Chemical and Immunological Characteristics of Aluminum-Based, Oil-Water Emulsion, and Bacterial-Origin Adjuvants

The vaccine adjuvant MPLA activates glycolytic metabolism in mouse mDC by a JNK-dependent activation of mTOR-signaling

(2019) Frank Blanco-Pérez et al.   MOLECULAR IMMUNOLOGY

The TLR4 Agonist Monophosphoryl Lipid A Drives Broad Resistance to Infection via Dynamic Reprogramming of Macrophage Metabolism

(2018) Benjamin A. Fensterheim et al.   JOURNAL OF IMMUNOLOGY

Outer Membrane Vesicles: Current Status and Future Direction of These Novel Vaccine Adjuvants

(2018) Kuang Tan et al.   Frontiers in Microbiology

Formulation in DDA-MPLA-TDB Liposome Enhances the Immunogenicity and Protective Efficacy of a DNA Vaccine against Mycobacterium tuberculosis Infection

(2018) Maopeng Tian et al.   Frontiers in Immunology

The TLR-4 agonist adjuvant, GLA-SE, improves magnitude and quality of immune responses elicited by the ID93 tuberculosis vaccine: first-in-human trial

(2018) Rhea N. Coler et al.   npj Vaccines

Systems analysis of human vaccine adjuvants

(2018) Ali M. Harandi   SEMINARS IN IMMUNOLOGY

Novel application of trimethyl chitosan as an adjuvant in vaccine delivery

(2018) Anshu Malik et al.   International Journal of Nanomedicine

Adjuvants Enhancing Cross-Presentation by Dendritic Cells: The Key to More Effective Vaccines?

(2018) Nataschja I. Ho et al.   Frontiers in Immunology

Intraperitoneal administration of a novel chimeric immunogen (rOP) elicits IFN-γ and IL-12p70 protective immune response in BALB/c mice against virulent Brucella

(2017) Ganesh Tadepalli et al.   IMMUNOLOGY LETTERS

Rationally Designed TLR4 Ligands for Vaccine Adjuvant Discovery

(2017) Kelsey A. Gregg et al.   mBio

A structural model of flagellar filament switching across multiple bacterial species

(2017) Fengbin Wang et al.   Nature Communications

α-Tocopherol, β-carotene, lutein, squalene and secoiridoids in seven monocultivar Italian extra-virgin olive oils

(2016) Roberto Ambra et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Roles of Aluminum Hydroxide and Monophosphoryl Lipid A Adjuvants in Overcoming CD4+T Cell Deficiency To Induce Isotype-Switched IgG Antibody Responses and Protection by T-Dependent Influenza Vaccine

(2016) Eun-Ju Ko et al.   JOURNAL OF IMMUNOLOGY

Carboxyl-terminal fusion of E7 into Flagellin shifts TLR5 activation to NLRC4/NAIP5 activation and induces TLR5-independent anti-tumor immunity

(2016) Kuo-Hsing Lin et al.   Scientific Reports

On vaccine's adjuvants and autoimmunity: Current evidence and future perspectives

(2015) Paolo Pellegrino et al.   AUTOIMMUNITY REVIEWS

Freund's adjuvant, NOD2 and mycobacteria

(2015) Marcel A Behr et al.   CURRENT OPINION IN MICROBIOLOGY

ZINC 15 – Ligand Discovery for Everyone

(2015) Teague Sterling et al.   Journal of Chemical Information and Modeling

Immune Responses to HBsAg Conjugated to Protein D of Non-Typeable Haemophilus influenzae in Mice

(2015) Qiudong Su et al.   PLoS One

Decoration of Outer Membrane Vesicles with Multiple Antigens by Using an Autotransporter Approach

(2014) Maria H. Daleke-Schermerhorn et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Chemistry of Lipid A: At the Heart of Innate Immunity

(2014) Antonio Molinaro et al.   CHEMISTRY-A EUROPEAN JOURNAL

Immunomodulatory properties of the vaccine adjuvant alum

(2014) Ewa Oleszycka et al.   CURRENT OPINION IN IMMUNOLOGY

Squalene emulsion potentiates the adjuvant activity of the TLR4 agonist, GLA, via inflammatory caspases, IL-18, and IFN-γ

(2014) Anthony L. Desbien et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

NOD1 and NOD2: Signaling, Host Defense, and Inflammatory Disease

(2014) Roberta Caruso et al.   IMMUNITY

Activation of the NLRP3 inflammasome is not a feature of all particulate vaccine adjuvants

(2014) Silke Neumann et al.   IMMUNOLOGY AND CELL BIOLOGY

Inflammatory caspases are innate immune receptors for intracellular LPS

(2014) Jianjin Shi et al.   NATURE

Adjuvants for vaccines to drugs of abuse and addiction

(2014) Carl R. Alving et al.   VACCINE

Bacterial Outer Membrane Vesicles and Vaccine Applications

(2014) Reinaldo Acevedo et al.   Frontiers in Immunology

Adyuvantes inmunológicos. Determinantes en el balance eficacia-toxicidad de las vacunas contemporáneas

(2013) Alexander Batista-Duharte et al.   ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA

Structural and Biochemical Analyses ofMycobacterium tuberculosis N-Acetylmuramyl-l-alanine Amidase Rv3717 Point to a Role in Peptidoglycan Fragment Recycling

(2013) Daniil M. Prigozhin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Key roles of adjuvants in modern vaccines

(2013) Steven G Reed et al.   NATURE MEDICINE

Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

(2013) N. Kayagaki et al.   SCIENCE

Vaccine adjuvant formulations: A pharmaceutical perspective

(2013) Luis A. Brito et al.   SEMINARS IN IMMUNOLOGY

Liposomes containing monophosphoryl lipid A: A potent adjuvant system for inducing antibodies to heroin hapten analogs

(2013) Gary R. Matyas et al.   VACCINE

Vaccines against meningococcal serogroup B disease containing outer membrane vesicles (OMV): Lessons from past programs and implications for the future

(2013) Johan Holst et al.   Human Vaccines & Immunotherapeutics

Proteosome-adjuvanted intranasal influenza vaccines: advantages, progress and future considerations

(2011) David Burt et al.   Expert Review of Vaccines

Determination ofin vivotoxicity andin vitrocytotoxicity of lipopolysaccharide isolated fromSalmonellaEnteritidis and its potential use for production of polyclonal antibody

(2011) A. Nalbantsoy et al.   FOOD AND AGRICULTURAL IMMUNOLOGY

Outer Membrane Vesicles as a Candidate Vaccine against Edwardsiellosis

(2011) Seong Bin Park et al.   PLoS One

Effectiveness of a vaccination programme for an epidemic of meningococcal B in New Zealand

(2011) Richard Arnold et al.   VACCINE

Adjuvant effect of bacterial outer membrane vesicles with penta-acylated lipopolysaccharide on antigen-specific T cell priming

(2011) Dong Ho Lee et al.   VACCINE

Immunization withSalmonella entericaSerovar Typhimurium-Derived Outer Membrane Vesicles Delivering the Pneumococcal Protein PspA Confers Protection against Challenge withStreptococcus pneumoniae

(2010) Maneesha Muralinath et al.   INFECTION AND IMMUNITY

Flagellin as an Adjuvant: Cellular Mechanisms and Potential

(2010) S. B. Mizel et al.   JOURNAL OF IMMUNOLOGY

Virulence and Immunomodulatory Roles of Bacterial Outer Membrane Vesicles

(2010) T. N. Ellis et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Safety and immunogenicity of a recombinant hemagglutinin influenza–flagellin fusion vaccine (VAX125) in healthy young adults

(2010) John J. Treanor et al.   VACCINE

A Recombinant Flagellin-Poxvirus Fusion Protein Vaccine Elicits Complement-Dependent Protection Against Respiratory Challenge with Vaccinia Virus in Mice

(2010) Kristen N. Delaney et al.   VIRAL IMMUNOLOGY

Vaccination, squalene and anti-squalene antibodies: Facts or fiction?

(2009) Giuseppe Lippi et al.   European Journal of Internal Medicine

Characterization of fHbp, nhba (gna2132), nadA, porA, Sequence Type (ST), and Genomic Presence of IS1301 in Group B Meningococcal ST269 Clonal Complex Isolates from England and Wales

(2009) J. Lucidarme et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Direct Stimulation of tlr5+/+ CD11c+ Cells Is Necessary for the Adjuvant Activity of Flagellin

(2009) J. T. Bates et al.   JOURNAL OF IMMUNOLOGY

Trial of 2009 Influenza A (H1N1) Monovalent MF59-Adjuvanted Vaccine

(2009) Tristan W. Clark et al.   NEW ENGLAND JOURNAL OF MEDICINE

Superior efficacy of a recombinant flagellin:H5N1 HA globular head vaccine is determined by the placement of the globular head within flagellin

(2009) Langzhou Song et al.   VACCINE

Recombinant outer membrane vesicles to augment antigen-specific live vaccine responses

(2009) Juliane Schroeder et al.   VACCINE

Human Papillomavirus Types 16 and 18 Vaccine (Recombinant, AS04 Adjuvanted, Adsorbed) [Cervarix???]

(2008) Susan J Keam et al.   DRUGS

Engineered Bacterial Outer Membrane Vesicles with Enhanced Functionality

(2008) Jae-Young Kim et al.   JOURNAL OF MOLECULAR BIOLOGY

New horizons in adjuvants for vaccine development

(2008) Steven G. Reed et al.   TRENDS IN IMMUNOLOGY