Selective cell death of latently HIV-infected CD4+ T cells mediated by autosis inducing nanopeptides

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Dysregulation of apoptosis and autophagy gene expression in peripheral blood mononuclear cells of efficiently treated HIV-infected patients

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Induction of a Na+/K+-ATPase-Dependent Form of Autophagy Triggers Preferential Cell Death of Human Immunodeficiency Virus Type-1-Infected Macrophages

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Getting the “Kill” into “Shock and Kill”: Strategies to Eliminate Latent HIV

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Anti-apoptotic Protein BIRC5 Maintains Survival of HIV-1-Infected CD4 + T Cells

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Induction of autophagy by PI3K/MTOR and PI3K/MTOR/BRD4 inhibitors suppresses HIV-1 replication

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CD4 T cell autophagy is integral to memory maintenance

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Cardiac glycoside/aglycones inhibit HIV-1 gene expression by a mechanism requiring MEK1/2-ERK1/2 signaling

(2018) Raymond W. Wong et al.   Scientific Reports

T-Cell-Mimicking Nanoparticles Can Neutralize HIV Infectivity

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SMAC Mimetics Induce Autophagy-Dependent Apoptosis of HIV-1-Infected Resting Memory CD4+ T Cells

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(2017) Kazuhisa Yoshimura   JOURNAL OF INFECTION AND CHEMOTHERAPY

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Novel assay reveals a large, inducible, replication-competent HIV-1 reservoir in resting CD4+ T cells

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The Latent Reservoir for HIV-1: How Immunologic Memory and Clonal Expansion Contribute to HIV-1 Persistence

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The mixed lineage kinase-3 inhibitor URMC-099 improves therapeutic outcomes for long-acting antiretroviral therapy

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Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

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CRISPR/Cas9-Derived Mutations Both Inhibit HIV-1 Replication and Accelerate Viral Escape

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Pharmacodynamics of long-acting folic acid-receptor targeted ritonavir-boosted atazanavir nanoformulations

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Cell death by autophagy: emerging molecular mechanisms and implications for cancer therapy

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Application of gene-editing technologies to HIV-1

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Human Immunodeficiency Virus Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration

(2015) Grant R. Campbell et al.   PLoS Pathogens

Autophagy plays an important role in the containment of HIV-1 in nonprogressor-infected patients

(2014) Roberta Nardacci et al.   Autophagy

Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice

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Endosomal Trafficking of Nanoformulated Antiretroviral Therapy Facilitates Drug Particle Carriage and HIV Clearance

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Quantitation of Replication-Competent HIV-1 in Populations of Resting CD4+ T Cells

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Autophagy is essential for effector CD8+ T cell survival and memory formation

(2014) Xiaojin Xu et al.   NATURE IMMUNOLOGY

Zinc-finger nucleases make the cut in HIV

(2014) Brian Owens   NATURE REVIEWS DRUG DISCOVERY

RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection

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Autophagy as a defence against intracellular pathogens

(2013) Tom Wileman   Essays in Biochemistry

A novel cell-based high-throughput screen for inhibitors of HIV-1 gene expression and budding identifies the cardiac glycosides

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The Presence of HIV-1 Tat Protein Second Exon Delays Fas Protein-mediated Apoptosis in CD4+T Lymphocytes

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(2013) Sanae Shoji-Kawata et al.   NATURE

The autophagosome: origins unknown, biogenesis complex

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Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

(2013) Y. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Newer Gene Editing Technologies toward HIV Gene Therapy

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Digoxin Suppresses HIV-1 Replication by Altering Viral RNA Processing

(2013) Raymond W. Wong et al.   PLoS Pathogens

Rapid Quantification of the Latent Reservoir for HIV-1 Using a Viral Outgrowth Assay

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Anti-apoptotic mechanisms of HIV: lessons and novel approaches to curing HIV

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Production of Interferon α by Human Immunodeficiency Virus Type 1 in Human Plasmacytoid Dendritic Cells Is Dependent on Induction of Autophagy

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Shock and kill

(2012) Steven G. Deeks   NATURE

Authorsʼ reply to correspondence by Le and Farrar

(2011) Tae-Wook Chun et al.   AIDS

Hormonally Active Vitamin D3 (1α,25-Dihydroxycholecalciferol) Triggers Autophagy in Human Macrophages That Inhibits HIV-1 Infection

(2011) Grant R. Campbell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy Is Increased in Postmortem Brains of Persons With HIV-1-Associated Encephalitis

(2011) Dejiang Zhou et al.   JOURNAL OF INFECTIOUS DISEASES

CD4+ T Cell Depletion in Human Immunodeficiency Virus (HIV) Infection: Role of Apoptosis

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Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication

(2010) Tae-Wook Chun et al.   AIDS

Half-Antibody Functionalized Lipid−Polymer Hybrid Nanoparticles for Targeted Drug Delivery to Carcinoembryonic Antigen Presenting Pancreatic Cancer Cells

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Human immunodeficiency virus type-1 infection inhibits autophagy

(2009) Dejiang Zhou et al.   AIDS

New insights on the role of apoptosis and autophagy in HIV pathogenesis

(2009) M.-L. Gougeon et al.   APOPTOSIS

Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages

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FLIP-mediated autophagy regulation in cell death control

(2009) Jong-Soo Lee et al.   NATURE CELL BIOLOGY

Self-Assembled Lipid−Polymer Hybrid Nanoparticles: A Robust Drug Delivery Platform

(2008) Liangfang Zhang et al.   ACS Nano