Cancer stem cell self-renewal as a therapeutic target in human oral cancer

Subpopulations of cancer stem cells found in papillary thyroid carcinoma

(2018) Saied Mirshahidi et al.   EXPERIMENTAL CELL RESEARCH

Inhibition of BMI1 induces autophagy-mediated necroptosis

(2016) Anindya Dey et al.   Autophagy

BMI-1 Targeting Interferes with Patient-Derived Tumor-Initiating Cell Survival and Tumor Growth in Prostate Cancer

(2016) N. Bansal et al.   CLINICAL CANCER RESEARCH

Therapeutic Implications of Cellular Heterogeneity and Plasticity in Breast Cancer

(2015) Michael D. Brooks et al.   Cell Stem Cell

A differential role for CXCR4 in the regulation of normal versus malignant breast stem cell activity

(2015) Matthew P Ablett et al.   Oncotarget

Cisplatin Induces Bmi-1 and Enhances the Stem Cell Fraction in Head and Neck Cancer

(2015) Carolina Nör et al.   NEOPLASIA

Evolution of the Cancer Stem Cell Model

(2014) Antonija Kreso et al.   Cell Stem Cell

Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD

(2014) Kenji Mizumura et al.   JOURNAL OF CLINICAL INVESTIGATION

RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity

(2014) Pratyusha Mandal et al.   MOLECULAR CELL

c-Met pathway promotes self-renewal and tumorigenecity of head and neck squamous cell carcinoma stem-like cell

(2014) Young Chang Lim et al.   ORAL ONCOLOGY

Epithelial stem cell mutations that promote squamous cell carcinoma metastasis

(2013) Ruth A. White et al.   JOURNAL OF CLINICAL INVESTIGATION

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

(2013) Zhenyu Cai et al.   NATURE CELL BIOLOGY

Self-renewal as a therapeutic target in human colorectal cancer

(2013) Antonija Kreso et al.   NATURE MEDICINE

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

(2012) Liming Sun et al.   CELL

Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment

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Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer

(2012) A. Kreso et al.   SCIENCE

Eyes Wide Open: A Critical Review of Sphere-Formation as an Assay for Stem Cells

(2011) Erika Pastrana et al.   Cell Stem Cell

A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable

(2011) Hua Tian et al.   NATURE

Endothelial Cell-Initiated Signaling Promotes the Survival and Self-Renewal of Cancer Stem Cells

(2010) S. Krishnamurthy et al.   CANCER RESEARCH

Bmi-1 Is a Crucial Regulator of Prostate Stem Cell Self-Renewal and Malignant Transformation

(2010) Rita U. Lukacs et al.   Cell Stem Cell

Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer

(2010) Martin Sauvageau et al.   Cell Stem Cell

Single-marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase

(2010) Matthew R. Clay et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition

(2010) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

Persistent Malignant Stem Cells in del(5q) Myelodysplasia in Remission

(2010) Ramin Tehranchi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Characterization of Side Populations in HNSCC: Highly Invasive, Chemoresistant and Abnormal Wnt Signaling

(2010) Jun Song et al.   PLoS One

CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

(2009) Ravindra Majeti et al.   CELL

Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells

(2009) Yohei Shimono et al.   CELL

Expression level of Bmi-1 oncoprotein is associated with progression and prognosis in colon cancer

(2009) Da-wei Li et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Polycomb group protein Bmi1 expression in colon cancers predicts the survival

(2009) Jianjun Du et al.   MEDICAL ONCOLOGY

Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy

(2008) X. Li et al.   JNCI-Journal of the National Cancer Institute

Identification of RIP1 kinase as a specific cellular target of necrostatins

(2008) Alexei Degterev et al.   Nature Chemical Biology

Bmi1 is expressed in vivo in intestinal stem cells

(2008) Eugenio Sangiorgi et al.   NATURE GENETICS

Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion

(2008) J. S. Dovey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of Disease: cancer stem cells—targeting the evil twin

(2008) Andreas Trumpp et al.   Nature clinical practice. Oncology