Carfilzomib enhances cisplatin-induced apoptosis in SK-N-BE(2)-M17 human neuroblastoma cells

Busulfan and melphalan versus carboplatin, etoposide, and melphalan as high-dose chemotherapy for high-risk neuroblastoma (HR-NBL1/SIOPEN): an international, randomised, multi-arm, open-label, phase 3 trial

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Endoplasmic reticulum-mitochondrial crosstalk: a novel role for the mitochondrial peptide humanin

(2017) DavidR Hinton et al.   Neural Regeneration Research

A phase 1/2 study of carfilzomib in Japanese patients with relapsed and/or refractory multiple myeloma

(2016) Takashi Watanabe et al.   BRITISH JOURNAL OF HAEMATOLOGY

Carfilzomib Triggers Cell Death in Chronic Lymphocytic Leukemia by Inducing Proapoptotic and Endoplasmic Reticulum Stress Responses

(2016) B. Lamothe et al.   CLINICAL CANCER RESEARCH

Carfilzomib induces G2/M cell cycle arrest in human endometrial cancer cells via upregulation of p21Waf1/Cip1 and p27Kip1

(2016) Yuanyuan Zhou et al.   Taiwanese Journal of Obstetrics & Gynecology

Neuroblastoma: Molecular Pathogenesis and Therapy

(2015) Chrystal U. Louis et al.   Annual Review of Medicine

Carfilzomib is an effective anticancer agent in anaplastic thyroid cancer

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Mitochondrial thioredoxin reductase regulates major cytotoxicity pathways of proteasome inhibitors in multiple myeloma cells

(2015) E E Fink et al.   LEUKEMIA

Proteasome inhibitor carfilzomib interacts synergistically with histone deacetylase inhibitor vorinostat in Jurkat T-leukemia cells

(2014) Minjie Gao et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Enhanced anti-colorectal cancer effects of carfilzomib combined with CPT-11 via downregulation of nuclear factor-κB in vitro and in vivo

(2014) WEIWEI TANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Carfilzomib demonstrates broad anti-tumor activity in pre-clinical non-small cell and small cell lung cancer models

(2014) Amanda F Baker et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Carfilzomib

(2013) K. M. Kortuem et al.   BLOOD

In VitroandIn VivoTherapeutic Efficacy of Carfilzomib in Mantle Cell Lymphoma: Targeting the Immunoproteasome

(2013) Liang Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Panobinostat Synergistically Enhances the Cytotoxic Effects of Cisplatin, Doxorubicin or Etoposide on High-Risk Neuroblastoma Cells

(2013) Guan Wang et al.   PLoS One

Caspase Functions in Cell Death and Disease

(2013) D. R. McIlwain et al.   Cold Spring Harbor Perspectives in Biology

Apicidin induces endoplasmic reticulum stress- and mitochondrial dysfunction-associated apoptosis via phospholipase Cγ1- and Ca2+-dependent pathway in mouse Neuro-2a neuroblastoma cells

(2012) Ji Hyun Choi et al.   APOPTOSIS

The next generation proteasome inhibitors carfilzomib and oprozomib activate prosurvival autophagy via induction of the unfolded protein response and ATF4

(2012) Yan Zang et al.   Autophagy

Carfilzomib and ONX 0912 Inhibit Cell Survival and Tumor Growth of Head and Neck Cancer and Their Activities Are Enhanced by Suppression of Mcl-1 or Autophagy

(2012) Y. Zang et al.   CLINICAL CANCER RESEARCH

Association of Age at Diagnosis and Genetic Mutations in Patients With Neuroblastoma

(2012) Nai-Kong V. Cheung   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A review of the mammalian unfolded protein response

(2011) Anirikh Chakrabarti et al.   BIOTECHNOLOGY AND BIOENGINEERING

Luteolin induces apoptosis through endoplasmic reticulum stress and mitochondrial dysfunction in Neuro-2a mouse neuroblastoma cells

(2011) A Young Choi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects

(2011) Ana-Maria Florea et al.   Cancers

Recent Advances in Neuroblastoma

(2010) John M. Maris   NEW ENGLAND JOURNAL OF MEDICINE

Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome

(2009) F. Parlati et al.   BLOOD

Recent advances in neuroblastoma

(2009) Kanika A Bowen et al.   CURRENT OPINION IN PEDIATRICS

Targeting the extrinsic apoptosis pathway in cancer

(2008) Avi Ashkenazi   CYTOKINE & GROWTH FACTOR REVIEWS