Inhibition of glycolysis disrupts cellular antioxidant defense and sensitizes HepG2 cells to doxorubicin treatment

Molecular link between glucose and glutamine consumption in cancer cells mediated by CtBP and SIRT4

(2018) Li Wang et al.   Oncogenesis

Inhibition of malic enzyme 1 disrupts cellular metabolism and leads to vulnerability in cancer cells in glucose-restricted conditions

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Complex I inhibition augments dichloroacetate cytotoxicity through enhancing oxidative stress in VM-M3 glioblastoma cells

(2017) Nathan P. Ward et al.   PLoS One

Review on the binding of anticancer drug doxorubicin with DNA and tRNA: Structural models and antitumor activity

(2016) D. Agudelo et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Glycolysis Inhibitors for Anticancer Therapy: A Review of Recent Patents

(2016) Huaming Sheng et al.   Recent Patents on Anti-Cancer Drug Discovery

Inhibition of cancer antioxidant defense by natural compounds

(2016) Alicja Sznarkowska et al.   Oncotarget

Anthracyclines induce double-strand DNA breaks at active gene promoters

(2015) Fan Yang et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Glycolysis inhibition and its effect in doxorubicin resistance in neuroblastoma

(2014) Jonathan F. Bean et al.   JOURNAL OF PEDIATRIC SURGERY

PCK2 activation mediates an adaptive response to glucose depletion in lung cancer

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Oxidative stress on cardiotoxicity after treatment with single and multiple doses of doxorubicin

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Tumor glycolysis as a target for cancer therapy: progress and prospects

(2013) Shanmugasundaram Ganapathy-Kanniappan et al.   Molecular Cancer

Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia

(2013) J. Fan et al.   Molecular Systems Biology

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells

(2012) Anne Le et al.   Cell Metabolism

3-bromopyruvate: Targets and outcomes

(2012) Maria C. Shoshan   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

The Warburg effect: Insights from the past decade

(2012) Mohita Upadhyay et al.   PHARMACOLOGY & THERAPEUTICS

Glycolysis Inhibition Inactivates ABC Transporters to Restore Drug Sensitivity in Malignant Cells

(2011) Ayako Nakano et al.   PLoS One

Dichloroacetate Induces Apoptosis of Epithelial Ovarian Cancer Cells Through a Mechanism Involving Modulation of Oxidative Stress

(2011) Ghassan M. Saed et al.   Reproductive Sciences

2-deoxy-D-glucose induces oxidative stress and cell killing in human neuroblastoma cells

(2010) Damon Shutt et al.   CANCER BIOLOGY & THERAPY

Autophagy in cancer associated fibroblasts promotes tumor cell survival

(2010) Ubaldo E. Martinez-Outschoorn et al.   CELL CYCLE

The engine driving the ship: metabolic steering of cell proliferation and death

(2010) Marisa R. Buchakjian et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

Cellular life span and the Warburg effect

(2008) Hiroshi Kondoh   EXPERIMENTAL CELL RESEARCH

Role of reactive oxygen species-mediated mitochondrial dysregulation in 3-bromopyruvate induced cell death in hepatoma cells

(2008) Ji Su Kim et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

2-Deoxy-d-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer

(2007) Mitchell C. Coleman et al.   FREE RADICAL BIOLOGY AND MEDICINE