Aralia taibaiensis Protects against I/R-Induced Brain Cell Injury through the Akt/SIRT1/FOXO3a Pathway

Suppression of endothelial PGC-1α is associated with hypoxia-induced endothelial dysfunction and provides a new therapeutic target in pulmonary arterial hypertension

(2016) Jia-Xin Ye et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Aralia taibaiensis Protects Cardiac Myocytes against High Glucose-Induced Oxidative Stress and Apoptosis

(2015) Jialin Duan et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

The Protective Effect of FGF21 on Diabetes-Induced Male Germ Cell Apoptosis Is Associated With Up-Regulated Testicular AKT and AMPK/Sirt1/PGC-1α Signaling

(2015) Xin Jiang et al.   ENDOCRINOLOGY

Chikusetsu Saponin IVa Ameliorates Cerebral Ischemia Reperfusion Injury in Diabetic Mice via Adiponectin-Mediated AMPK/GSK-3β Pathway In Vivo and In Vitro

(2015) Jialin Duan et al.   MOLECULAR NEUROBIOLOGY

Chikusetsu saponin IVa confers cardioprotection via SIRT1/ERK1/2 and Homer1a pathway

(2015) Jialin Duan et al.   Scientific Reports

Colistin-induced apoptosis in PC12 cells: Involvement of the mitochondrial apoptotic and death receptor pathways

(2014) HONG JIANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Signaling pathways leading to ischemic mitochondrial neuroprotection

(2014) John W. Thompson et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Antihyperglycemic, hypolipidemic and antioxidant activities of total saponins extracted from Aralia taibaiensis in experimental type 2 diabetic rats

(2014) Yan Weng et al.   JOURNAL OF ETHNOPHARMACOLOGY

Saponins fromAralia taibaiensisAttenuate D-Galactose-Induced Aging in Rats by Activating FOXO3a and Nrf2 Pathways

(2014) Ying-Na Li et al.   Oxidative Medicine and Cellular Longevity

Reactive oxygen species regulation and antioxidant defence in halophytes

(2013) Rengin Ozgur et al.   FUNCTIONAL PLANT BIOLOGY

Ursolic acid promotes the neuroprotection by activating Nrf2 pathway after cerebral ischemia in mice

(2012) Litao Li et al.   BRAIN RESEARCH

Insulin-secretagogue activity of eleven plant extracts and twelve pure compounds isolated from Aralia taibaiensis

(2012) Jia Cui et al.   LIFE SCIENCES

Anticoagulant therapy for patients with ischaemic stroke

(2012) Graeme J. Hankey   Nature Reviews Neurology

Akt, FoxO and regulation of apoptosis

(2011) Xinbo Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

New antioxidant and antiglycation active triterpenoid saponins from the root bark of Aralia taibaiensis

(2011) Linlin Bi et al.   FITOTERAPIA

RACK1 Regulates VEGF/Flt1-mediated Cell Migration via Activation of a PI3K/Akt Pathway

(2011) Feng Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A pathway from JNK through decreased ERK and Akt activities for FOXO3a nuclear translocation in response to UV irradiation

(2011) Xianwang Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

New insights into the role of mitochondrial dysfunction and protein aggregation in Parkinson's disease

(2010) Weilin Xie et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

(2009) Carles Cantó et al.   CURRENT OPINION IN LIPIDOLOGY

Caloric restriction, SIRT1 and longevity

(2009) Carles Cantó et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Antioxidants and Free Radical Scavengers for the Treatment Of Stroke, Traumatic Brain Injury and Aging

(2008) J. Weber et al.   CURRENT MEDICINAL CHEMISTRY

Akt/FOXO3a/SIRT1-Mediated Cardioprotection byn-Tyrosol against Ischemic Stress in Rat in Vivo Model of Myocardial Infarction: Switching Gears toward Survival and Longevity

(2008) Samson Mathews Samuel et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function

(2008) Richard C. Scarpulla   PHYSIOLOGICAL REVIEWS

Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic

(2008) Manuel Yepes et al.   TRENDS IN NEUROSCIENCES

Traditional Chinese Medicine in Treatment of Metabolic Syndrome

(2008) Jun Yin et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Antioxidant and antiglycation properties of total saponins extracted from traditional Chinese medicine used to treat diabetes mellitus

(2007) Miaomiao Xi et al.   PHYTOTHERAPY RESEARCH