E6 proteins from high-risk HPV, low-risk HPV, and animal papillomaviruses activate the Wnt/β-catenin pathway through E6AP-dependent degradation of NHERF1

NHERF1 Between Promises and Hopes: Overview on Cancer and Prospective Openings

(2018) Matteo Centonze et al.   Translational Oncology

Human Papillomavirus E6 interaction with cellular PDZ domain proteins modulates YAP nuclear localization

(2018) Sydney Webb Strickland et al.   VIROLOGY

Worldwide burden of cancer attributable to HPV by site, country and HPV type

(2017) Catherine de Martel et al.   INTERNATIONAL JOURNAL OF CANCER

Role of the PDZ-scaffold protein NHERF1/EBP50 in cancer biology: from signaling regulation to clinical relevance

(2017) J Vaquero et al.   ONCOGENE

E6 proteins of α and β cutaneous HPV types differ in their ability to potentiate Wnt signaling

(2017) Sophia Sominsky et al.   VIROLOGY

The low-risk papillomaviruses

(2017) Nagayasu Egawa et al.   VIRUS RESEARCH

Association of papillomavirus E6 proteins with either MAML1 or E6AP clusters E6 proteins by structure, function, and evolutionary relatedness

(2017) Nicole Brimer et al.   PLoS Pathogens

Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53

(2016) Denise Martinez-Zapien et al.   NATURE

The Papillomavirus Episteme: a major update to the papillomavirus sequence database

(2016) Koenraad Van Doorslaer et al.   NUCLEIC ACIDS RESEARCH

High-Risk Human Papillomavirus E7 Proteins Target PTPN14 for Degradation

(2016) Elizabeth A. White et al.   mBio

NHERF1/EBP50 Suppresses Wnt-β-Catenin Pathway–Driven Intestinal Neoplasia

(2016) Maria-Magdalena Georgescu et al.   NEOPLASIA

The Human Papillomavirus E6 PDZ Binding Motif: From Life Cycle to Malignancy

(2015) Ketaki Ganti et al.   Viruses-Basel

Regulation of the Wnt/β-Catenin Signaling Pathway by Human Papillomavirus E6 and E7 Oncoproteins

(2015) Jesus Bello et al.   Viruses-Basel

Papillomavirus E6 Oncoproteins Take Common Structural Approaches to Solve Different Biological Problems

(2015) Scott Vande Pol   PLoS Pathogens

HPV16 E6 and E6AP differentially cooperate to stimulate or augment Wnt signaling

(2014) Sophia Sominsky et al.   VIROLOGY

Papillomavirus E6 PDZ Interactions Can Be Replaced by Repression of p53 To Promote Episomal Human Papillomavirus Genome Maintenance

(2013) N. Brimer et al.   JOURNAL OF VIROLOGY

Structural Basis for Hijacking of Cellular LxxLL Motifs by Papillomavirus E6 Oncoproteins

(2013) K. Zanier et al.   SCIENCE

The papillomavirus E7 proteins

(2013) Ann Roman et al.   VIROLOGY

Papillomavirus E6 oncoproteins

(2013) Scott B. Vande Pol et al.   VIROLOGY

Animal papillomaviruses

(2013) Annabel Rector et al.   VIROLOGY

Peptide Interactions Stabilize and Restructure Human Papillomavirus Type 16 E6 To Interact with p53

(2012) T. Ansari et al.   JOURNAL OF VIROLOGY

Cutaneous papillomavirus E6 oncoproteins associate with MAML1 to repress transactivation and NOTCH signaling

(2012) N Brimer et al.   ONCOGENE

Cutaneous  -human papillomavirus E6 proteins bind Mastermind-like coactivators and repress Notch signaling

(2012) M. J. A. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular transformation by human papillomaviruses: Lessons learned by comparing high- and low-risk viruses

(2012) Aloysius J. Klingelhutz et al.   VIROLOGY

E6 and E7 from Human Papillomavirus Type 16 Cooperate To Target the PDZ Protein Na/H Exchange Regulatory Factor 1

(2011) R. Accardi et al.   JOURNAL OF VIROLOGY

The E6 Oncoprotein from HPV16 Enhances the Canonical Wnt/ -Catenin Pathway in Skin Epidermis In Vivo

(2011) J. Bonilla-Delgado et al.   MOLECULAR CANCER RESEARCH

Direct interaction between NHERF1 and Frizzled regulates β-catenin signaling

(2010) D S Wheeler et al.   ONCOGENE

How viruses hijack cell regulation

(2010) Norman E. Davey et al.   TRENDS IN BIOCHEMICAL SCIENCES

A Conformational Switch in the Scaffolding Protein NHERF1 Controls Autoinhibition and Complex Formation

(2009) Shibani Bhattacharya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Papillomaviruses in the causation of human cancers — a brief historical account

(2009) Harald zur Hausen   VIROLOGY

HPV16 E6 augments Wnt signaling in an E6AP-dependent manner

(2009) Hava Lichtig et al.   VIROLOGY