RelB acts as a molecular switch driving chronic inflammation in glioblastoma multiforme

RelB controls adaptive responses of astrocytes during sterile inflammation

(2019) Angela S. Gupta et al.   GLIA

Current state of immunotherapy for glioblastoma

(2018) Michael Lim et al.   Nature Reviews Clinical Oncology

Interactions between tumor-associated macrophages and tumor cells in glioblastoma: unraveling promising targeted therapies

(2018) Mony Chenda Morisse et al.   Expert Review of Neurotherapeutics

The IFN-γ/PD-L1 axis between T cells and tumor microenvironment: hints for glioma anti-PD-1/PD-L1 therapy

(2018) Jiawen Qian et al.   Journal of Neuroinflammation

Ovarian Cancer Relies on Glucose Transporter 1 to Fuel Glycolysis and Growth: Anti-Tumor Activity of BAY-876

(2018) Yibao Ma et al.   Cancers

Current Options and Future Directions in Immune Therapy for Glioblastoma

(2018) John Lynes et al.   Frontiers in Oncology

Immunotherapy and Epigenetic Pathway Modulation in Glioblastoma Multiforme

(2018) Christopher Chin et al.   Frontiers in Oncology

NIK/MAP3K14 Regulates Mitochondrial Dynamics and Trafficking to Promote Cell Invasion

(2016) Ji-Ung Jung et al.   CURRENT BIOLOGY

Human glioblastoma-associated microglia/monocytes express a distinct RNA profile compared to human control and murine samples

(2016) Frank Szulzewsky et al.   GLIA

The role of microglia and macrophages in glioma maintenance and progression

(2016) Dolores Hambardzumyan et al.   NATURE NEUROSCIENCE

Moving the needle: Optimizing classification for glioma

(2016) Roel G. W. Verhaak   Science Translational Medicine

Long-lasting pro-inflammatory suppression of microglia by LPS-preconditioning is mediated by RelB-dependent epigenetic silencing

(2015) W. Schaafsma et al.   BRAIN BEHAVIOR AND IMMUNITY

Eva1 Maintains the Stem-like Character of Glioblastoma-Initiating Cells by Activating the Noncanonical NF- B Signaling Pathway

(2015) N. Ohtsu et al.   CANCER RESEARCH

The Role of YY1 in Oncogenesis and Its Potential as a Drug Target in Cancer Therapies

(2015) Jinming Shi et al.   CURRENT CANCER DRUG TARGETS

RelB/p50 Complexes Regulate Cytokine-Induced YKL-40 Expression

(2015) Reetika Bhardwaj et al.   JOURNAL OF IMMUNOLOGY

Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) promotes glioma cell invasion through induction of NF-κB-inducing kinase (NIK) and noncanonical NF-κB signaling

(2015) Evan M Cherry et al.   Molecular Cancer

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Sequential Actions of SIRT1-RELB-SIRT3 Coordinate Nuclear-Mitochondrial Communication during Immunometabolic Adaptation to Acute Inflammation and Sepsis

(2014) Tie Fu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NF- B, an Active Player in Human Cancers

(2014) Y. Xia et al.   Cancer Immunology Research

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

The Controversial Role of Microglia in Malignant Gliomas

(2013) Jun Wei et al.   Clinical & Developmental Immunology

Glioblastoma and Other Malignant Gliomas

(2013) Antonio Omuro   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

RelB: an outlier in leukocyte biology

(2013) Patrick Millet et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Distinct roles of CSF family cytokines in macrophage infiltration and activation in glioma progression and injury response

(2013) Malgorzata Sielska et al.   JOURNAL OF PATHOLOGY

The NF-κB RelB Protein Is an Oncogenic Driver of Mesenchymal Glioma

(2013) Dong Whan Lee et al.   PLoS One

A Fourteen Gene GBM Prognostic Signature Identifies Association of Immune Response Pathway and Mesenchymal Subtype with High Risk Group

(2013) Arivazhagan Arimappamagan et al.   PLoS One

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Identification of non-canonical NF-κB signaling as a critical mediator of Smac mimetic-stimulated migration and invasion of glioblastoma cells

(2013) A Tchoghandjian et al.   Cell Death & Disease

NF-κB and the link between inflammation and cancer

(2012) Joseph A. DiDonato et al.   IMMUNOLOGICAL REVIEWS

Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways

(2012) Vincent F-S Shih et al.   NATURE IMMUNOLOGY

NAD+-dependent SIRT1 Deacetylase Participates in Epigenetic Reprogramming during Endotoxin Tolerance

(2011) Tie Fu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Factor κB Subunits RelB and cRel Negatively Regulate Toll-like Receptor 3-mediated β-Interferon Production via Induction of Transcriptional Repressor Protein YY1

(2011) Jakub Siednienko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirtuin 1 (SIRT1) Protein Degradation in Response to Persistent c-Jun N-terminal Kinase 1 (JNK1) Activation Contributes to Hepatic Steatosis in Obesity

(2011) Zhanguo Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress

(2010) Samuel Caito et al.   FASEB JOURNAL

Early termination of ISRCTN45828668, a phase 1/2 prospective, randomized study of Sulfasalazine for the treatment of progressing malignant gliomas in adults

(2009) Pierre A Robe et al.   BMC CANCER

The NF-κB Factor RelB and Histone H3 Lysine Methyltransferase G9a Directly Interact to Generate Epigenetic Silencing in Endotoxin Tolerance

(2009) Xiaoping Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The transcriptional network for mesenchymal transformation of brain tumours

(2009) Maria Stella Carro et al.   NATURE

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE