MYB regulates the DNA damage response and components of the homology-directed repair pathway in human estrogen receptor-positive breast cancer cells

Targeting the transcription factor Myb by small-molecule inhibitors

(2017) Sagar Uttarkar et al.   EXPERIMENTAL HEMATOLOGY

TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity

(2016) Pavel Moudry et al.   JOURNAL OF CELL BIOLOGY

An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma

(2016) Yotam Drier et al.   NATURE GENETICS

Functional, morphological, and apoptotic alterations in skeletal muscle of ARC deficient mice

(2015) Andrew S. Mitchell et al.   APOPTOSIS

Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction

(2015) Sagar Uttarkar et al.   BLOOD

High incidence of germlineBRCAmutation in patients with ER low-positive/PR low-positive/HER-2neunegative tumors

(2015) Rachel A. Sanford et al.   CANCER

Targeting homologous recombination, new pre-clinical and clinical therapeutic combinations inhibiting RAD51

(2015) Ambber Ward et al.   CANCER TREATMENT REVIEWS

c-MYB regulates cell growth and DNA damage repair through modulating MiR-143

(2015) Wenjun Wang et al.   FEBS LETTERS

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes

(2014) D. R. Pattabiraman et al.   BLOOD

CHIP buffers heterogeneous Bcl-2 expression levels to prevent augmentation of anticancer drug-resistant cell population

(2014) M Tsuchiya et al.   ONCOGENE

Targeting Poly(ADP-Ribose) Polymerase and the c-Myb-Regulated DNA Damage Response Pathway in Castration-Resistant Prostate Cancer

(2014) L. Li et al.   Science Signaling

Egr-1 regulates the transcription of the BRCA1 gene by etoposide

(2013) Soon Young Shin et al.   BMB Reports

DNA-Damaging Agents in Cancer Chemotherapy: Serendipity and Chemical Biology

(2013) Kahlin Cheung-Ong et al.   CHEMISTRY & BIOLOGY

NF-κB is a critical mediator of BRCA1-induced chemoresistance

(2013) M T Harte et al.   ONCOGENE

Role and potential for therapeutic targeting of MYB in leukemia

(2012) D R Pattabiraman et al.   LEUKEMIA

Homologous recombination and its regulation

(2012) L. Krejci et al.   NUCLEIC ACIDS RESEARCH

Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress

(2012) S. Liu et al.   NUCLEIC ACIDS RESEARCH

Estrogen receptor-α recruits P-TEFb to overcome transcriptional pausing in intron 1 of the MYB gene

(2012) Partha Mitra et al.   NUCLEIC ACIDS RESEARCH

Identification and Regulation of c-Myb Target Genes in MCF-7 Cells

(2011) Anita M Quintana et al.   BMC CANCER

Clinical significance of Myb protein and downstream target genes in salivary adenoid cystic carcinoma

(2011) Diana Bell et al.   CANCER BIOLOGY & THERAPY

MYB Is Essential for Mammary Tumorigenesis

(2011) R. Yu Miao et al.   CANCER RESEARCH

Residual γH2AX foci as an indication of lethal DNA lesions

(2010) Judit P Banáth et al.   BMC CANCER

Involvement of MyoD and c-myb in regulation of basal and estrogen-induced transcription activity of the BRCA1 gene

(2010) Wei Jin et al.   BREAST CANCER RESEARCH AND TREATMENT

Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination

(2010) Rémi Buisson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2

(2010) Eloïse Dray et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cellular Redistribution of Rad51 in Response to DNA Damage

(2009) Otto S. Gildemeister et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck

(2009) M. Persson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

(2009) S. M. H. Sy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA