Epithelial stem cell mutations that promote squamous cell carcinoma metastasis

Follicular cutaneous squamous cell carcinoma: an under-recognized neoplasm arising from hair appendage structures

(2013) I. Shendrik et al.   BRITISH JOURNAL OF DERMATOLOGY

Genome-Wide miRNA Expression Profiling Identifies miR-9-3 and miR-193a as Targets for DNA Methylation in Non-Small Cell Lung Cancers

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Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway

(2012) Guanglei Zhuang et al.   EMBO JOURNAL

From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma

(2012) Vladimir Ratushny et al.   JOURNAL OF CLINICAL INVESTIGATION

LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker

(2012) Dahu Chen et al.   NATURE MEDICINE

A family business: stem cell progeny join the niche to regulate homeostasis

(2012) Ya-Chieh Hsu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Basal Cell Carcinomas Arise from Hair Follicle Stem Cells in Ptch1+/− Mice

(2011) Grace Ying Wang et al.   CANCER CELL

Cancer Stem Cells in Squamous Cell Carcinoma Switch between Two Distinct Phenotypes That Are Preferentially Migratory or Proliferative

(2011) A. Biddle et al.   CANCER RESEARCH

Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation

(2011) Karin Schlegelmilch et al.   CELL

Aberrant hypermethylation ofmiR-9genes in gastric cancer

(2011) Kuo-Wang Tsai et al.   Epigenetics

MicroRNA-9 up-regulation is involved in colorectal cancer metastasis via promoting cell motility

(2011) Liang Zhu et al.   MEDICAL ONCOLOGY

Methylation of microRNA-9 is a specific and sensitive biomarker for oral and oropharyngeal squamous cell carcinomas

(2011) Jacob Minor et al.   ORAL ONCOLOGY

Identifying the cellular origin of squamous skin tumors

(2011) G. Lapouge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-  and integrin/focal adhesion kinase (FAK) signaling

(2011) M. Schober et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defining the origins of Ras/p53-mediated squamous cell carcinoma

(2011) A. C. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

(2011) C. L. Chaffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activated Kras Alters Epidermal Homeostasis of Mouse Skin, Resulting in Redundant Skin and Defective Hair Cycling

(2010) Anandaroop Mukhopadhyay et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Basaloid squamous cell carcinoma of the skin

(2010) Alan S. Boyd et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Regulation of the transcription factor NF-kappaB1 by microRNA-9 in human gastric adenocarcinoma

(2010) Hai-Ying Wan et al.   Molecular Cancer

Hsa-miR-9 methylation status is associated with cancer development and metastatic recurrence in patients with clear cell renal cell carcinoma

(2010) M A T Hildebrandt et al.   ONCOGENE

Characterization of Side Populations in HNSCC: Highly Invasive, Chemoresistant and Abnormal Wnt Signaling

(2010) Jun Song et al.   PLoS One

Rap1 Stabilizes  -Catenin and Enhances  -Catenin-Dependent Transcription and Invasion in Squamous Cell Carcinoma of the Head and Neck

(2009) M. Goto et al.   CLINICAL CANCER RESEARCH

MicroRNA-9 inhibits ovarian cancer cell growth through regulation of NF-κB1

(2009) Li-Min Guo et al.   FEBS Journal

Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation

(2009) Sophia Bornstein et al.   JOURNAL OF CLINICAL INVESTIGATION

Epidermal homeostasis: a balancing act of stem cells in the skin

(2009) Cédric Blanpain et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression

(2008) Kristina E. Hoot et al.   JOURNAL OF CLINICAL INVESTIGATION

Efficient tumour formation by single human melanoma cells

(2008) Elsa Quintana et al.   NATURE

Isolation and short-term culture of primary keratinocytes, hair follicle populations and dermal cells from newborn mice and keratinocytes from adult mice for in vitro analysis and for grafting to immunodeficient mice

(2008) Ulrike Lichti et al.   Nature Protocols