Cellular labeling of endogenous retrovirus replication (CLEVR) reveals de novo insertions of the gypsy retrotransposable element in cell culture and in both neurons and glial cells of aging fruit flies

L1 drives IFN in senescent cells and promotes age-associated inflammation

(2019) Marco De Cecco et al.   NATURE

The Retrotransposon storm and the dangers of a Collyer's genome

(2018) Josh Dubnau   CURRENT OPINION IN GENETICS & DEVELOPMENT

Engrailed homeoprotein blocks degeneration in adult dopaminergic neurons through LINE‐1 repression

(2018) François‐Xavier Blaudin de Thé et al.   EMBO JOURNAL

L1 retrotransposition is a common feature of mammalian hepatocarcinogenesis

(2018) Stephanie N. Schauer et al.   GENOME RESEARCH

Pathogenic tau-induced piRNA depletion promotes neuronal death through transposable element dysregulation in neurodegenerative tauopathies

(2018) Wenyan Sun et al.   NATURE NEUROSCIENCE

L1 Retrotransposon Heterogeneity in Ovarian Tumor Cell Evolution

(2018) Thu H.M. Nguyen et al.   Cell Reports

Tau Activates Transposable Elements in Alzheimer’s Disease

(2018) Caiwei Guo et al.   Cell Reports

Retrotransposon-induced mosaicism in the neural genome

(2018) Gabriela O. Bodea et al.   Open Biology

Mobile DNA in Health and Disease

(2017) Haig H. Kazazian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human transposon insertion profiling: Analysis, visualization and identification of somatic LINE-1 insertions in ovarian cancer

(2017) Zuojian Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piwi Is Required to Limit Exhaustion of Aging Somatic Stem Cells

(2017) Pedro Sousa-Victor et al.   Cell Reports

Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS

(2017) Lisa Krug et al.   PLoS Genetics

Resolving the prevalence of somatic transposition in Drosophila

(2017) Christoph D Treiber et al.   eLife

Engineered LINE-1 retrotransposition in nondividing human neurons

(2016) Angela Macia et al.   GENOME RESEARCH

Somatically Acquired LINE-1 Insertions in Normal Esophagus Undergo Clonal Expansion in Esophageal Squamous Cell Carcinoma

(2016) Tara T. Doucet-O'Hare et al.   HUMAN MUTATION

The Complete Genome Sequences, Unique Mutational Spectra, and Developmental Potency of Adult Neurons Revealed by Cloning

(2016) Jennifer L. Hazen et al.   NEURON

Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span inDrosophila

(2016) Jason G. Wood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan

(2016) Brian C. Jones et al.   Nature Communications

Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells

(2016) Sabine Klawitter et al.   Nature Communications

Environment-driven somatic mosaicism in brain disorders

(2016) Tracy A. Bedrosian et al.   Genome Medicine

Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme

(2016) Patricia E. Carreira et al.   Mobile DNA

Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues

(2016) Marco De Cecco et al.   Aging-US

Ubiquitous L1 Mosaicism in Hippocampal Neurons

(2015) Kyle R. Upton et al.   CELL

Primate-Specific ORF0 Contributes to Retrotransposon-Mediated Diversity

(2015) Ahmet M. Denli et al.   CELL

What might retrotransposons teach us about aging?

(2015) Patrick H. Maxwell   CURRENT GENETICS

p53 genes function to restrain mobile elements

(2015) Annika Wylie et al.   GENES & DEVELOPMENT

LINE-1 expression and retrotransposition in Barrett’s esophagus and esophageal carcinoma

(2015) Tara T. Doucet-O'Hare et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Somatic mutation in single human neurons tracks developmental and transcriptional history

(2015) M. A. Lodato et al.   SCIENCE

Human endogenous retrovirus-K contributes to motor neuron disease

(2015) Wenxue Li et al.   Science Translational Medicine

L1 Retrotransposons and Somatic Mosaicism in the Brain

(2014) Sandra R. Richardson et al.   Annual Review of Genetics

The enemy within: endogenous retroelements and autoimmune disease

(2014) Hannah E Volkman et al.   NATURE IMMUNOLOGY

Carrier of Wingless (Cow), a Secreted Heparan Sulfate Proteoglycan, Promotes Extracellular Transport of Wingless

(2014) Yung-Heng Chang et al.   PLoS One

Endogenous Retrotransposition Activates Oncogenic Pathways in Hepatocellular Carcinoma

(2013) Ruchi Shukla et al.   CELL

L1 retrotransposons, cancer stem cells and oncogenesis

(2013) Patricia E. Carreira et al.   FEBS Journal

The Role of Transposable Elements in Health and Diseases of the Central Nervous System

(2013) M. T. Reilly et al.   JOURNAL OF NEUROSCIENCE

Activation of transposable elements during aging and neuronal decline in Drosophila

(2013) Wanhe Li et al.   NATURE NEUROSCIENCE

Transposition-Driven Genomic Heterogeneity in the Drosophila Brain

(2013) P. N. Perrat et al.   SCIENCE

RNA editing regulates transposon-mediated heterochromatic gene silencing

(2013) Yiannis A. Savva et al.   Nature Communications

Active Transposition in Genomes

(2012) Cheng Ran Lisa Huang et al.   Annual Review of Genetics

Single-Neuron Sequencing Analysis of L1 Retrotransposition and Somatic Mutation in the Human Brain

(2012) Gilad D. Evrony et al.   CELL

Extensive somatic L1 retrotransposition in colorectal tumors

(2012) S. Solyom et al.   GENOME RESEARCH

Studies of endogenous retroviruses reveal a continuing evolutionary saga

(2012) Jonathan P. Stoye   NATURE REVIEWS MICROBIOLOGY

Transposable Elements in TDP-43-Mediated Neurodegenerative Disorders

(2012) Wanhe Li et al.   PLoS One

Retrotransposon activation contributes to fragile X premutation rCGG-mediated neurodegeneration

(2011) H. Tan et al.   HUMAN MOLECULAR GENETICS

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

(2011) Hiroki Kaneko et al.   NATURE

Somatic retrotransposition alters the genetic landscape of the human brain

(2011) J. Kenneth Baillie et al.   NATURE

Retrotransposition is associated with genome instability during chronological aging

(2011) P. H. Maxwell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retrotransposition of R2 elements in somatic nuclei during the early development of Drosophila

(2011) Michael T Eickbush et al.   Mobile DNA

Identification of active loci of a human endogenous retrovirus in neurons of patients with amyotrophic lateral sclerosis

(2010) Renée Douville et al.   ANNALS OF NEUROLOGY

Refinement of Tools for Targeted Gene Expression in Drosophila

(2010) B. D. Pfeiffer et al.   GENETICS

L1 retrotransposition in neurons is modulated by MeCP2

(2010) Alysson R. Muotri et al.   NATURE

Cis-interactions between Notch and Delta generate mutually exclusive signalling states

(2010) David Sprinzak et al.   NATURE

Environmental influence on L1 retrotransposons in the adult hippocampus

(2009) Alysson R. Muotri et al.   HIPPOCAMPUS

Identification of Domains Responsible for Ubiquitin-Dependent Degradation of dMyc by Glycogen Synthase Kinase 3  and Casein Kinase 1 Kinases

(2009) M. Galletti et al.   MOLECULAR AND CELLULAR BIOLOGY

L1 retrotransposition in human neural progenitor cells

(2009) Nicole G. Coufal et al.   NATURE

Endogenous RNA Interference Provides a Somatic Defense against Drosophila Transposons

(2008) Wei-Jen Chung et al.   CURRENT BIOLOGY

The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control

(2008) Lei Zhang et al.   DEVELOPMENTAL CELL

Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells

(2008) Yoshinori Kawamura et al.   NATURE

An endogenous small interfering RNA pathway in Drosophila

(2008) Benjamin Czech et al.   NATURE

Endogenous siRNAs Derived from Transposons and mRNAs in Drosophila Somatic Cells

(2008) M. Ghildiyal et al.   SCIENCE