Evaluating the evidence for targeting FOXO3a in breast cancer: a systematic review

MicroRNAs as regulatory elements in triple negative breast cancer

(2014) Melina-Theoni Gyparaki et al.   CANCER LETTERS

Downregulation of FOXO3a Promotes Tumor Metastasis and Is Associated with Metastasis-Free Survival of Patients with Clear Cell Renal Cell Carcinoma

(2014) D. Ni et al.   CLINICAL CANCER RESEARCH

Targeting PI3K/mTOR Overcomes Resistance to HER2-Targeted Therapy Independent of Feedback Activation of AKT

(2014) N. A. O'Brien et al.   CLINICAL CANCER RESEARCH

Antitumoral Activity of Indole-3-carbinol Cyclic tri- and Tetrameric Derivatives Mixture in Human Breast Cancer Cells: In Vitro and In Vivo Studies

(2013) Giorgio Brandi et al.   Anti-Cancer Agents in Medicinal Chemistry

Estrogen receptor alpha/beta ratio and estrogen receptor beta as predictors of endocrine therapy responsiveness–a randomized neoadjuvant trial comparison between anastrozole and tamoxifen for the treatment of postmenopausal breast cancer

(2013) Marcelo Madeira et al.   BMC CANCER

FOXO3a Is a Major Target of Inactivation by PI3K/AKT Signaling in Aggressive Neuroblastoma

(2013) E. E. Santo et al.   CANCER RESEARCH

The estrogen receptor α is the key regulator of the bifunctional role of FoxO3a transcription factor in breast cancer motility and invasiveness

(2013) Diego Sisci et al.   CELL CYCLE

Molecular Pathways: PI3K Pathway Targets in Triple-Negative Breast Cancers

(2013) V. Gordon et al.   CLINICAL CANCER RESEARCH

Foxo3a Expression Is a Prognostic Marker in Breast Cancer

(2013) Ying Jiang et al.   PLoS One

Decreased Expression of the FOXO3a Gene Is Associated with Poor Prognosis in Primary Gastric Adenocarcinoma Patients

(2013) Xiao-bo Yang et al.   PLoS One

Adaptation and learning of molecular networks as a description of cancer development at the systems-level: Potential use in anti-cancer therapies

(2013) Dávid M. Gyurkó et al.   SEMINARS IN CANCER BIOLOGY

Inhibition of metadherin sensitizes breast cancer cells to AZD6244

(2012) Xiaoli Kong et al.   CANCER BIOLOGY & THERAPY

Arsenic Trioxide-Induced Growth Arrest of Breast Cancer MCF-7 Cells Involving FOXO3a and IκB Kinase β Expression and Localization

(2012) Wenlou Liu et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Mutant p53 drives invasion in breast tumors through up-regulation of miR-155

(2012) P M Neilsen et al.   ONCOGENE

An Aqueous Extract of Fagonia cretica Induces DNA Damage, Cell Cycle Arrest and Apoptosis in Breast Cancer Cells via FOXO3a and p53 Expression

(2012) Matt Lam et al.   PLoS One

Upregulator of Cell Proliferation Predicts Poor Prognosis in Hepatocellular Carcinoma and Contributes to Hepatocarcinogenesis by Downregulating FOXO3a

(2012) Chan Xie et al.   PLoS One

Bimodal regulation of FoxO3 by AKT and 14-3-3

(2011) Melissa Dobson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

(2011) E C Ferber et al.   CELL DEATH AND DIFFERENTIATION

Knockdown of FLOT1 Impairs Cell Proliferation and Tumorigenicity in Breast Cancer through Upregulation of FOXO3a

(2011) C. Lin et al.   CLINICAL CANCER RESEARCH

18β-glycyrrhetinic acid induces apoptosis through modulation of Akt/FOXO3a/Bim pathway in human breast cancer MCF-7 cells

(2011) Gunjan Sharma et al.   JOURNAL OF CELLULAR PHYSIOLOGY

CCN1, a Candidate Target for Zoledronic Acid Treatment in Breast Cancer

(2011) I. Espinoza et al.   MOLECULAR CANCER THERAPEUTICS

FOXO3a represses VEGF expression through FOXM1-dependent and -independent mechanisms in breast cancer

(2011) C T Karadedou et al.   ONCOGENE

Feedback upregulation of HER3 (ErbB3) expression and activity attenuates antitumor effect of PI3K inhibitors

(2011) A. Chakrabarty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SZ-685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway

(2010) Gui'e Xie et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of FOXO3a Is Sufficient to Reverse Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase Inhibitor Chemoresistance in Human Cancer

(2010) Jer-Yen Yang et al.   CANCER RESEARCH

The AMPK-FoxO3A axis as a target for cancer treatment

(2010) Fulvio Chiacchiera et al.   CELL CYCLE

Cost-Effectiveness of Zoledronic Acid Plus Endocrine Therapy in Premenopausal Women With Hormone-Responsive Early Breast Cancer

(2010) Thomas E. Delea et al.   Clinical Breast Cancer

MicroRNA-155Regulates Cell Survival, Growth, and Chemosensitivity by TargetingFOXO3ain Breast Cancer

(2010) William Kong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Unregulated miR-96 Induces Cell Proliferation in Human Breast Cancer by Downregulating Transcriptional Factor FOXO3a

(2010) Huanxin Lin et al.   PLoS One

Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer

(2009) U. B. McGovern et al.   MOLECULAR CANCER THERAPEUTICS

The HER-2 Receptor and Breast Cancer: Ten Years of Targeted Anti-HER-2 Therapy and Personalized Medicine

(2009) J. S. Ross et al.   ONCOLOGIST

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

Withaferin A Causes FOXO3a- and Bim-Dependent Apoptosis and Inhibits Growth of Human Breast Cancer Cells In vivo

(2008) S. D. Stan et al.   CANCER RESEARCH

Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer

(2008) Cornelia Liedtke et al.   JOURNAL OF CLINICAL ONCOLOGY

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

(2008) Jer-Yen Yang et al.   NATURE CELL BIOLOGY

PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a)

(2008) B. M. Emerling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA