer

(2017) Zhenguo Cheng et al.   Oncotarget

Cancer-associated fibroblasts promote M2 polarization of macrophages in pancreatic ductal adenocarcinoma

(2017) Aibin Zhang et al.   Cancer Medicine

Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy

(2017) Michael A. Cannarile et al.   Journal for ImmunoTherapy of Cancer

CD163+CD204+ tumor-associated macrophages contribute to T cell regulation via interleukin-10 and PD-L1 production in oral squamous cell carcinoma

(2017) Keigo Kubota et al.   Scientific Reports

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

CD163 + M2-type tumor-associated macrophage support the suppression of tumor-infiltrating T cells in osteosarcoma

(2016) Qinglin Han et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

New insights into the multidimensional concept of macrophage ontogeny, activation and function

(2016) Florent Ginhoux et al.   NATURE IMMUNOLOGY

The New Role of CD163 in the Differentiation of Bone Marrow Stromal Cells into Vascular Endothelial-Like Cells

(2016) Wei Lu et al.   Stem Cells International

Regulation of myeloid cells by activated T cells determines the efficacy of PD-1 blockade

(2016) Nina Eissler et al.   OncoImmunology

CD163+CD14+ macrophages, a potential immune biomarker for malignant pleural effusion

(2015) Fei Wang et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Alternatively activated microglia and macrophages in the central nervous system

(2015) Rafael Franco et al.   PROGRESS IN NEUROBIOLOGY

CD163+ tumor-associated macrophage is a prognostic biomarker and is associated with therapeutic effect on malignant pleural effusion of lung cancer patients

(2015) Li Yang et al.   Oncotarget

Engineering strategies to mimic the glioblastoma microenvironment

(2014) Andrew Rape et al.   ADVANCED DRUG DELIVERY REVIEWS

Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy

(2014) Carola H. Ries et al.   CANCER CELL

CSF1/CSF1R Blockade Reprograms Tumor-Infiltrating Macrophages and Improves Response to T-cell Checkpoint Immunotherapy in Pancreatic Cancer Models

(2014) Y. Zhu et al.   CANCER RESEARCH

High density of CD68+/CD163+ tumour-associated macrophages (M2-TAM) at diagnosis is significantly correlated to unfavorable prognostic factors and to poor clinical outcomes in patients with diffuse large B-cell lymphoma

(2014) Francesco Marchesi et al.   HEMATOLOGICAL ONCOLOGY

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Macrophage phenotypes in atherosclerosis

(2014) Sophie Colin et al.   IMMUNOLOGICAL REVIEWS

CD163 Expression Was Associated with Angiogenesis and Shortened Survival in Patients with Uniformly Treated Classical Hodgkin Lymphoma

(2014) Young Wha Koh et al.   PLoS One

Glioma Grade Is Associated with the Accumulation and Activity of Cells Bearing M2 Monocyte Markers

(2013) M. Prosniak et al.   CLINICAL CANCER RESEARCH

Mixed-polarization phenotype of ascites-associated macrophages in human ovarian carcinoma: Correlation of CD163 expression, cytokine levels and early relapse

(2013) Silke Reinartz et al.   INTERNATIONAL JOURNAL OF CANCER

Therapeutically reeducating macrophages to treat GBM

(2013) Christopher Garris et al.   NATURE MEDICINE

Increase in tumor-associated macrophages after antiangiogenic therapy is associated with poor survival among patients with recurrent glioblastoma

(2013) C. Lu-Emerson et al.   NEURO-ONCOLOGY

Inferring tumour purity and stromal and immune cell admixture from expression data

(2013) Kosuke Yoshihara et al.   Nature Communications

Targeting the Hemoglobin Scavenger receptor CD163 in Macrophages Highly Increases the Anti-inflammatory Potency of Dexamethasone

(2012) Jonas H Graversen et al.   MOLECULAR THERAPY

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Scavenger receptor CD163, a Jack-of-all-trades and potential target for cell-directed therapy

(2010) Hanne Van Gorp et al.   MOLECULAR IMMUNOLOGY

The CD163-expressing macrophages recognize and internalize TWEAK

(2009) Juan A. Moreno et al.   ATHEROSCLEROSIS

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

The macrophage scavenger receptor CD163 functions as an innate immune sensor for bacteria

(2008) B. O. Fabriek et al.   BLOOD

Immunotherapy of malignant brain tumors

(2008) Duane A. Mitchell et al.   IMMUNOLOGICAL REVIEWS

Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas

(2008) Y Komohara et al.   JOURNAL OF PATHOLOGY

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE