Klotho Inhibits Unilateral Ureteral Obstruction-Induced Endothelial-to-Mesenchymal Transition via TGF-β1/Smad2/Snail1 Signaling in Mice

TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases

(2017) Evangelia Pardali et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Plasma s-Klotho is related to kidney function and predicts adverse renal outcomes in patients with advanced chronic kidney disease

(2017) Qi-feng Liu et al.   JOURNAL OF INVESTIGATIVE MEDICINE

The FGF23 and Klotho system beyond mineral metabolism

(2016) Makoto Kuro-o   Clinical and Experimental Nephrology

The origin of renal fibroblasts/myofibroblasts and the signals that trigger fibrosis

(2016) Yu Bo Yang Sun et al.   DIFFERENTIATION

Klotho mitigates cyclosporine A (CsA)-induced epithelial–mesenchymal transition (EMT) and renal fibrosis in rats

(2016) Qi-feng Liu et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic Diseases

(2016) Sonsoles Piera-Velazquez et al.   Journal of Clinical Medicine

Klotho Ameliorates Kidney Injury and Fibrosis and Normalizes Blood Pressure by Targeting the Renin-Angiotensin System

(2015) Lili Zhou et al.   AMERICAN JOURNAL OF PATHOLOGY

Renal Production, Uptake, and Handling of Circulating  Klotho

(2015) M. C. Hu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TGF-  Signaling Mediates Endothelial-to-Mesenchymal Transition (EndMT) During Vein Graft Remodeling

(2014) B. C. Cooley et al.   Science Translational Medicine

Role of the endothelial-to-mesenchymal transition in renal fibrosis of chronic kidney disease

(2013) Jianhua He et al.   Clinical and Experimental Nephrology

Serum levels of soluble secreted α-Klotho are decreased in the early stages of chronic kidney disease, making it a probable novel biomarker for early diagnosis

(2012) Yoshiko Shimamura et al.   Clinical and Experimental Nephrology

Klotho Inhibits Transforming Growth Factor-β1 (TGF-β1) Signaling and Suppresses Renal Fibrosis and Cancer Metastasis in Mice

(2011) Shigehiro Doi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blockade of Endothelial-Mesenchymal Transition by a Smad3 Inhibitor Delays the Early Development of Streptozotocin-Induced Diabetic Nephropathy

(2010) J. Li et al.   DIABETES

Snail is required for TGF -induced endothelial-mesenchymal transition of embryonic stem cell-derived endothelial cells

(2008) T. Kokudo et al.   JOURNAL OF CELL SCIENCE