Berberine activates Nrf2 nuclear translocation and inhibits apoptosis induced by high glucose in renal tubular epithelial cells through a phosphatidylinositol 3-kinase/Akt-dependent mechanism

Augmenter of liver regeneration plays a protective role against hydrogen peroxide-induced oxidative stress in renal proximal tubule cells

(2015) Ning Xia et al.   APOPTOSIS

Phosphocreatine protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by modulating the PI3K/Akt/eNOS pathway

(2015) Anil Ahsan et al.   APOPTOSIS

Morin mitigates acetaminophen-induced liver injury by potentiating Nrf2 regulated survival mechanism through molecular intervention in PHLPP2-Akt-Gsk3β axis

(2015) Fatima Rizvi et al.   APOPTOSIS

Relationship of adiponectin to markers of oxidative stress in type 2 diabetic patients: influence of incipient diabetes-associated kidney disease

(2015) Cosmina Ioana Bondor et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Sulforaphane attenuation of experimental diabetic nephropathy involves GSK-3 beta/Fyn/Nrf2 signaling pathway

(2015) Guoguo Shang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Peroxiredoxin 1 inhibits the oxidative stress induced apoptosis in renal tubulointerstitial fibrosis

(2015) Wenjuan Mei et al.   NEPHROLOGY

Berberine reduces ischemia/reperfusion-induced myocardial apoptosis via activating AMPK and PI3K–Akt signaling in diabetic rats

(2014) Keke Chen et al.   APOPTOSIS

Inhibition of Src Kinase Blocks High Glucose-Induced EGFR Transactivation and Collagen Synthesis in Mesangial Cells and Prevents Diabetic Nephropathy in Mice

(2013) K. Taniguchi et al.   DIABETES

Berberine protects human renal proximal tubular cells from hypoxia/reoxygenation injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways

(2013) Wenli Yu et al.   Journal of Translational Medicine

Role of impaired Nrf2 activation in the pathogenesis of oxidative stress and inflammation in chronic tubulo-interstitial nephropathy

(2013) Mohammad A. Aminzadeh et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Berberine, a natural antidiabetes drug, attenuates glucose neurotoxicity and promotes Nrf2-related neurite outgrowth

(2013) Ya-Yun Hsu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Berberine activates Nrf2 nuclear translocation and protects against oxidative damage via a phosphatidylinositol 3-kinase/Akt-dependent mechanism in NSC34 motor neuron-like cells

(2012) Ya-Yun Hsu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Role of Contrast Media on Oxidative Stress, Ca2+ Signaling and Apoptosis in Kidney

(2012) Mustafa Nazıroğlu et al.   JOURNAL OF MEMBRANE BIOLOGY

Molecular role of catalase on oxidative stress-induced Ca2+signaling and TRP cation channel activation in nervous system

(2012) Mustafa Nazıroğlu   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Renoprotective effects of berberine and its possible molecular mechanisms in combination of high-fat diet and low-dose streptozotocin-induced diabetic rats

(2012) Feng Ling Wang et al.   MOLECULAR BIOLOGY REPORTS

Role of Oxidative Stress and Ca2+ Signaling on Molecular Pathways of Neuropathic Pain in Diabetes: Focus on TRP Channels

(2012) Mustafa Nazıroğlu et al.   NEUROCHEMICAL RESEARCH

Ameliorative effect of berberine on renal damage in rats with diabetes induced by high-fat diet and streptozotocin

(2012) Duo Wu et al.   PHYTOMEDICINE

Lipid-lowering effect of berberine in human subjects and rats

(2012) Yueshan Hu et al.   PHYTOMEDICINE

Bcl-2-Modifying Factor Induces Renal Proximal Tubular Cell Apoptosis in Diabetic Mice

(2011) G. J. Lau et al.   DIABETES

The Tuberin/mTOR Pathway Promotes Apoptosis of Tubular Epithelial Cells in Diabetes

(2011) C. Velagapudi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cell apoptosis induced by zinc deficiency in osteoblastic MC3T3-E1 cells via a mitochondrial-mediated pathway

(2011) Baolei Guo et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Role of the Nrf2-heme oxygenase-1 pathway in silver nanoparticle-mediated cytotoxicity

(2011) Su Jin Kang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Nrf2-ARE Pathway

(2010) Jeffrey A. Johnson et al.   Annals of the New York Academy of Sciences

The Protective Role of Nrf2 in Streptozotocin-Induced Diabetic Nephropathy

(2010) T. Jiang et al.   DIABETES

Effects of berberine on matrix accumulation and NF-kappa B signal pathway in alloxan-induced diabetic mice with renal injury

(2010) Weihua Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

BASP1 Promotes Apoptosis in Diabetic Nephropathy

(2010) M. D. Sanchez-Nino et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase

(2009) Yiqun Wang et al.   CARDIOVASCULAR RESEARCH

Outer membrane VDAC1 controls permeability transition of the inner mitochondrial membrane in cellulo during stress-induced apoptosis

(2009) Flora Tomasello et al.   CELL RESEARCH

Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression

(2009) Hao Zhang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders

(2009) Jiyoung Kim et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Pharmacological and Clinical Aspects of Heme Oxygenase

(2008) N. G. Abraham et al.   PHARMACOLOGICAL REVIEWS