Melatonin Affects Mitochondrial Fission/Fusion Dynamics in the Diabetic Retina

New insights into the role of mitochondrial calcium homeostasis in cell migration

(2018) Vincent Paupe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Therapeutic targets for altering mitochondrial dysfunction associated with diabetic retinopathy

(2018) Renu A. Kowluru et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Restoring mitochondrial calcium uniporter expression in diabetic mouse heart improves mitochondrial calcium handling and cardiac function

(2018) Jorge Suarez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Circadian Regulation of Mitochondrial Dynamics in Retinal Photoreceptors

(2018) Janet Ya-An Chang et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Mitochondria Maintain Distinct Ca 2+ Pools in Cone Photoreceptors

(2017) Michelle M. Giarmarco et al.   JOURNAL OF NEUROSCIENCE

Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release

(2017) Yalikun Suofu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Melatonin on Glucose Homeostasis, Antioxidant Ability, and Adipokine Secretion in ICR Mice with NA/STZ-Induced Hyperglycemia

(2017) Chung-Cheng Lo et al.   Nutrients

Expression of the mitochondrial calcium uniporter in cardiac myocytes improves impaired mitochondrial calcium handling and metabolism in simulated hyperglycemia

(2016) Julieta Diaz-Juarez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Functional Deficits Precede Structural Lesions in Mice With High-Fat Diet–Induced Diabetic Retinopathy

(2016) Rithwick Rajagopal et al.   DIABETES

Melatonin prevents adverse myocardial infarction remodeling via Notch1/Mfn2 pathway

(2016) Haifeng Pei et al.   FREE RADICAL BIOLOGY AND MEDICINE

Melatonin antagonizes cadmium-induced neurotoxicity by activating the transcription factor EB-dependent autophagy-lysosome machinery in mouse neuroblastoma cells

(2016) Min Li et al.   JOURNAL OF PINEAL RESEARCH

Melatonin prevents the dynamin-related protein 1-dependent mitochondrial fission and oxidative insult in the cortical neurons after 1-methyl-4-phenylpyridinium treatment

(2016) Jih-Ing Chuang et al.   JOURNAL OF PINEAL RESEARCH

Mitofusins, from Mitochondria to Metabolism

(2016) Emilie Schrepfer et al.   MOLECULAR CELL

Melatonin prevents cytosolic calcium overload, mitochondrial damage and cell death due to toxically high doses of dexamethasone-induced oxidative stress in human neuroblastoma SH-SY5Y cells

(2016) Wilasinee Suwanjang et al.   NEUROCHEMISTRY INTERNATIONAL

Protective Effects of Melatonin on Retinal Inflammation and Oxidative Stress in Experimental Diabetic Retinopathy

(2016) Tingting Jiang et al.   Oxidative Medicine and Cellular Longevity

Increased melatonin levels in aqueous humor of patients with proliferative retinopathy in type 2 diabetes mellitus

(2016)   International Journal of Ophthalmology

Deletion of miR-150 Exacerbates Retinal Vascular Overgrowth in High-Fat-Diet Induced Diabetic Mice

(2016) Liheng Shi et al.   PLoS One

Melatonin, quercetin and resveratrol attenuates oxidative hepatocellular injury in streptozotocin-induced diabetic rats

(2015) H Elbe et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Changes in mitochondrial morphology induced by calcium or rotenone in primary astrocytes occur predominantly through ros-mediated remodeling

(2015) Samineh Deheshi et al.   JOURNAL OF NEUROCHEMISTRY

Melatonin reduces hepatic mitochondrial dysfunction in diabetic obese rats

(2015) Ahmad Agil et al.   JOURNAL OF PINEAL RESEARCH

Melatonin prevents retinal oxidative stress and vascular changes in diabetic rats

(2014) G Özdemir et al.   EYE

Melatonin attenuates inflammatory response-induced brain edema in early brain injury following a subarachnoid hemorrhage: a possible role for the regulation of pro-inflammatory cytokines

(2014) Jingyin Chen et al.   JOURNAL OF PINEAL RESEARCH

The effectiveness of melatonin for promoting healthy sleep: a rapid evidence assessment of the literature

(2014) Rebecca B Costello et al.   Nutrition Journal

Chicken Embryos as a Potential New Model for Early Onset Type I Diabetes

(2014) Liheng Shi et al.   Journal of Diabetes Research

Mitochondrial Dynamics Controlled by Mitofusins Regulate Agrp Neuronal Activity and Diet-Induced Obesity

(2013) Marcelo O. Dietrich et al.   CELL

Mitochondrial Dynamics in the Regulation of Nutrient Utilization and Energy Expenditure

(2013) Marc Liesa et al.   Cell Metabolism

Melatonin Secretion and the Incidence of Type 2 Diabetes

(2013) Ciaran J. McMullan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Photoreceptor cells are major contributors to diabetes-induced oxidative stress and local inflammation in the retina

(2013) Y. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Update on animal models of diabetic retinopathy: from molecular approaches to mice and higher mammals

(2012) R. Robinson et al.   Disease Models & Mechanisms

Therapeutic efficacy of melatonin in reducing retinal damage in an experimental model of early type 2 diabetes in rats

(2012) Ezequiel M. Salido et al.   JOURNAL OF PINEAL RESEARCH

Consequences of oxidative stress in age-related macular degeneration

(2012) Stuart G. Jarrett et al.   MOLECULAR ASPECTS OF MEDICINE

The Mitochondrial Ca2+ Uniporter MCU Is Essential for Glucose-Induced ATP Increases in Pancreatic β-Cells

(2012) Andrei I. Tarasov et al.   PLoS One

Monitoring Intracellular Calcium Ion Dynamics in Hair Cell Populations with Fluo-4 AM

(2012) Kateri J. Spinelli et al.   PLoS One

Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis

(2012) D. Sebastian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial elongation during autophagy

(2011) Ligia C. Gomes et al.   Autophagy

Altered Mitochondrial Dynamics Contributes to Endothelial Dysfunction in Diabetes Mellitus

(2011) Sherene M. Shenouda et al.   CIRCULATION

Mitochondrial Calcium Signaling Mediates Rhythmic Extracellular ATP Accumulation in Suprachiasmatic Nucleus Astrocytes

(2011) J. F. Burkeen et al.   JOURNAL OF NEUROSCIENCE

The Melatonin MT1 Receptor Axis Modulates Mutant Huntingtin-Mediated Toxicity

(2011) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations

(2011) Carmen Venegas et al.   JOURNAL OF PINEAL RESEARCH

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

(2011) Diego De Stefani et al.   NATURE

Calcium uptake mechanisms of mitochondria

(2010) Jaime Santo-Domingo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondria: The calcium connection

(2010) Laura Contreras et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Exercise and Type 2 Diabetes: The American College of Sports Medicine and the American Diabetes Association: joint position statement

(2010) S. R. Colberg et al.   DIABETES CARE

Predominant cone photoreceptor dysfunction in a hyperglycaemic model of non-proliferative diabetic retinopathy

(2010) Y. Alvarez et al.   Disease Models & Mechanisms

Mitochondrial fission and fusion

(2010) Iain Scott et al.   Essays in Biochemistry

Color vision impairment in type 2 diabetes assessed by the D-15d test and the Cambridge Colour Test

(2010) Claudia Feitosa-Santana et al.   OPHTHALMIC AND PHYSIOLOGICAL OPTICS

High glucose enhances intracellular Ca2+ responses triggered by purinergic stimulation in retinal neurons and microglia

(2009) Tiago de Oliveira Simões Pereira et al.   BRAIN RESEARCH

Melatonin modulates visual function and cell viability in the mouse retina via the MT1 melatonin receptor

(2009) K. Baba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prolonged melatonin administration in 6-month-old Sprague-Dawley rats: metabolic alterations

(2008) B. Bojková et al.   ACTA PHYSIOLOGICA HUNGARICA

Alterations in mitochondrial function and cytosolic calcium induced by hyperglycemia are restored by mitochondrial transcription factor A in cardiomyocytes

(2008) Jorge Suarez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

High glucose changes extracellular adenosine triphosphate levels in rat retinal cultures

(2008) G. Costa et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Increased melatonin synthesis in pineal glands of rats in streptozotocin induced type 1 diabetes

(2008) Elmar Peschke et al.   JOURNAL OF PINEAL RESEARCH

Influence of dietary melatonin on photoreceptor survival in the rat retina: An ocular toxicity study

(2007) Allan F. Wiechmann et al.   EXPERIMENTAL EYE RESEARCH