Histone deacetylase 4 promotes type I interferon signaling, restricts DNA viruses, and is degraded via vaccinia virus protein C6

PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells

(2019) Shuchi Agrawal Singh et al.   eLife

HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2

(2019) Ji Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATXN3 Positively Regulates Type I IFN Antiviral Response by Deubiquitinating and Stabilizing HDAC3

(2018) Qian Feng et al.   JOURNAL OF IMMUNOLOGY

Innate responses to gene knockouts impact overlapping gene networks and vary with respect to resistance to viral infection

(2018) Yonghong Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HDAC stimulates gene expression through BRD4 availability in response to IFN and in interferonopathies

(2018) Isabelle J. Marié et al.   JOURNAL OF EXPERIMENTAL MEDICINE

HDAC6 regulates cellular viral RNA sensing by deacetylation of RIG-I

(2016) S. J. Choi et al.   EMBO JOURNAL

HSV‐1 ICP27 targets the TBK1‐activated STING signalsome to inhibit virus‐induced type I IFN expression

(2016) Maria H Christensen et al.   EMBO JOURNAL

Rb selectively inhibits innate IFN-β production by enhancing deacetylation of IFN-β promoter through HDAC1 and HDAC8

(2016) Jun Meng et al.   JOURNAL OF AUTOIMMUNITY

Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity

(2016) Xia Li et al.   NATURE IMMUNOLOGY

Hypothalamic leptin action is mediated by histone deacetylase 5

(2016) Dhiraj G. Kabra et al.   Nature Communications

Vaccinia Virus Protein C6 Inhibits Type I IFN Signalling in the Nucleus and Binds to the Transactivation Domain of STAT2

(2016) Jennifer H. Stuart et al.   PLoS Pathogens

Inhibition of class I histone deacetylases by romidepsin potently induces Epstein-Barr virus lytic cycle and mediates enhanced cell death with ganciclovir

(2015) Kwai Fung Hui et al.   INTERNATIONAL JOURNAL OF CANCER

Analysis of the Functional Interchange between the IE1 and pp71 Proteins of Human Cytomegalovirus and ICP0 of Herpes Simplex Virus 1

(2015) Yongxu Lu et al.   JOURNAL OF VIROLOGY

Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

(2014) Katrina J. Falkenberg et al.   NATURE REVIEWS DRUG DISCOVERY

HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation

(2014) Maria Kalamvoki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity

(2013) G. L. Smith et al.   JOURNAL OF GENERAL VIROLOGY

Histone Deacetylase Classes I and II Regulate Kaposi's Sarcoma-Associated Herpesvirus Reactivation

(2013) H. J. Shin et al.   JOURNAL OF VIROLOGY

Primary Macrophages Rely on Histone Deacetylase 1 and 2 Expression To Induce Type I Interferon in Response to Gammaherpesvirus Infection

(2013) B. C. Mounce et al.   JOURNAL OF VIROLOGY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Endocytic tubules regulated by Rab GTPases 5 and 11 are used for envelopment of herpes simplex virus

(2012) Michael Hollinshead et al.   EMBO JOURNAL

Histone Deacetylase (HDAC) Inhibitors with a Novel Connecting Unit Linker Region Reveal a Selectivity Profile for HDAC4 and HDAC5 with Improved Activity against Chemoresistant Cancer Cells

(2012) Linda Marek et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Replication Defect of ICP0-Null Mutant Herpes Simplex Virus 1 Can Be Largely Complemented by the Combined Activities of Human Cytomegalovirus Proteins IE1 and pp71

(2012) R. D. Everett et al.   JOURNAL OF VIROLOGY

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

(2012) N. M. Archin et al.   NATURE

Recruitment of Histone Deacetylase 3 to the Interferon-A Gene Promoters Attenuates Interferon Expression

(2012) Pierre Génin et al.   PLoS One

Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages

(2012) X. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone deacetylase inhibitors are potent inducers of gene expression in latent EBV and sensitize lymphoma cells to nucleoside antiviral agents

(2011) S. K. Ghosh et al.   BLOOD

PKC alpha regulates Sendai virus-mediated interferon induction through HDAC6 and β-catenin

(2011) Jianzhong Zhu et al.   EMBO JOURNAL

Vaccinia Virus Protein C6 Is a Virulence Factor that Binds TBK-1 Adaptor Proteins and Inhibits Activation of IRF3 and IRF7

(2011) Leonie Unterholzner et al.   PLoS Pathogens

Trichostatin A blocks type I interferon production by activated plasmacytoid dendritic cells

(2010) Valentina Salvi et al.   IMMUNOBIOLOGY

Regulation of ICP0-Null Mutant Herpes Simplex Virus Type 1 Infection by ND10 Components ATRX and hDaxx

(2010) V. Lukashchuk et al.   JOURNAL OF VIROLOGY

Epigenetic regulation of CD8+ T-lymphocyte mediated suppression of HIV-1 replication

(2010) Kevin O. Saunders et al.   VIROLOGY

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

(2008) Michael Haberland et al.   NATURE REVIEWS GENETICS

Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling

(2008) Karen E. Johnson et al.   VIROLOGY