The Configuration of the Perivascular System Transporting Macromolecules in the CNS

Structural characterization of the α-N-acetylglucosaminidase, a key enzyme in the pathogenesis of Sanfilippo syndrome B

(2019) Gabriel Birrane et al.   JOURNAL OF STRUCTURAL BIOLOGY

Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways

(2018) Nazira J. Albargothy et al.   ACTA NEUROPATHOLOGICA

Why Do So Many Drugs for Alzheimer's Disease Fail in Development? Time for New Methods and New Practices?

(2017) Robert E. Becker et al.   JOURNAL OF ALZHEIMERS DISEASE

Spatial model of convective solute transport in brain extracellular space does not support a “glymphatic” mechanism

(2016) Byung-Ju Jin et al.   JOURNAL OF GENERAL PHYSIOLOGY

A diffusion tensor MRI atlas of the postmortem rhesus macaque brain

(2015) Evan Calabrese et al.   NEUROIMAGE

Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies

(2014) Samir Mitragotri et al.   NATURE REVIEWS DRUG DISCOVERY

Physiology of the Intrathecal Bolus: The Leptomeningeal Route for Macromolecule and Particle Delivery to CNS

(2013) Mikhail I. Papisov et al.   MOLECULAR PHARMACEUTICS

CNS Penetration of Intrathecal-Lumbar Idursulfase in the Monkey, Dog and Mouse: Implications for Neurological Outcomes of Lysosomal Storage Disorder

(2012) Pericles Calias et al.   PLoS One

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Investigation of intrathecal transport of NPT002, a prospective therapeutic based on phage M13, in nonhuman primates

(2012) Mikhail I. Papisov et al.   Drug Delivery and Translational Research

Delivery of proteins to CNS as seen and measured by positron emission tomography

(2012) Mikhail I. Papisov et al.   Drug Delivery and Translational Research

Guided delivery of adeno-associated viral vectors into the primate brain

(2011) Ernesto A. Salegio et al.   ADVANCED DRUG DELIVERY REVIEWS

Modern methods for delivery of drugs across the blood–brain barrier

(2011) Yan Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

The Effect of Pulsatile Flow on Intrathecal Drug Delivery in the Spinal Canal

(2011) H. D. M. Hettiarachchi et al.   ANNALS OF BIOMEDICAL ENGINEERING

Biopharmaceutical drug targeting to the brain

(2010) William M. Pardridge   JOURNAL OF DRUG TARGETING

Delivery of peptides to the brain: Emphasis on therapeutic development

(2008) William A. Banks   BIOPOLYMERS

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology

(2008) R. O. Carare et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY