A Lipophilic Fucoxanthin-Rich Phaeodactylum tricornutum Extract Ameliorates Effects of Diet-Induced Obesity in C57BL/6J Mice

Antihyperlipidemic effect of a Rhamnus alaternus leaf extract in Triton-induced hyperlipidemic rats and human HepG2 cells

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Anti-inflammatory effects of Phaeodactylum tricornutum extracts on human blood mononuclear cells and murine macrophages

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Fucoxanthin ameliorates hyperglycemia, hyperlipidemia and insulin resistance in diabetic mice partially through IRS-1/PI3K/Akt and AMPK pathways

(2018) Yiping Zhang et al.   Journal of Functional Foods

Bioavailability and Safety of Nutrients from the Microalgae Chlorella vulgaris, Nannochloropsis oceanica and Phaeodactylum tricornutum in C57BL/6 Mice

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Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity

(2017) Brittney R. Coats et al.   Cell Reports

Microalga Phaeodactylum tricornutum in feed for Atlantic salmon (Salmo salar) —Effect on nutrient digestibility, growth and utilization of feed

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Emerging evidence for beneficial macrophage functions in atherosclerosis and obesity-induced insulin resistance

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Marine Algae as a Potential Source for Anti-Obesity Agents

(2016) Chu Wan-Loy et al.   Marine Drugs

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(2016) Bàrbara Reynés et al.   Journal of Functional Foods

Evaluation of the anti-obesity effect of the microalga Phaeodactylum tricornutum

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Improved metabolic regulation is associated with retinoblastoma protein gene haploinsufficiency in mice

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Mitofusin 2 as a Driver That Controls Energy Metabolism and Insulin Signaling

(2015) Antonio Zorzano et al.   ANTIOXIDANTS & REDOX SIGNALING

CD36 is indispensable for thermogenesis under conditions of fasting and cold stress

(2015) Mirasari Putri et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of Mest/Peg1 gene expression as a predictive biomarker of adipose tissue expansion sensitive to dietary anti-obesity interventions

(2015) Anja Voigt et al.   Genes and Nutrition

Nutraceutical Effects of Fucoxanthin for Obesity and Diabetes Therapy: A Review

(2015) Hayato Maeda   Journal of Oleo Science

Fucoxanthinol, Metabolite of Fucoxanthin, Improves Obesity-Induced Inflammation in Adipocyte Cells

(2015) Hayato Maeda et al.   Marine Drugs

Dependence of Brown Adipose Tissue Function on CD36-Mediated Coenzyme Q Uptake

(2015) Courtney M. Anderson et al.   Cell Reports

Identification of Mest/Peg1 gene expression as a predictive biomarker of adipose tissue expansion sensitive to dietary anti-obesity interventions

(2015) Anja Voigt et al.   Genes and Nutrition

Therapeutic Phytogenic Compounds for Obesity and Diabetes

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Dietary Fucoxanthin Increases Metabolic Rate and Upregulated mRNA Expressions of the PGC-1alpha Network, Mitochondrial Biogenesis and Fusion Genes in White Adipose Tissues of Mice

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Antiobesity Effects of the Ethanol Extract ofLaminaria japonicaAreshoung in High-Fat-Diet-Induced Obese Rat

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Antioxidant effect of Phaeodactylum tricornutum in mice fed high-fat diet

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(2013) Alexander Bartelt et al.   Nature Reviews Endocrinology

A Potential Commercial Source of Fucoxanthin Extracted from the Microalga Phaeodactylum tricornutum

(2012) Sang Min Kim et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Pharmacological and nutritional agents promoting browning of white adipose tissue

(2012) M. Luisa Bonet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

EPA and DHA Differentially Affect In Vitro Inflammatory Cytokine Release by Peripheral Blood Mononuclear Cells from Alzheimer’s Patients

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Fucoxanthin promotes translocation and induction of glucose transporter 4 in skeletal muscles of diabetic/obese KK-Ay mice

(2012) Sho Nishikawa et al.   PHYTOMEDICINE

Influence of Drying and Storage on Lipid and Carotenoid Stability of the MicroalgaPhaeodactylum tricornutum

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(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Fucoxanthin regulates adipocytokine mRNA expression in white adipose tissue of diabetic/obese KK-Ay mice

(2010) Masashi Hosokawa et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Fucoxanthin-rich seaweed extract suppresses body weight gain and improves lipid metabolism in high-fat-fed C57BL/6J mice

(2010) Seon-Min Jeon et al.   Biotechnology Journal

Fucoxanthin supplementation improves plasma and hepatic lipid metabolism and blood glucose concentration in high-fat fed C57BL/6N mice

(2010) Myoung-Nam Woo et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Regional impact of adipose tissue morphology on the metabolic profile in morbid obesity

(2010) J. Hoffstedt et al.   DIABETOLOGIA

Fucoxanthin inhibits the inflammatory response by suppressing the activation of NF-κB and MAPKs in lipopolysaccharide-induced RAW 264.7 macrophages

(2010) Kil-Nam Kim et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Evaluation of anti-inflammatory effect of fucoxanthin isolated from brown algae in lipopolysaccharide-stimulated RAW 264.7 macrophages

(2010) Soo-Jin Heo et al.   FOOD AND CHEMICAL TOXICOLOGY

Thermogenic ingredients and body weight regulation

(2010) R Hursel et al.   INTERNATIONAL JOURNAL OF OBESITY

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

(2010) Patrick Seale et al.   JOURNAL OF CLINICAL INVESTIGATION

Keto-Carotenoids Are the Major Metabolites of Dietary Lutein and Fucoxanthin in Mouse Tissues

(2010) Lina Yonekura et al.   JOURNAL OF NUTRITION

The distribution and accumulation of fucoxanthin and its metabolites after oral administration in mice

(2009) Takashi Hashimoto et al.   BRITISH JOURNAL OF NUTRITION

Suppressive effects of the marine carotenoids, fucoxanthin and fucoxanthinol on triglyceride absorption in lymph duct-cannulated rats

(2009) Megumi Matsumoto et al.   EUROPEAN JOURNAL OF NUTRITION

Anti-obesity and anti-diabetic effects of fucoxanthin on diet-induced obesity conditions in a murine model

(2009) Maeda   Molecular Medicine Reports

Anti-obese property of fucoxanthin is partly mediated by altering lipid-regulating enzymes and uncoupling proteins of visceral adipose tissue in mice

(2009) Myoung-Nam Woo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

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(2008) Donald B Jump   CURRENT OPINION IN LIPIDOLOGY

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(2008) Victor A. Zammit   IUBMB LIFE