Morin mitigates acetaminophen-induced liver injury by potentiating Nrf2 regulated survival mechanism through molecular intervention in PHLPP2-Akt-Gsk3β axis

Turning Off AKT: PHLPP as a Drug Target

(2014) Alexandra C. Newton et al.   Annual Review of Pharmacology and Toxicology

Aluminium Induced Endoplasmic Reticulum Stress Mediated Cell Death in SH-SY5Y Neuroblastoma Cell Line Is Independent of p53

(2014) Syed Husain Mustafa Rizvi et al.   PLoS One

Essential role of PH domain and leucine-rich repeat protein phosphatase 2 in Nrf2 suppression via modulation of Akt/GSK3β/Fyn kinase axis during oxidative hepatocellular toxicity

(2014) F Rizvi et al.   Cell Death & Disease

Signal Transduction and Molecular Targets of Selected Flavonoids

(2013) Ann M. Bode et al.   ANTIOXIDANTS & REDOX SIGNALING

Source and characterization of hepatic macrophages in acetaminophen-induced acute liver failure in humans

(2012) Charalambos Gustav Antoniades et al.   HEPATOLOGY

High-mobility group box 1 (HMGB1)-toll-like receptor (TLR)4-interleukin (IL)-23-IL-17A axis in drug-induced damage-associated lethal hepatitis: Interaction of γδ T cells with macrophages

(2012) Xuefu Wang et al.   HEPATOLOGY

Diacylglycerol Kinase δ Modulates Akt Phosphorylation through Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatase 2 (PHLPP2)

(2012) Tracy M. Crotty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protective Role of Morin, a Flavonoid, against High Glucose Induced Oxidative Stress Mediated Apoptosis in Primary Rat Hepatocytes

(2012) Radhika Kapoor et al.   PLoS One

Tramadol/paracetamol fixed-dose combination in the treatment of moderate to severe pain

(2012) Joseph Pergolizzi et al.   Journal of Pain Research

Staggered overdose pattern and delay to hospital presentation are associated with adverse outcomes following paracetamol-induced hepatotoxicity

(2011) Darren G. N. Craig et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress-Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo

(2011) Y. Tan et al.   DIABETES

Acetaminophen overdose-induced liver injury in mice is mediated by peroxynitrite independently of the cyclophilin D-regulated permeability transition

(2011) Amanda LoGuidice et al.   HEPATOLOGY

Role of the Nalp3 inflammasome in acetaminophen-induced sterile inflammation and liver injury

(2011) C. David Williams et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Flavonoids as Protein Kinase Inhibitors for Cancer Chemoprevention: Direct Binding and Molecular Modeling

(2010) De-Xing Hou et al.   ANTIOXIDANTS & REDOX SIGNALING

Mst1 Is an Interacting Protein that Mediates PHLPPs' Induced Apoptosis

(2010) Meng Qiao et al.   MOLECULAR CELL

Morin inhibits Fyn kinase in mast cells and IgE-mediated type I hypersensitivity response in vivo

(2009) Jie Wan Kim et al.   BIOCHEMICAL PHARMACOLOGY

Adverse reactions associated with acetylcysteine

(2009) E.A. Sandilands et al.   CLINICAL TOXICOLOGY

Dysregulation of glutathione synthesis during cholestasis in mice: Molecular mechanisms and therapeutic implications

(2009) Heping Yang et al.   HEPATOLOGY

Nrf2 as a Master Redox Switch in Turning on the Cellular Signaling Involved in the Induction of Cytoprotective Genes by Some Chemopreventive Phytochemicals

(2008) Young-Joon Surh et al.   PLANTA MEDICA