Rodent Models of Developmental Ischemic Stroke for Translational Research: Strengths and Weaknesses

Adiponectin attenuates neuronal apoptosis induced by hypoxia-ischemia via the activation of AdipoR1/APPL1/LKB1/AMPK pathway in neonatal rats

(2018) Ningbo Xu et al.   NEUROPHARMACOLOGY

Combination of Constraint-Induced Movement Therapy with Electroacupuncture Improves Functional Recovery following Neonatal Hypoxic-Ischemic Brain Injury in Rats

(2018) Hyunha Kim et al.   Biomed Research International

AMPK activation: Role in the signaling pathways of neuroinflammation and neurodegeneration

(2017) Christina Alves Peixoto et al.   EXPERIMENTAL NEUROLOGY

Modification to the Rice-Vannucci perinatal hypoxic-ischaemic encephalopathy model in the P7 rat improves the reliability of cerebral infarct development after 48 hours

(2017) Adam B. Edwards et al.   JOURNAL OF NEUROSCIENCE METHODS

Skilled Movements Require Non-apoptotic Bax/Bak Pathway-Mediated Corticospinal Circuit Reorganization

(2017) Zirong Gu et al.   NEURON

Pediatric brain repair from endogenous neural stem cells of the subventricular zone

(2017) Yusuke Niimi et al.   PEDIATRIC RESEARCH

Focal Stroke in the Developing Rat Motor Cortex Induces Age- and Experience-Dependent Maladaptive Plasticity of Corticospinal System

(2017) Mariangela Gennaro et al.   Frontiers in Neural Circuits

Identification of Intrinsic Axon Growth Modulators for Intact CNS Neurons after Injury

(2017) Kathren L. Fink et al.   Cell Reports

Early, Accurate Diagnosis and Early Intervention in Cerebral Palsy

(2017) Iona Novak et al.   JAMA Pediatrics

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats

(2017) Amara Larpthaveesarp et al.   Jove-Journal of Visualized Experiments

Role of Perinatal Inflammation in Neonatal Arterial Ischemic Stroke

(2017) Antoine Giraud et al.   Frontiers in Neurology

Compensatory Actions of Ldb Adaptor Proteins During Corticospinal Motor Neuron Differentiation

(2016) Dino P. Leone et al.   CEREBRAL CORTEX

Which Aspects of Stroke Do Animal Models Capture? A Multitracer Micro-PET Study of Focal Ischemia with Endothelin-1

(2016) Ralf Schirrmacher et al.   CEREBROVASCULAR DISEASES

The corticospinal tract: Evolution, development, and human disorders

(2016) Quentin Welniarz et al.   Developmental Neurobiology

Major remodeling of brain microvessels during neonatal period in the mouse: A proteomic and transcriptomic study

(2016) Baptiste Porte et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Inhibition of Signal Transducer and Activator of Transcription 3 (STAT3) reduces neonatal hypoxic-ischaemic brain damage

(2016) Mariya Hristova et al.   JOURNAL OF NEUROCHEMISTRY

Microglial Cells Prevent Hemorrhage in Neonatal Focal Arterial Stroke

(2016) D. Fernandez-Lopez et al.   JOURNAL OF NEUROSCIENCE

GSK3β inhibition protects the immature brain from hypoxic-ischaemic insult via reduced STAT3 signalling

(2016) Barbara D'Angelo et al.   NEUROPHARMACOLOGY

Rodent Hypoxia–Ischemia Models for Cerebral Palsy Research: A Systematic Review

(2016) Prakasham Rumajogee et al.   Frontiers in Neurology

Motor Experience Reprograms Development of a Genetically-Altered Bilateral Corticospinal Motor Circuit

(2016) Najet Serradj et al.   PLoS One

Circulating biologic markers of endothelial dysfunction in cerebral small vessel disease: A review

(2015) Anna Poggesi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Paediatric stroke: pressing issues and promising directions

(2015) Adam Kirton et al.   LANCET NEUROLOGY

The role of inflammation in perinatal brain injury

(2015) Henrik Hagberg et al.   Nature Reviews Neurology

Sip1 Downstream Effector ninein Controls Neocortical Axonal Growth, Ipsilateral Branching, and Microtubule Growth and Stability

(2015) Swathi Srivatsa et al.   NEURON

Pathophysiology and Neuroprotection of Global and Focal Perinatal Brain Injury: Lessons From Animal Models

(2015) Luigi Titomanlio et al.   PEDIATRIC NEUROLOGY

Animal models of ischemic stroke and their application in clinical research

(2015) Christoph Kleinschnitz et al.   Drug Design Development and Therapy

Neuroinflammation and Neuroimmune Dysregulation after Acute Hypoxic-Ischemic Injury of Developing Brain

(2015) Utpal S. Bhalala et al.   Frontiers in Pediatrics

Satb2 Regulates the Differentiation of Both Callosal and Subcerebral Projection Neurons in the Developing Cerebral Cortex

(2014) Dino P. Leone et al.   CEREBRAL CORTEX

Harnessing the power of neuroplasticity for intervention

(2014) Bryan Kolb et al.   Frontiers in Human Neuroscience

Mechanisms of Perinatal Arterial Ischemic Stroke

(2014) David Fernández-López et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Differential roles of microglia and monocytes in the inflamed central nervous system

(2014) Ryo Yamasaki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

EphA4-Mediated Ipsilateral Corticospinal Tract Misprojections Are Necessary for Bilateral Voluntary Movements But Not Bilateral Stereotypic Locomotion

(2014) N. Serradj et al.   JOURNAL OF NEUROSCIENCE

Barrier mechanisms in neonatal stroke

(2014) Ingrid Kratzer et al.   Frontiers in Neuroscience

What are the Best Animal Models for Testing Early Intervention in Cerebral Palsy?

(2014) Gavin John Clowry et al.   Frontiers in Neurology

Increased susceptibility to pentetrazol-induced seizures in developing rats after cortical photothrombotic ischemic stroke at P7

(2013) T. Brima et al.   BRAIN RESEARCH

Perilesional Treatment with Chondroitinase ABC and Motor Training Promote Functional Recovery After Stroke in Rats

(2013) L. Gherardini et al.   CEREBRAL CORTEX

Predicting developmental plasticity after perinatal stroke

(2013) Adam Kirton   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Temporal Expression of Cytokines and Signal Transducer and Activator of Transcription Factor 3 Activation after Neonatal Hypoxia/Ischemia in Mice

(2013) K. Shrivastava et al.   DEVELOPMENTAL NEUROSCIENCE

A novel reproducible model of neonatal stroke in mice: Comparison with a hypoxia–ischemia model

(2013) Masahiro Tsuji et al.   EXPERIMENTAL NEUROLOGY

EphrinB3/EphA4-Mediated Guidance of Ascending and Descending Spinal Tracts

(2013) Sónia Paixão et al.   NEURON

Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species

(2013) Bridgette D. Semple et al.   PROGRESS IN NEUROBIOLOGY

Experimental Pediatric Arterial Ischemic Stroke Model Reveals Sex-specific Estrogen Signaling

(2013) Paco S. Herson et al.   STROKE

Life After Perinatal Stroke

(2013) Adam Kirton et al.   STROKE

Displacement of Sensory Maps and Disorganization of Motor Cortex After Targeted Stroke in Mice

(2013) T. C. Harrison et al.   STROKE

Characterisation of Endothelin-1-Induced Intrastriatal Lesions Within the Juvenile and Adult Rat Brain Using MRI and 31P MRS

(2013) Raman Saggu   Translational Stroke Research

Association between Endothelial Dysfunction and Acute Brain Dysfunction during Critical Illness

(2012) Christopher G. Hughes et al.   ANESTHESIOLOGY

Delayed treatment with chondroitinase ABC promotes sensorimotor recovery and plasticity after stroke in aged rats

(2012) Sara Soleman et al.   BRAIN

Chondroitinase ABC promotes compensatory sprouting of the intact corticospinal tract and recovery of forelimb function following unilateral pyramidotomy in adult mice

(2012) Michelle L. Starkey et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Expression of the Nrf2-system at the blood-CSF barrier is modulated by neonatal inflammation and hypoxia-ischemia

(2012) Barbara D’Angelo et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Blood-Brain Barrier Permeability Is Increased After Acute Adult Stroke But Not Neonatal Stroke in the Rat

(2012) D. Fernandez-Lopez et al.   JOURNAL OF NEUROSCIENCE

Enhanced NMDA receptor tyrosine phosphorylation and increased brain injury following neonatal hypoxia–ischemia in mice with neuronal Fyn overexpression

(2012) Renatta Knox et al.   NEUROBIOLOGY OF DISEASE

Motor Circuits in Action: Specification, Connectivity, and Function

(2012) Silvia Arber   NEURON

Microglia in development: linking brain wiring to brain environment

(2012) Rosa C. Paolicelli et al.   Neuron Glia Biology

Kruppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract

(2012) M. G. Blackmore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Yin and Yen of GABA in Brain Development and Operation in Health and Disease

(2012) Yehezkel Ben-Ari   Frontiers in Cellular Neuroscience

Motoring ahead with rodents

(2011) Bence P Ölveczky   CURRENT OPINION IN NEUROBIOLOGY

Differential contributions of rostral and caudal frontal forelimb areas to compensatory process after neonatal hemidecortication in rats

(2011) Tatsuya Umeda et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Microglial Cells Contribute to Endogenous Brain Defenses after Acute Neonatal Focal Stroke

(2011) J. V. Faustino et al.   JOURNAL OF NEUROSCIENCE

Endothelin-1 is upregulated after traumatic brain injury: a cross-species, cross-model analysis

(2011) William M Armstead et al.   NEUROLOGICAL RESEARCH

Symptomatic Neonatal Arterial Ischemic Stroke: The International Pediatric Stroke Study

(2011) A. Kirton et al.   PEDIATRICS

Stroke in children under 16 years of age. Clinical and etiological difference with adults

(2010) M. Giroud et al.   ACTA NEUROLOGICA SCANDINAVICA

Functional Deficit and Recovery of Developing Sensorimotor Networks following Neonatal Hypoxic-Ischemic Injury in the Rat

(2010) C. Quairiaux et al.   CEREBRAL CORTEX

The Organization of the Forelimb Representation of the C57BL/6 Mouse Motor Cortex as Defined by Intracortical Microstimulation and Cytoarchitecture

(2010) Kelly A. Tennant et al.   CEREBRAL CORTEX

Cortical excitability and interhemispheric inhibition after subcortical pediatric stroke: Plastic organization and effects of rTMS☆

(2010) Adam Kirton et al.   CLINICAL NEUROPHYSIOLOGY

PTEN deletion enhances the regenerative ability of adult corticospinal neurons

(2010) Kai Liu et al.   NATURE NEUROSCIENCE

Attenuation of Reactive Gliosis Does Not Affect Infarct Volume in Neonatal Hypoxic-Ischemic Brain Injury in Mice

(2010) Katarina Järlestedt et al.   PLoS One

Does Inflammation after Stroke Affect the Developing Brain Differently than Adult Brain?

(2009) Zinaida S. Vexler et al.   DEVELOPMENTAL NEUROSCIENCE

Fgfr1 Is Required for Cortical Regeneration and Repair after Perinatal Hypoxia

(2009) D. M. Fagel et al.   JOURNAL OF NEUROSCIENCE

Animal Models of Perinatal Hypoxic-Ischemic Brain Damage

(2009) Jerome Y. Yager et al.   PEDIATRIC NEUROLOGY

Sex, Sex Steroids, and Brain Injury

(2009) Paco Herson et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Primary cortical folding in the human newborn: an early marker of later functional development

(2008) J. Dubois et al.   BRAIN

Endothelin-1 Regulates Astrocyte Proliferation and Reactive Gliosis via a JNK/c-Jun Signaling Pathway

(2008) A. Gadea et al.   JOURNAL OF NEUROSCIENCE

Early postnatal development of rat brain: In vivo diffusion tensor imaging

(2008) K.H. Bockhorst et al.   JOURNAL OF NEUROSCIENCE RESEARCH

SOX5 Controls the Sequential Generation of Distinct Corticofugal Neuron Subtypes

(2008) Tina Lai et al.   NEURON

Molecular mechanisms of axon guidance in the developing corticospinal tract

(2008) A.J. Canty et al.   PROGRESS IN NEUROBIOLOGY

Rapid Morphologic Plasticity of Peri-Infarct Dendritic Spines After Focal Ischemic Stroke

(2008) Craig E. Brown et al.   STROKE

Development of a Rat Model of Photothrombotic Ischemia and Infarction Within the Caudoputamen

(2008) Toshihiko Kuroiwa et al.   STROKE