DNA threads released by activated CD4+ T lymphocytes provide autocrine costimulation

Mitochondrial DNA as an inflammatory mediator in cardiovascular diseases

(2018) Hiroyuki Nakayama et al.   BIOCHEMICAL JOURNAL

Roles of PAD4 and NETosis in Experimental Atherosclerosis and Arterial InjuryNovelty and Significance

(2018) Grégory Franck et al.   CIRCULATION RESEARCH

Cerebrospinal fluid mitochondrial DNA levels in patients with multiple sclerosis

(2018) Nicolas Fissolo et al.   Multiple Sclerosis Journal

Macrophage extracellular trap formation promoted by platelet activation is a key mediator of rhabdomyolysis-induced acute kidney injury

(2018) Koshu Okubo et al.   NATURE MEDICINE

Lymphocytes eject interferogenic mitochondrial DNA webs in response to CpG and non-CpG oligodeoxynucleotides of class C

(2018) Björn Ingelsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cerebrospinal fluid mitochondrial DNA levels in patients with multiple sclerosis

(2018) Nicolas Fissolo et al.   Multiple Sclerosis Journal

Degraded Mitochondrial DNA is a Newly Identified Subtype of the Damage Associated Molecular Pattern (DAMP) Family and Possible Trigger of Neurodegeneration

(2018) Alex Mathew et al.   JOURNAL OF ALZHEIMERS DISEASE

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation

(2018) Zhenyu Zhong et al.   NATURE

Increased levels of cell-free mitochondrial DNA in the cerebrospinal fluid of patients with multiple sclerosis

(2017) Kristin N. Varhaug et al.   MITOCHONDRION

Cerebrospinal fluid mtDNA concentration is elevated in multiple sclerosis disease and responds to treatment

(2017) Cyra E Leurs et al.   Multiple Sclerosis Journal

An emerging role for neutrophil extracellular traps in noninfectious disease

(2017) Selina K Jorch et al.   NATURE MEDICINE

Cerebrospinal fluid mtDNA concentration is elevated in multiple sclerosis disease and responds to treatment

(2017) Cyra E Leurs et al.   Multiple Sclerosis Journal

Oxidized mitochondrial nucleoids released by neutrophils drive type I interferon production in human lupus

(2016) Simone Caielli et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

(2016) Christian Lood et al.   NATURE MEDICINE

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells

(2016) G. Arbore et al.   SCIENCE

Neutrophil-related factors as biomarkers in EAE and MS

(2015) Julie M. Rumble et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunology of Relapse and Remission in Multiple Sclerosis

(2014) Lawrence Steinman   Annual Review of Immunology

Microglia and motor neurons during disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis: changes in arginase1 and inducible nitric oxide synthase

(2014) Katherine E Lewis et al.   Journal of Neuroinflammation

Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling

(2013) Laura A. Sena et al.   IMMUNITY

Prolactin Is Not Required for the Development of Severe Chronic Experimental Autoimmune Encephalomyelitis

(2013) M. Costanza et al.   JOURNAL OF IMMUNOLOGY

The Disease-Ameliorating Function of Autoregulatory CD8 T Cells Is Mediated by Targeting of Encephalitogenic CD4 T Cells in Experimental Autoimmune Encephalomyelitis

(2013) S. B. Ortega et al.   JOURNAL OF IMMUNOLOGY

Protective effect of mitochondria-targeted antioxidants in an acute bacterial infection

(2013) E. Y. Plotnikov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity

(2012) S. Sangaletti et al.   BLOOD

Protective effect of an elastase inhibitor in a neuromyelitis optica-like disease driven by a peptide of myelin oligodendroglial glycoprotein

(2012) Katja Herges et al.   Multiple Sclerosis Journal

CpG and Non-CpG Oligodeoxynucleotides Directly Costimulate Mouse and Human CD4+ T Cells through a TLR9- and MyD88-Independent Mechanism

(2011) A. Landrigan et al.   JOURNAL OF IMMUNOLOGY

Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense

(2008) Shida Yousefi et al.   NATURE MEDICINE