Alzheimer’s disease polygenic risk score as a predictor of conversion from mild-cognitive impairment

Polygenic Risk Score for Alzheimer’s Disease: Implications for Memory Performance and Hippocampal Volumes in Early Life

(2018) Luiza K. Axelrud et al.   AMERICAN JOURNAL OF PSYCHIATRY

Genotyping of the Alzheimer’s Disease Genome-Wide Association Study Index Single Nucleotide Polymorphisms in the Brains for Dementia Research Cohort

(2018) Keeley J. Brookes et al.   JOURNAL OF ALZHEIMERS DISEASE

Use of an Alzheimer’s disease polygenic risk score to identify mild cognitive impairment in adults in their 50s

(2018) Mark W. Logue et al.   MOLECULAR PSYCHIATRY

The personal and clinical utility of polygenic risk scores

(2018) Ali Torkamani et al.   NATURE REVIEWS GENETICS

Polygenic risk score in postmortem diagnosed sporadic early-onset Alzheimer's disease

(2018) Sultan Chaudhury et al.   NEUROBIOLOGY OF AGING

Effects of Alzheimer's Disease-Associated Risk Loci on Cerebrospinal Fluid Biomarkers and Disease Progression: A Polygenic Risk Score Approach

(2018) Henna Martiskainen et al.   JOURNAL OF ALZHEIMERS DISEASE

Brains for Dementia Research: Evolution in a Longitudinal Brain Donation Cohort to Maximize Current and Future Value

(2018) Paul T. Francis et al.   JOURNAL OF ALZHEIMERS DISEASE

The Correlation between Inflammatory Biomarkers and Polygenic Risk Score in Alzheimer’s Disease

(2017) Angharad R. Morgan et al.   JOURNAL OF ALZHEIMERS DISEASE

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

(2017) Rebecca Sims et al.   NATURE GENETICS

NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases

(2017) Cornelis Blauwendraat et al.   NEUROBIOLOGY OF AGING

Polygenic score prediction captures nearly all common genetic risk for Alzheimer's disease

(2017) Valentina Escott-Price et al.   NEUROBIOLOGY OF AGING

Polygenic risk scores in familial Alzheimer disease

(2017) Giuseppe Tosto et al.   NEUROLOGY

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

(2017) Rahul S. Desikan et al.   PLOS MEDICINE

Association between apolipoprotein E gene polymorphism and mild cognitive impairment: a meta-analysis

(2017) Yunxia Jiang et al.   Clinical Interventions in Aging

Using an Alzheimer Disease Polygenic Risk Score to Predict Memory Decline in Black and White Americans Over 14 Years of Follow-up

(2016) Jessica R. Marden et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Genome research in pre-dementia stages of Alzheimer's disease

(2016) Sonia Moreno-Grau et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer’s Disease

(2016) Vincent Chouraki et al.   JOURNAL OF ALZHEIMERS DISEASE

The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume

(2016) Michelle K. Lupton et al.   NEUROBIOLOGY OF AGING

Polygenic risk of Alzheimer disease is associated with early- and late-life processes

(2016) Elizabeth C. Mormino et al.   NEUROLOGY

Genetic risk of neurodegenerative diseases is associated with mild cognitive impairment and conversion to dementia

(2015) Hieab H.H. Adams et al.   Alzheimers & Dementia

A 22-single nucleotide polymorphism Alzheimer's disease risk score correlates with family history, onset age, and cerebrospinal fluid Aβ 42

(2015) Kristel Sleegers et al.   Alzheimers & Dementia

PRROC: computing and visualizing precision-recall and receiver operating characteristic curves in R

(2015) Jan Grau et al.   BIOINFORMATICS

Decision tree analysis of genetic risk for clinically heterogeneous Alzheimer’s disease

(2015) Jennifer S Yokoyama et al.   BMC Neurology

Common polygenic variation enhances risk prediction for Alzheimer’s disease

(2015) Valentina Escott-Price et al.   BRAIN

Late-onset Alzheimer’s risk variants in memory decline, incident mild cognitive impairment, and Alzheimer’s disease

(2015) Minerva M. Carrasquillo et al.   NEUROBIOLOGY OF AGING

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

The Precision-Recall Plot Is More Informative than the ROC Plot When Evaluating Binary Classifiers on Imbalanced Datasets

(2015) Takaya Saito et al.   PLoS One

PRSice: Polygenic Risk Score software

(2014) Jack Euesden et al.   BIOINFORMATICS

Systemic inflammatory responses to stress and its impact on cognition in people with mild cognitive impairment

(2013) Rebecca Sussams et al.   Alzheimers & Dementia

Genome-wide Association Studies in Alzheimer’s Disease: A Review

(2013) Giuseppe Tosto et al.   Current Neurology and Neuroscience Reports

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Alzheimer's Disease Genes and Cognition in the Nondemented General Population

(2012) Benjamin F.J. Verhaaren et al.   BIOLOGICAL PSYCHIATRY

Genetic risk score predicting accelerated progression from mild cognitive impairment to Alzheimer’s disease

(2012) E. Rodríguez-Rodríguez et al.   JOURNAL OF NEURAL TRANSMISSION

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Association between a Polygenic Alzheimer Score and Cortical Thickness in Clinically Normal Subjects

(2011) Mert R. Sabuncu et al.   CEREBRAL CORTEX

Rate of progression of mild cognitive impairment to dementia - meta-analysis of 41 robust inception cohort studies

(2009) A. J. Mitchell et al.   ACTA PSYCHIATRICA SCANDINAVICA

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS