Transcription factors IRF8 and PU.1 are required for follicular B cell development and BCL6-driven germinal center responses

Transcription Factor IRF8 Governs Enhancer Landscape Dynamics in Mononuclear Phagocyte Progenitors

(2018) Daisuke Kurotaki et al.   Cell Reports

BAFF and BAFF-Receptor in B Cell Selection and Survival

(2018) Cristian R. Smulski et al.   Frontiers in Immunology

PU.1 Regulates Ig Light Chain Transcription and Rearrangement in Pre-B Cells during B Cell Development

(2017) Carolina R. Batista et al.   JOURNAL OF IMMUNOLOGY

Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB

(2017) Simon N. Willis et al.   Nature Communications

Cutting Edge: Expression of IRF8 in Gastric Epithelial Cells Confers Protective Innate Immunity againstHelicobacter pyloriInfection

(2016) Ming Yan et al.   JOURNAL OF IMMUNOLOGY

CD83 Modulates B Cell Activation and Germinal Center Responses

(2016) Lena Krzyzak et al.   JOURNAL OF IMMUNOLOGY

PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia

(2016) S H M Pang et al.   LEUKEMIA

Emerging Functions of Natural IgM and Its Fc Receptor FCMR in Immune Homeostasis

(2016) Hongsheng Wang et al.   Frontiers in Immunology

IL-21–Driven Neoplasms in SJL Mice Mimic Some Key Features of Human Angioimmunoblastic T-Cell Lymphoma

(2015) Shweta Jain et al.   AMERICAN JOURNAL OF PATHOLOGY

Conditional knockdown of BCL2A1 reveals rate-limiting roles in BCR-dependent B-cell survival

(2015) M Sochalska et al.   CELL DEATH AND DIFFERENTIATION

Nomenclature of Toso, Fas Apoptosis Inhibitory Molecule 3, and IgM FcR

(2015) Hiromi Kubagawa et al.   JOURNAL OF IMMUNOLOGY

Regulation of bifurcating B cell trajectories by mutual antagonism between transcription factors IRF4 and IRF8

(2015) Heping Xu et al.   NATURE IMMUNOLOGY

The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation

(2014) Sebastian Carotta et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Reporter Mouse Reveals Lineage-Specific and Heterogeneous Expression of IRF8 during Lymphoid and Myeloid Cell Differentiation

(2014) Hongsheng Wang et al.   JOURNAL OF IMMUNOLOGY

Transcriptional Regulation of Germinal Center B and Plasma Cell Fates by Dynamical Control of IRF4

(2013) Kyoko Ochiai et al.   IMMUNITY

Roles of BCL6 in normal and transformed germinal center B cells

(2012) Katia Basso et al.   IMMUNOLOGICAL REVIEWS

Compensatory dendritic cell development mediated by BATF–IRF interactions

(2012) Roxane Tussiwand et al.   NATURE

BATF–JUN is critical for IRF4-mediated transcription in T cells

(2012) Peng Li et al.   NATURE

Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15

(2012) Aaron M Ring et al.   NATURE IMMUNOLOGY

A Genomic Regulatory Element That Directs Assembly and Function of Immune-Specific AP-1-IRF Complexes

(2012) E. Glasmacher et al.   SCIENCE

IRF8 Governs Expression of Genes Involved in Innate and Adaptive Immunity in Human and Mouse Germinal Center B Cells

(2011) Dong-Mi Shin et al.   PLoS One

IFN Regulatory Factor 8 Restricts the Size of the Marginal Zone and Follicular B Cell Pools

(2010) J. Feng et al.   JOURNAL OF IMMUNOLOGY

Regulation of Follicular B Cell Differentiation by the Related E26 Transformation-Specific Transcription Factors PU.1, Spi-B, and Spi-C

(2010) R. P. DeKoter et al.   JOURNAL OF IMMUNOLOGY

Development of immunoglobulin λ-chain–positive B cells, but not editing of immunoglobulin κ-chain, depends on NF-κB signals

(2009) Emmanuel Derudder et al.   NATURE IMMUNOLOGY

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

IRF8 regulates B-cell lineage specification, commitment, and differentiation

(2008) H. Wang et al.   BLOOD

Peripheral B cell subsets

(2008) David Allman et al.   CURRENT OPINION IN IMMUNOLOGY

IRF8 regulates myeloid and B lymphoid lineage diversification

(2008) Hongsheng Wang et al.   IMMUNOLOGIC RESEARCH

Repertoire-based selection into the marginal zone compartment during B cell development

(2008) John B. Carey et al.   JOURNAL OF EXPERIMENTAL MEDICINE