Saponins fromAralia taibaiensisAttenuate D-Galactose-Induced Aging in Rats by Activating FOXO3a and Nrf2 Pathways

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Chronic testosterone propionate supplement could activated the Nrf2-ARE pathway in the brain and ameliorated the behaviors of aged rats

(2013) Guo-liang Zhang et al.   BEHAVIOURAL BRAIN RESEARCH

Nutritional strategies to modulate inflammation and oxidative stress pathways via activation of the master antioxidant switch Nrf2

(2013) Ludmila F.M.F. Cardozo et al.   BIOCHIMIE

Glutathione metabolism and Parkinson's disease

(2013) Michelle Smeyne et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive oxygen species and the free radical theory of aging

(2013) Stefan I. Liochev   FREE RADICAL BIOLOGY AND MEDICINE

Therapeutic Roles of Heme Oxygenase-1 in Metabolic Diseases: Curcumin and Resveratrol Analogues as Possible Inducers of Heme Oxygenase-1

(2013) Yong Son et al.   Oxidative Medicine and Cellular Longevity

Effects of Caloric Restriction on Cardiac Oxidative Stress and Mitochondrial Bioenergetics: Potential Role of Cardiac Sirtuins

(2013) Ken Shinmura   Oxidative Medicine and Cellular Longevity

Eupatolide Inhibits PDGF-induced Proliferation and Migration of Aortic Smooth Muscle Cells Through ROS-dependent Heme Oxygenase-1 Induction

(2013) Namho Kim et al.   PHYTOTHERAPY RESEARCH

Glutathione and glutathione analogues; Therapeutic potentials

(2012) Jian Hui Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Glutathione synthesis

(2012) Shelly C. Lu   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes

(2012) Marcel Deponte   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Heme Oxygenase-1 in Tumor Biology and Therapy

(2012) Halina Was et al.   CURRENT DRUG TARGETS

Piperine and curcumin exhibit synergism in attenuating d-galactose induced senescence in rats

(2012) David Banji et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Crosstalk between Nrf2 and the proteasome: Therapeutic potential of Nrf2 inducers in vascular disease and aging

(2012) Sarah J. Chapple et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

Allicin ameliorates cognitive deficits ageing-induced learning and memory deficits through enhancing of Nrf2 antioxidant signaling pathways

(2012) Xian-Hui Li et al.   NEUROSCIENCE LETTERS

Attenuation of age-related changes in FOXO3a activity and the PI3K/Akt pathway by short-term feeding of ferulate

(2011) Yeon Ja Choi et al.   AGE

Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity in Germans

(2011) Rabea Kleindorp et al.   AGING CELL

Age-related changes of Nrf2 and phosphorylated GSK-3β in a mouse model of accelerated aging (SAMP8)

(2011) Koji Tomobe et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

FoxO transcription factors; Regulation by AKT and 14-3-3 proteins

(2011) Guri Tzivion et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Comparison of oxidative stress biomarkers in renal tissues of d-galactose induced, naturally aged and young rats

(2011) Seval Aydın et al.   BIOGERONTOLOGY

Haem oxygenase-1: non-canonical roles in physiology and pathology

(2011) Anna Grochot-Przeczek et al.   CLINICAL SCIENCE

New antioxidant and antiglycation active triterpenoid saponins from the root bark of Aralia taibaiensis

(2011) Linlin Bi et al.   FITOTERAPIA

Reactive oxygen species and PI3K/Akt signaling play key roles in the induction of Nrf2-driven heme oxygenase-1 expression in sulforaphane-treated human mesothelioma MSTO-211H cells

(2011) Yoon-Jin Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

The redox stress hypothesis of aging

(2011) Rajindar S. Sohal et al.   FREE RADICAL BIOLOGY AND MEDICINE

Increased expression of miR-34a and miR-93 in rat liver during aging, and their impact on the expression of Mgst1 and Sirt1

(2011) Na Li et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation

(2011) Brooks M. Hybertson et al.   MOLECULAR ASPECTS OF MEDICINE

D-Galactose Effectiveness in Modeling Aging and Therapeutic Antioxidant Treatment in Mice

(2011) Kodeeswaran Parameshwaran et al.   REJUVENATION RESEARCH

Mechanisms of Cell Protection by Heme Oxygenase-1

(2010) Raffaella Gozzelino et al.   Annual Review of Pharmacology and Toxicology

Forkhead Homeobox Type O Transcription Factors in the Responses to Oxidative Stress

(2010) Peter Storz   ANTIOXIDANTS & REDOX SIGNALING

Forkhead Box O as a Sensor, Mediator, and Regulator of Redox Signaling

(2010) Peter L.J. de Keizer et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial longevity pathways

(2010) Anna Raffaello et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Age-related changes in the central auditory system: Comparison of d-galactose-induced aging rats and naturally aging rats

(2010) Bei Chen et al.   BRAIN RESEARCH

Redox imbalance influence in the myocardial Akt activation in aged rats treated with DHEA

(2010) Maria Helena Vianna Metello Jacob et al.   EXPERIMENTAL GERONTOLOGY

Inhibiting NF-κB activation and ROS production are involved in the mechanism of silibinin's protection against D-galactose-induced senescence

(2010) Qiong Wang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Antioxidant and antiglycation properties of triterpenoid saponins fromAralia taibaiensistraditionally used for treating diabetes mellitus

(2010) Miaomiao Xi et al.   REDOX REPORT

Sulfasalazine induces haem oxygenase-1 via ROS-dependent Nrf2 signalling, leading to control of neointimal hyperplasia

(2009) Ju-Young Kim et al.   CARDIOVASCULAR RESEARCH

Effects of age and jet lag on d-galactose induced aging process

(2008) Yang Xu et al.   BIOGERONTOLOGY

FoxO transcription factors in the maintenance of cellular homeostasis during aging

(2008) Dervis AM Salih et al.   CURRENT OPINION IN CELL BIOLOGY

Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress

(2008) C.J. Harvey et al.   FREE RADICAL BIOLOGY AND MEDICINE

Foxo3a Inhibits Cardiomyocyte Hypertrophy through Transactivating Catalase

(2008) Wei-Qi Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protection of multiple antioxidants Chinese herbal medicine on the oxidative stress induced by adriamycin chemotherapy

(2007) Xu-Jun Qin et al.   JOURNAL OF APPLIED TOXICOLOGY

Antioxidant and antiglycation properties of total saponins extracted from traditional Chinese medicine used to treat diabetes mellitus

(2007) Miaomiao Xi et al.   PHYTOTHERAPY RESEARCH