Dynamic filopodial forces induce accumulation, damage, and plastic remodeling of 3D extracellular matrices

Engineered Tissue Folding by Mechanical Compaction of the Mesenchyme

(2018) Alex J. Hughes et al.   DEVELOPMENTAL CELL

Computation of forces from deformed visco-elastic biological tissues

(2018) José J Muñoz et al.   INVERSE PROBLEMS

A cytoskeletal clutch mediates cellular force transmission in a soft, three-dimensional extracellular matrix

(2017) Leanna M. Owen et al.   MOLECULAR BIOLOGY OF THE CELL

Stress-induced plasticity of dynamic collagen networks

(2017) Jihan Kim et al.   Nature Communications

YAP/TAZ link cell mechanics to Notch signalling to control epidermal stem cell fate

(2017) Antonio Totaro et al.   Nature Communications

Nanomechanics of Type I Collagen

(2016) Sameer Varma et al.   BIOPHYSICAL JOURNAL

Viscoplasticity Enables Mechanical Remodeling of Matrix by Cells

(2016) Sungmin Nam et al.   BIOPHYSICAL JOURNAL

Measurement of Elastic Modulus of Collagen Type I Single Fiber

(2016) Pavel Dutov et al.   PLoS One

Fiber networks amplify active stress

(2016) Pierre Ronceray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibrous nonlinear elasticity enables positive mechanical feedback between cells and ECMs

(2016) Matthew S. Hall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Strain-enhanced stress relaxation impacts nonlinear elasticity in collagen gels

(2016) Sungmin Nam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mean deformation metrics for quantifying 3D cell–matrix interactions without requiring information about matrix material properties

(2016) David A. Stout et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Morphogenesis of 3D vascular networks is regulated by tensile forces

(2016) Dekel Rosenfeld et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Matrix stiffening promotes a tumor vasculature phenotype

(2016) Francois Bordeleau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interplay of active processes modulates tension and drives phase transition in self-renewing, motor-driven cytoskeletal networks

(2016) Michael Mak et al.   Nature Communications

Mechanotransduction in cancer

(2016) LiKang Chin et al.   Current Opinion in Chemical Engineering

Matrix viscoplasticity and its shielding by active mechanics in microtissue models: experiments and mathematical modeling

(2016) Alan S. Liu et al.   Scientific Reports

Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway

(2015) Spencer C. Wei et al.   NATURE CELL BIOLOGY

Hydrogels with tunable stress relaxation regulate stem cell fate and activity

(2015) Ovijit Chaudhuri et al.   NATURE MATERIALS

Three-dimensional force microscopy of cells in biopolymer networks

(2015) Julian Steinwachs et al.   NATURE METHODS

Long-Range Force Transmission in Fibrous Matrices Enabled by Tension-Driven Alignment of Fibers

(2014) Hailong Wang et al.   BIOPHYSICAL JOURNAL

A Fast Iterative Digital Volume Correlation Algorithm for Large Deformations

(2014) E. Bar-Kochba et al.   EXPERIMENTAL MECHANICS

Inelastic behaviour of collagen networks in cell-matrix interactions and mechanosensation

(2014) H. Mohammadi et al.   Journal of the Royal Society Interface

Arp2/3 complex inhibitors adversely affect actin cytoskeleton remodeling in the cultured murine kidney collecting duct M-1 cells

(2013) Daria V. Ilatovskaya et al.   CELL AND TISSUE RESEARCH

Dimensions in cell migration

(2013) Andrew D Doyle et al.   CURRENT OPINION IN CELL BIOLOGY

Strain history dependence of the nonlinear stress response of fibrin and collagen networks

(2013) S. Munster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid disorganization of mechanically interacting systems of mammary acini

(2013) Q. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of Perfusable Microvascular Network Morphology Using a Multiculture Microfluidic System

(2013) Jordan A. Whisler et al.   TISSUE ENGINEERING PART C-METHODS

Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels

(2012) Yoojin Shin et al.   Nature Protocols

Cellular Traction Stresses Increase with Increasing Metastatic Potential

(2012) Casey M. Kraning-Rush et al.   PLoS One

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

(2011) Matthew W. Conklin et al.   AMERICAN JOURNAL OF PATHOLOGY

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

(2011) T. R. Cox et al.   Disease Models & Mechanisms

A Blind Spot in Confocal Reflection Microscopy: The Dependence of Fiber Brightness on Fiber Orientation in Imaging Biopolymer Networks

(2010) Louise M. Jawerth et al.   BIOPHYSICAL JOURNAL

Structural Hierarchy Governs Fibrin Gel Mechanics

(2010) Izabela K. Piechocka et al.   BIOPHYSICAL JOURNAL

A distinctive role for focal adhesion proteins in three-dimensional cell motility

(2010) Stephanie I. Fraley et al.   NATURE CELL BIOLOGY

Endothelial cell traction and ECM density influence both capillary morphogenesis and maintenance in 3-D

(2009) Ekaterina Kniazeva et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mechanics, malignancy, and metastasis: The force journey of a tumor cell

(2009) Sanjay Kumar et al.   CANCER AND METASTASIS REVIEWS

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Non-Linear Elasticity of Extracellular Matrices Enables Contractile Cells to Communicate Local Position and Orientation

(2009) Jessamine P. Winer et al.   PLoS One

Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues

(2009) W. R. Legant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational Analysis of Viscoelastic Properties of Crosslinked Actin Networks

(2009) Taeyoon Kim et al.   PLoS Computational Biology

Biophysics of Catch Bonds

(2008) Wendy E. Thomas et al.   Annual Review of Biophysics

Contact Guidance Mediated Three-Dimensional Cell Migration is Regulated by Rho/ROCK-Dependent Matrix Reorganization

(2008) Paolo P. Provenzano et al.   BIOPHYSICAL JOURNAL

Stress-Strain Experiments on Individual Collagen Fibrils

(2008) Zhilei L. Shen et al.   BIOPHYSICAL JOURNAL

A Balance of Substrate Mechanics and Matrix Chemistry Regulates Endothelial Cell Network Assembly

(2008) Joseph P. Califano et al.   Cellular and Molecular Bioengineering

Nanomechanics of collagen fibrils under varying cross-link densities: Atomistic and continuum studies

(2007) Markus J. Buehler   Journal of the Mechanical Behavior of Biomedical Materials