SR9009 has REV-ERB–independent effects on cell proliferation and metabolism

Small Molecule Modulators of the Circadian Molecular Clock With Implications for Neuropsychiatric Diseases

(2019) Hyo Kyeong Cha et al.   Frontiers in Molecular Neuroscience

Circadian clock protein Rev-erbα regulates neuroinflammation

(2019) Percy Griffin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Angiotensin II Suppresses Rev-erbα Expression in THP-1 Macrophages via the Ang II Type 1 Receptor/Liver X Receptor α Pathway

(2018) Shipeng Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice

(2018) Benoit Pourcet et al.   GASTROENTEROLOGY

Time-Restricted Feeding Prevents Obesity and Metabolic Syndrome in Mice Lacking a Circadian Clock

(2018) Amandine Chaix et al.   Cell Metabolism

Production of certified reference materials for the sports doping control of the REV-ERB agonist SR9009

(2018) Stephen R. Davies et al.   Drug Testing and Analysis

Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence

(2018) Gabriele Sulli et al.   NATURE

A further insight into the metabolic profile of the nuclear receptor Rev‐erb agonist, SR9009

(2018) Monica Mazzarino et al.   Drug Testing and Analysis

REV-ERBα integrates colon clock with experimental colitis through regulation of NF-κB/NLRP3 axis

(2018) Shuai Wang et al.   Nature Communications

REV-ERBα Regulates TH17 Cell Development and Autoimmunity

(2018) Mohammed Amir et al.   Cell Reports

Rev-erb Agonist Inhibits Chikungunya and O’nyong’nyong Virus Replication

(2018) Jesse Hwang et al.   Open Forum Infectious Diseases

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals

(2017) Pedro M. Quirós et al.   JOURNAL OF CELL BIOLOGY

Rev-erb-α regulates atrophy-related genes to control skeletal muscle mass

(2017) Alicia Mayeuf-Louchart et al.   Scientific Reports

Rev-erb agonist improves adverse cardiac remodeling and survival in myocardial infarction through an anti-inflammatory mechanism

(2017) Endin Nokik Stujanna et al.   PLoS One

HNF6 and Rev-erbα integrate hepatic lipid metabolism by overlapping and distinct transcriptional mechanisms

(2016) Yuxiang Zhang et al.   GENES & DEVELOPMENT

Pharmacological and Genetic Modulation of REV-ERB Activity and Expression Affects Orexigenic Gene Expression

(2016) Ariadna Amador et al.   PLoS One

Circadian time signatures of fitness and disease

(2016) Joseph Bass et al.   SCIENCE

Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages

(2016) Dawn Z Eichenfield et al.   eLife

Chemical chronobiology: Toward drugs manipulating time

(2015) Thomas Wallach et al.   FEBS LETTERS

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Discrete functions of nuclear receptor Rev-erb  couple metabolism to the clock

(2015) Y. Zhang et al.   SCIENCE

Circadian Enhancers Coordinate Multiple Phases of Rhythmic Gene Transcription In Vivo

(2014) Bin Fang et al.   CELL

Derivation and characterization of mouse embryonic stem cells from permissive and nonpermissive strains

(2014) Anne Czechanski et al.   Nature Protocols

Nuclear receptor Rev-erbα: up, down, and all around

(2014) Logan J. Everett et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Circadian molecular clocks and cancer

(2013) Fergal C. Kelleher et al.   CANCER LETTERS

Circadian clocks and neurodegenerative diseases: time to aggregate?

(2013) Michael H Hastings et al.   CURRENT OPINION IN NEUROBIOLOGY

The nuclear receptor Rev-erbα controls circadian thermogenic plasticity

(2013) Zachary Gerhart-Hines et al.   NATURE

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription

(2013) Michael T. Y. Lam et al.   NATURE

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

(2013) Estelle Woldt et al.   NATURE MEDICINE

Rev-erb  and Rev-erb  coordinately protect the circadian clock and normal metabolic function

(2012) A. Bugge et al.   GENES & DEVELOPMENT

The circadian clock geneBMAL1is a novel therapeutic target for malignant pleural mesothelioma

(2012) Momen Elshazley et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

(2012) Laura A. Solt et al.   NATURE

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

(2012) Han Cho et al.   NATURE

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling

(2011) Russell A. Miller et al.   JOURNAL OF CLINICAL INVESTIGATION

The Circadian Clock Starts Ticking at a Developmentally Early Stage

(2010) Elzbieta Kowalska et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Development of the circadian oscillator during differentiation of mouse embryonic stem cells in vitro

(2010) Kazuhiro Yagita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Integration of Metabolism and Energetics

(2010) J. Bass et al.   SCIENCE

REV-ERBα Participates in Circadian SREBP Signaling and Bile Acid Homeostasis

(2009) Gwendal Le Martelot et al.   PLOS BIOLOGY

Regulation of Bile Acid Synthesis by the Nuclear Receptor Rev-erbα

(2008) Hélène Duez et al.   GASTROENTEROLOGY