Galangin Suppresses Renal Inflammation via the Inhibition of NF-κB, PI3K/AKT and NLRP3 in Uric Acid Treated NRK-52E Tubular Epithelial Cells

Phytochemical profiles, and antimicrobial and antioxidant activities of greater galangal [ Alpinia galanga (Linn.) Swartz.] flowers

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Scutellarin suppresses neuroinflammation via the inhibition of the AKT/NF-κB and p38/JNK pathway in LPS-induced BV-2 microglial cells

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Galangin ameliorates cisplatin-induced nephrotoxicity by attenuating oxidative stress, inflammation and cell death in mice through inhibition of ERK and NF-kappaB signaling

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Binding of anti-dsDNA antibodies to proximal tubular epithelial cells contributes to renal tubulointerstitial inflammation

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The antioxidant, cytotoxic, and antigenotoxic effects of galangin, puerarin, and ursolic acid in mammalian cells

(2016) Merve Bacanlı et al.   DRUG AND CHEMICAL TOXICOLOGY

Tenuigenin Prevents IL-1β-induced Inflammation in Human Osteoarthritis Chondrocytes by Suppressing PI3K/AKT/NF-κB Signaling Pathway

(2016) Chunlei Wang et al.   INFLAMMATION

Isolates of Alpinia officinarum Hance as COX-2 inhibitors: Evidence from anti-inflammatory, antioxidant and molecular docking studies

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Wogonoside protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NF-κB and NLRP3 inflammasome activation

(2015) Yang Sun et al.   BIOCHEMICAL PHARMACOLOGY

Evaluating the evidence for targeting FOXO3a in breast cancer: a systematic review

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TNF-related weak inducer of apoptosis (TWEAK) regulates junctional proteins in tubular epithelial cells via canonical NF-κB pathway and ERK activation

(2015) Sergio Berzal et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hyperuricemia-induced inflammasome and kidney diseases

(2015) Yoshitaka Isaka et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Uric Acid Produces an Inflammatory Response through Activation of NF-κB in the Hypothalamus: Implications for the Pathogenesis of Metabolic Disorders

(2015) Wenjie Lu et al.   Scientific Reports

Hemin inhibits NLRP3 inflammasome activation in sepsis-induced acute lung injury, involving heme oxygenase-1

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Interaction between systemic inflammation and renal tubular epithelial cells

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High fat diet feeding results in gender specific steatohepatitis and inflammasome activation

(2014) Michal Ganz   WORLD JOURNAL OF GASTROENTEROLOGY

The natural flavonoid galangin inhibits osteoclastic bone destruction and osteoclastogenesis by suppressing NF-κB in collagen-induced arthritis and bone marrow-derived macrophages

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β-Ionone attenuates LPS-induced pro-inflammatory mediators such as NO, PGE2 and TNF-α in BV2 microglial cells via suppression of the NF-κB and MAPK pathway

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NF-κB, Inflammation, and Metabolic Disease

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Anti-inflammatory function of arctiin by inhibiting COX-2 expression via NF-κB pathways

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Inhibition of TNF-α-Induced Inflammation by Andrographolide via Down-Regulation of the PI3K/Akt Signaling Pathway

(2011) Haw-Wen Chen et al.   JOURNAL OF NATURAL PRODUCTS

The role of the NLRP3 Inflammasome in the pathogenesis of airway disease

(2011) Mark A. Birrell et al.   PHARMACOLOGY & THERAPEUTICS

NLRP3 inflammasomes link inflammation and metabolic disease

(2011) Dominic De Nardo et al.   TRENDS IN IMMUNOLOGY

Caught red-handed: uric acid is an agent of inflammation

(2010) Yan Shi   JOURNAL OF CLINICAL INVESTIGATION

The NLRP3 Inflammasome Promotes Renal Inflammation and Contributes to CKD

(2010) A. Vilaysane et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Attenuation of oxidative stress and inflammation by gravinol in high glucose-exposed renal tubular epithelial cells

(2010) You Jung Kim et al.   TOXICOLOGY

Inhibition of PI3K-AKT-mTOR Signaling Sensitizes Melanoma Cells to Cisplatin and Temozolomide

(2008) Tobias Sinnberg et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Paricalcitol Inhibits Renal Inflammation by Promoting Vitamin D Receptor-Mediated Sequestration of NF- B Signaling

(2008) X. Tan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TLR4 Signaling Mediates Inflammation and Tissue Injury in Nephrotoxicity

(2008) B. Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY