Unconjugated bilirubin alleviates experimental ulcerative colitis by regulating intestinal barrier function and immune inflammation

The bile acids, deoxycholic acid and ursodeoxycholic acid, regulate colonic epithelial wound healing

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Understanding and Preventing the Global Increase of Inflammatory Bowel Disease

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Unconjugated bilirubin ameliorates the inflammation and digestive protease increase in TNBS-induced colitis

(2017) Jin-An Zhou et al.   Molecular Medicine Reports

Reduced total serum bilirubin levels are associated with ulcerative colitis

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Probiotic Bacteria Lactobacillus and Bifidobacterium Attenuate Inflammation in Dextran Sulfate Sodium-Induced Experimental Colitis in Mice

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Bilirubin Nanoparticles as a Nanomedicine for Anti-inflammation Therapy

(2016) Yonghyun Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome

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Bilirubin prevents acute DSS-induced colitis by inhibiting leukocyte infiltration and suppressing upregulation of inducible nitric oxide synthase

(2015) Stephen D. Zucker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Role of bilirubin in digestive proteases inactivation in the lower intestine

(2015) Kangkang Zhou et al.   DIGESTIVE AND LIVER DISEASE

Gut Microbiota and Energy Expenditure in Health and Obesity

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The global burden of IBD: from 2015 to 2025

(2015) Gilaad G. Kaplan   Nature Reviews Gastroenterology & Hepatology

Immunopathogenesis of IBD: current state of the art

(2015) Heitor S. P. de Souza et al.   Nature Reviews Gastroenterology & Hepatology

Proteases and small intestinal barrier function in health and disease

(2014) Paolo Giuffrida et al.   CURRENT OPINION IN GASTROENTEROLOGY

Unconjugated Bilirubin Mediates Heme Oxygenase-1–Induced Vascular Benefits in Diabetic Mice

(2014) Jian Liu et al.   DIABETES

Expression and implication of toll-like receptors TLR2, TLR4 and TLR9 in colonic mucosa of patients with ulcerative colitis

(2014) Yan Tan et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

TLR4 regulates IFN-γ and IL-17 production by both thymic and induced Foxp3+ Tregs during intestinal inflammation

(2014) Anthony T. Cao et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Contribution of TLR signaling to the pathogenesis of colitis-associated cancer in inflammatory bowel disease

(2014) Ferenc Sipos   WORLD JOURNAL OF GASTROENTEROLOGY

Intestinal barrier in inflammatory bowel disease

(2014) Lena Antoni   WORLD JOURNAL OF GASTROENTEROLOGY

Bilirubin mediated oxidative stress involves antioxidant response activation via Nrf2 pathway

(2013) Mohammed Qaisiya et al.   CELLULAR SIGNALLING

Incidence and Phenotype of Inflammatory Bowel Disease Based on Results From the Asia-Pacific Crohn's and Colitis Epidemiology Study

(2013) Siew C. Ng et al.   GASTROENTEROLOGY

Bilirubin-Induced Neurologic Damage — Mechanisms and Management Approaches

(2013) Jon F. Watchko et al.   NEW ENGLAND JOURNAL OF MEDICINE

Proteases and the gut barrier

(2012) Paolo Biancheri et al.   CELL AND TISSUE RESEARCH

Effect of PEG molecular weight and linking chemistry on the biological activity and thermal stability of PEGylated trypsin

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