Structure-guided function discovery of an NRPS-like glycine betaine reductase for choline biosynthesis in fungi

Carboxylic acid reductase enzymes (CARs)

(2018) Margit Winkler   CURRENT OPINION IN CHEMICAL BIOLOGY

Biosynthesis of Long-Chain N-Acyl Amide by a Truncated Polyketide Synthase–Nonribosomal Peptide Synthetase Hybrid Megasynthase in Fungi

(2018) Yang Hai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The birth, evolution and death of metabolic gene clusters in fungi

(2018) Antonis Rokas et al.   NATURE REVIEWS MICROBIOLOGY

Structures of carboxylic acid reductase reveal domain dynamics underlying catalysis

(2017) Deepankar Gahloth et al.   Nature Chemical Biology

Colibactin assembly line enzymes use S-adenosylmethionine to build a cyclopropane ring

(2017) Li Zha et al.   Nature Chemical Biology

Nonribosomal biosynthesis of backbone-modified peptides

(2017) David L. Niquille et al.   Nature Chemistry

Microbial production of scent and flavor compounds

(2016) Austin L Carroll et al.   CURRENT OPINION IN BIOTECHNOLOGY

Biotechnological Production of Methyl-Branched Aldehydes

(2016) Marco Alexander Fraatz et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Biosynthesis of Strained Piperazine Alkaloids: Uncovering the Concise Pathway of Herquline A

(2016) Xia Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Modular and selective biosynthesis of gasoline-range alkanes

(2016) Micah J. Sheppard et al.   METABOLIC ENGINEERING

Global Genome and Transcriptome Analyses of Magnaporthe oryzae Epidemic Isolate 98-06 Uncover Novel Effectors and Pathogenicity-Related Genes, Revealing Gene Gain and Lose Dynamics in Genome Evolution

(2015) Yanhan Dong et al.   PLoS Pathogens

The Crystal Structure of the Adenylation Enzyme VinN Reveals a Unique β-Amino Acid Recognition Mechanism

(2014) Akimasa Miyanaga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of new enzymes and metabolic pathways by using structure and genome context

(2013) Suwen Zhao et al.   NATURE

The Cation−π Interaction

(2012) Dennis A. Dougherty   ACCOUNTS OF CHEMICAL RESEARCH

Nonprocessive [2 + 2]e- off-loading reductase domains from mycobacterial nonribosomal peptide synthetases

(2012) A. Chhabra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Carboxylic acid reductase is a versatile enzyme for the conversion of fatty acids into fuels and chemical commodities

(2012) M. K. Akhtar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ralfuranone Biosynthesis in Ralstonia solanacearum Suggests Functional Divergence in the Quinone Synthetase Family of Enzymes

(2011) Barbara Wackler et al.   CHEMISTRY & BIOLOGY

Anthranilate-Activating Modules from Fungal Nonribosomal Peptide Assembly Lines

(2010) Brian D. Ames et al.   BIOCHEMISTRY