Carboxyl-terminal fusion of E7 into Flagellin shifts TLR5 activation to NLRC4/NAIP5 activation and induces TLR5-independent anti-tumor immunity

Self-adjuvanting lipoimmunogens for therapeutic HPV vaccine development: potential clinical impact

(2014) Kuan-Yin Shen et al.   Expert Review of Vaccines

Flagellin Induces Antibody Responses through a TLR5- and Inflammasome-Independent Pathway

(2014) A. H. Lopez-Yglesias et al.   JOURNAL OF IMMUNOLOGY

Prevention of Intestinal Allergy in Mice by rflaA:Ova Is Associated with Enforced Antigen Processing and TLR5-Dependent IL-10 Secretion by mDC

(2014) Stefan Schülke et al.   PLoS One

Emerging Concepts about NAIP/NLRC4 Inflammasomes

(2014) Silvia Lucena Lage et al.   Frontiers in Immunology

Toll-Like Receptor 5-Dependent Immunogenicity and Protective Efficacy of a Recombinant Fusion Protein Vaccine Containing the Nontoxic Domains of Clostridium difficile Toxins A and B and Salmonella enterica Serovar Typhimurium Flagellin in a Mouse Model of Clostridium difficile Disease

(2013) Chandrabali Ghose et al.   INFECTION AND IMMUNITY

Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and -independent macrophage responses

(2013) S. L. Lage et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vaccination with recombinant FimH fused with flagellin enhances cellular and humoral immunity against urinary tract infection in mice

(2013) Mohammad Reza Asadi Karam et al.   VACCINE

Flagellin enhances tumor-specific CD8+ T cell immune responses through TLR5 stimulation in a therapeutic cancer vaccine model

(2013) Chung Truong Nguyen et al.   VACCINE

Formation and Structure of a NAIP5-NLRC4 Inflammasome Induced by Direct Interactions with Conserved N- and C-terminal Regions of Flagellin

(2012) Els F. Halff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recombinant Lipidated HPV E7 Induces a Th-1-Biased Immune Response and Protective Immunity against Cervical Cancer in a Mouse Model

(2012) Chiung-Yi Huang et al.   PLoS One

Structural Basis of TLR5-Flagellin Recognition and Signaling

(2012) S.-i. Yoon et al.   SCIENCE

Simultaneous Targeting of Toll- and Nod-Like Receptors Induces Effective Tumor-Specific Immune Responses

(2012) J. Garaude et al.   Science Translational Medicine

Flagellin-HA vaccines protect ferrets and mice against H5N1 highly pathogenic avian influenza virus (HPAIV) infections

(2012) Ge Liu et al.   VACCINE

Differential Requirements for NAIP5 in Activation of the NLRC4 Inflammasome

(2011) Karla L. Lightfield et al.   INFECTION AND IMMUNITY

Enhanced Antigen Processing of Flagellin Fusion Proteins Promotes the Antigen-Specific CD8+ T Cell Response Independently of TLR5 and MyD88

(2011) J. T. Bates et al.   JOURNAL OF IMMUNOLOGY

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

(2011) Yue Zhao et al.   NATURE

Immunogenicity and Efficacy of Flagellin-Fused Vaccine Candidates Targeting 2009 Pandemic H1N1 Influenza in Mice

(2011) Ge Liu et al.   PLoS One

Prediction of protein secondary structure from circular dichroism using theoretically derived spectra

(2011) Caroline Louis-Jeune et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Intranasal immunization with recombinant PspA fused with a flagellin enhances cross-protective immunity against Streptococcus pneumoniae infection in mice

(2011) Chung Truong Nguyen et al.   VACCINE

TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin

(2010) Matam Vijay-Kumar et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Induction of adaptive immunity by flagellin does not require robust activation of innate immunity

(2009) Catherine J. Sanders et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Direct Stimulation of tlr5+/+ CD11c+ Cells Is Necessary for the Adjuvant Activity of Flagellin

(2009) J. T. Bates et al.   JOURNAL OF IMMUNOLOGY

Immunization of young African green monkeys with OprF epitope 8–OprI–type A- and B-flagellin fusion proteins promotes the production of protective antibodies against nonmucoid Pseudomonasaeruginosa

(2009) Eric T. Weimer et al.   VACCINE

Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

(2008) Karla L Lightfield et al.   NATURE IMMUNOLOGY