Article
Medicine, General & Internal
Yanchun Chen, Yuan Zhang, Mengnan Zhang, Hongxi Yang, Yaogang Wang
Summary: Moderate consumption of coffee and tea is associated with lower risk of all-cause and cause-specific mortality. In addition, combining moderate consumption of both coffee and tea further reduces the risk of mortality, especially for cardiovascular and respiratory diseases.
Article
Nutrition & Dietetics
Chunyu Hu, Chunyan Huang, Jianxin Li, Fangchao Liu, Keyong Huang, Zhongying Liu, Xueli Yang, Xiaoqing Liu, Jie Cao, Shufeng Chen, Hongfan Li, Chong Shen, Ling Yu, Xigui Wu, Ying Li, Dongsheng Hu, Jianfeng Huang, Xiangfeng Lu, Dongfeng Gu
Summary: This study finds a causal relationship between alcohol consumption and cardiovascular diseases (CVDs) and all-cause mortality in Chinese males. Light and moderate drinking can reduce the risk of CVDs and all-cause mortality. However, genetically predicted alcohol consumption shows a linear association with CVDs.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Weida Qiu, Anping Cai, Liwen Li, Yingqing Feng
Summary: Long-term light and moderate alcohol consumption is associated with a lower risk of mortality and slower blood pressure increase, while heavy drinking is associated with higher blood pressure levels and mortality risk. The relationship between average alcohol intake and mortality shows a J-shaped association.
Article
Nutrition & Dietetics
Weida Qiu, Anping Cai, Xiaoju Xiao, Shuang Xia, Liwen Li, Yingqing Feng
Summary: This study aimed to investigate the relationship between tea consumption and mortality and blood pressure changes in alcohol consumers and non-consumers. The results showed that individuals with a long-term high tea consumption trajectory had a lower risk of mortality and a slower blood pressure growth rate. However, the beneficial effects of tea consumption were attenuated by alcohol intake or even harmful to health.
Article
Public, Environmental & Occupational Health
Yi Yang, Allison M. Hodge, Brigid M. Lynch, Pierre-Antoine Dugue, Elizabeth J. Williamson, Harindra Jayasekara, Gita Mishra, Dallas R. English
Summary: This study found that long-term alcohol interventions had a certain impact on all-cause mortality in women, but had little effect on cancer mortality.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Endocrinology & Metabolism
Wenbo Jiang, Qingrao Song, Jia Zhang, Yunyan Chen, Hongyan Jiang, Yujia Long, Ying Li, Tianshu Han, Hongru Sun, Wei Wei
Summary: This study investigates the association between food intake time and long-term survival among people with diabetes. The results indicate that higher intake of potato or starchy vegetable in the morning, whole grain in the afternoon, and dark vegetable and milk in the evening is associated with better long-term survival, while higher intake of processed meat in the evening is associated with higher mortality risk. Adjusted food intake timing can reduce the risk of cardiovascular disease mortality.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Nutrition & Dietetics
Shamima Akter, Tetsuya Mizoue, Akiko Nanri, Atsushi Goto, Mitsuhiko Noda, Norie Sawada, Taiki Yamaji, Motoki Iwasaki, Manami Inoue, Shoichiro Tsugane
Summary: The study found a U-shaped association between low-carbohydrate diet (LCD) score and total mortality among Asians, with high animal protein and fat in LCD associated with higher mortality risk. Conversely, a LCD high in plant-based sources of protein and fat was associated with a lower risk of total and cardiovascular mortality.
CLINICAL NUTRITION
(2021)
Article
Food Science & Technology
Hyein Jung, Sangah Shin
Summary: This study finds that higher intake of tomatoes and lycopene is inversely associated with the risk of cardiovascular disease (CVD) mortality, and lycopene consumption is associated with a lower risk of all-cause mortality.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Substance Abuse
Mindaugas Stelemekas, Jakob Manthey, Robertas Badaras, Sally Casswell, Carina Ferreira-Borges, Ramune Kalediene, Shannon Lange, Maria Neufeld, Janina Petkeviciene, Ricardas Radisauskas, Robin Room, Tadas Telksnys, Ingrida Zurlyte, Juergen Rehm
Summary: The study in Lithuania found that effective alcohol control policies were associated with a decrease in adult all-cause mortality, with measures such as increased taxation showing a significant impact. Overall, alcohol control policies appear to have contributed to reducing adult all-cause mortality rates in Lithuania.
Article
Medicine, General & Internal
Yalan Tian, Jiahui Liu, Yue Zhao, Nana Jiang, Xiao Liu, Gang Zhao, Xia Wang
Summary: This study found that moderate alcohol consumption is associated with a lower risk of mortality from various causes, including cardiovascular disease, respiratory diseases, and Alzheimer's disease. However, heavy drinking and binge drinking are associated with a higher risk of mortality.
Article
Nutrition & Dietetics
Yangbo Sun, Buyun Liu, Linda G. Snetselaar, Robert B. Wallace, Aladdin H. Shadyab, Guo-Chong Chen, James M. Shikany, JoAnn E. Manson, Wei Bao
Summary: The aim of this study was to examine the association between chocolate consumption and all-cause and cause-specific mortality. The study found a modest inverse association between moderate chocolate consumption (1-3 servings/week) and mortality from all causes, cardiovascular disease, and dementia. Chocolate consumption was not associated with cancer mortality.
JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS
(2023)
Review
Nutrition & Dietetics
Silvana Hrelia, Laura Di Renzo, Luigi Bavaresco, Elisabetta Bernardi, Marco Malaguti, Attilio Giacosa
Summary: While alcohol abuse is harmful, moderate alcohol consumption, especially of wine, is associated with health benefits. This review evaluates the relationship between the type and dose of alcoholic drink and the risk of various diseases, and emphasizes the unique benefits of moderate wine consumption, particularly in a Mediterranean diet.
Article
Psychology, Clinical
Eivind Ystrom, Eirik Degerud, Martin Tesli, Anne Hoye, Ted Reichborn-Kjennerud, Oyvind Naess
Summary: Moderate to high alcohol consumption is associated with a lower risk of cardiovascular disease mortality, but the mechanisms behind this association are still unclear. This study aimed to estimate the familial and individual risk for CVD mortality related to alcohol consumption by analyzing data from twin pairs. The results showed that familial factors accounted for the protective association of moderate to high alcohol consumption with a lower risk of CVD mortality. Early life genetic and environmental familial factors may mask any absence of health effects of moderate to high alcohol consumption on cardiovascular mortality.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Nutrition & Dietetics
Gladys Morales, Miguel A. Martinez-Gonzalez, Maria Barberia-Latasa, Maira Bes-Rastrollo, Alfredo Gea
Summary: The study aimed to assess the joint effect of adherence to the Mediterranean diet and alcohol-drinking pattern on all-cause mortality. Results indicated that individuals with low adherence to both the Mediterranean diet and alcohol-drinking pattern had higher rates of all-cause mortality compared to those with high adherence.
EUROPEAN JOURNAL OF NUTRITION
(2021)
Review
Nutrition & Dietetics
Peng-Fei Yang, Chun-Rui Wang, Fa-Bao Hao, Yang Peng, Jing-Jing Wu, Wei-Ping Sun, Jie-Jun Hu, Guo-Chao Zhong
Summary: This study aimed to determine the potential dose-response association of egg consumption with risk of mortality in the general population. Nineteen prospective cohort studies, involving 1,737,893 participants, were included. The findings showed that greater amount of egg consumption confers higher risks of death from all causes, cardiovascular disease, and cancer in a nonlinear dose-response pattern.
Article
Nutrition & Dietetics
Simona Esposito, Marialaura Bonaccio, Emilia Ruggiero, Simona Costanzo, Augusto Di Castelnuovo, Alessandro Gialluisi, Vincenzo Esposito, Gualtiero Innocenzi, Sergio Paolini, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello
Summary: This study explores the relationship between the degree of food processing and the risk of central nervous system (CNS) tumors. It is found that the intake of ultra-processed food (UPF) is associated with an increased risk of CNS tumors, especially malignant tumors, while processed food is inversely related to the risk of this disease.
CLINICAL NUTRITION
(2023)
Article
Cardiac & Cardiovascular Systems
Betul Toprak, Stephanie Brandt, Jan Brederecke, Francesco Gianfagna, Julie K. K. Vishram-Nielsen, Francisco M. Ojeda, Simona Costanzo, Christin S. Borschel, Stefan Soderberg, Ioannis Katsoularis, Stephan Camen, Erkki Vartiainen, Maria Benedetta Donati, Jukka Kontto, Martin Bobak, Ellisiv B. Mathiesen, Allan Linneberg, Wolfgang Koenig, Maja-Lisa Lochen, Augusto Di Castelnuovo, Stefan Blankenberg, Giovanni de Gaetano, Kari Kuulasmaa, Veikko Salomaa, Licia Iacoviello, Teemu Niiranen, Tanja Zeller, Renate B. Schnabel
Summary: The study aims to find reliable circulating predictors for incident atrial fibrillation (AF) using classical regressions and machine learning techniques. Fourteen routinely available biomarkers reflecting different pathophysiological pathways were examined in relation to incident AF. NT-proBNP was identified as the strongest blood-based predictor of incident AF.
Article
Medicine, General & Internal
Christin S. S. Boerschel, Bastiaan Geelhoed, Teemu Niiranen, Stephan Camen, Maria Benedetta Donati, Aki S. S. Havulinna, Francesco Gianfagna, Tarja Palosaari, Pekka Jousilahti, Jukka Kontto, Erkki Vartiainen, Francisco M. M. Ojeda, Hester M. M. den Ruijter, Simona Costanzo, Giovanni de Gaetano, Augusto Di Castelnuovo, Allan Linneberg, Julie K. K. Vishram-Nielsen, Maja-Lisa Lochen, Wolfgang Koenig, Torben Jorgensen, Kari Kuulasmaa, Stefan Blankenberg, Licia Iacoviello, Tanja Zeller, Stefan Soderberg, Veikko Salomaa, Renate B. B. Schnabel
Summary: Atrial fibrillation (AF) is on the rise and traditional cardiovascular risk factors (CVRF) cannot explain all cases. High-sensitivity troponin I (hsTnI) may help bridge this gap as a blood-based biomarker reflecting cardiac injury.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2023)
Article
Hematology
Paola Simeone, Rossella Liani, Romina Tripaldi, Sonia Ciotti, Antonio Recchiuti, Vittorio Abbonante, Benedetta Porro, Piero Del Boccio, Augusto di Castelnuovo, Paola Lanuti, Marina Camera, Damiana Pieragostino, Melissa Lee-Sundlov, Myriam Luongo, Raffaella Auciello, Giuseppina Bologna, Maria Concetta Cufaro, Elena Tremoli, Karin M. Hoffmeister, Francesco Cipollone, Alessandra Balduini, Francesca Santilli
Summary: Prevention of cardiovascular disease with low-dose aspirin may be less effective in patients with faster recovery of platelet cyclooxygenase-1 activity. Patients with accelerated COX-1 recovery exhibit reduced platelet glycoprotein Ib alpha shedding, leading to increased thrombopoietin production and the formation of platelets that are not inhibited by aspirin over 24 hours. Clinical markers including age, non-alcoholic fatty liver disease, visceral obesity, and TPO/GC ratio can accurately predict faster COX-1 recovery and suboptimal aspirin response. The TPO/GC ratio may serve as a simple tool to identify patients who would benefit from more frequent aspirin dosing.
Article
Nutrition & Dietetics
Marialaura Bonaccio, Simona Costanzo, Augusto Di Castelnuovo, Alessandro Gialluisi, Emilia Ruggiero, Amalia De Curtis, Mariarosaria Persichillo, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello
Summary: This study aimed to evaluate the association between long-term changes in adherence to a Mediterranean diet (MD) and concurrent changes in modifiable cardiovascular disease (CVD) risk factors and markers of low-grade inflammation. The results showed that increased adherence to a MD over time was associated with reduced levels of low-grade inflammation, but had little impact on CVD risk scores. These findings suggest the potential of a traditional Mediterranean eating pattern to reduce the long-term risk of inflammation-related chronic diseases in an ageing population.
JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS
(2023)
Article
Food Science & Technology
Sukshma Sharma, Augusto Di Castelnuovo, Simona Costanzo, Mariarosaria Persichillo, Teresa Panzera, Emilia Ruggiero, Amalia De Curtis, Marianna Storto, Pierpaolo Cavallo, Francesco Gianfagna, Maria Benedetta Donati, Giovanni de Gaetano, Chiara Cerletti, Licia Iacoviello, Marialaura Bonaccio, Moli Sani Study Investigators
Summary: Evidence from the Moli-sani Study suggests that adherence to a Mediterranean diet is not significantly associated with the risk of SARS-CoV-2 infection or COVID-19 diagnosis. However, higher consumption of cereals is associated with lower likelihood of SARS-CoV-2 infection, while increasing intake of olive oil, moderate alcohol consumption, and higher intake of fruits and nuts are associated with decreased likelihood of COVID-19 diagnosis. These findings emphasize the importance of adopting and maintaining a balanced Mediterranean diet to reduce the risk of future SARS-CoV-2 infections and COVID-19.
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
(2023)
Article
Endocrinology & Metabolism
Anwal Ghulam, Francesco Gianfagna, Marialaura Bonaccio, Simona Costanzo, Augusto Di Castelnuovo, Amalia De Curtis, Alessandro Gialluisi, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello
Summary: This paper aims to study the association between relative fat mass (RFM) and body mass index (BMI) with mortality in a general Italian population and potential mediators. The study found that there was an independent association between BMI > 35 kg/m(2) and RFM in the fourth quartile with mortality in men, but this association disappeared after adjusting for potential mediators. However, RFM was not predictive of mortality in women.
INTERNATIONAL JOURNAL OF OBESITY
(2023)
Article
Nutrition & Dietetics
Claudia F. Martinez, Simona Esposito, Augusto Di Castelnuovo, Simona Costanzo, Emilia Ruggiero, Amalia De Curtis, Mariarosaria Persichillo, James R. Hebert, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello, Alessandro Gialluisi, Marialaura Bonaccio
Summary: Chronological age may not accurately reflect health status, while biological age has been proposed as a relevant indicator of healthy aging. Observational studies have found that decelerated biological aging is associated with a lower risk of disease and mortality. A cross-sectional analysis was performed using data from the Moli-sani Study in Italy, and it was found that a pro-inflammatory diet is associated with accelerated biological aging and an increased risk of inflammation-related diseases and mortality.
Article
Nutrition & Dietetics
Marialaura Bonaccio, Emilia Ruggiero, Augusto Di Castelnuovo, Claudia Francisca Martinez, Simona Esposito, Simona Costanzo, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello
Summary: Late eating is associated with poor metabolic health, potentially due to low diet quality. This study found that meal timing may also be related to food processing, which affects health outcomes. Late eaters consumed less minimally processed food, more ultra-processed food, and had lower adherence to the Mediterranean Diet compared to early eaters. Future research should investigate whether increased consumption of ultra-processed food underlies the association between late eating and adverse metabolic health.
Article
Cardiac & Cardiovascular Systems
Paul M. Haller, Alina Gossling, Christina Magnussen, Hermann Brenner, Ben Schoettker, Licia Iacoviello, Simona Costanzo, Frank Kee, Wolfgang Koenig, Allan Linneberg, Chaterina Sujana, Barbara Thorand, Veikko Salomaa, Teemu J. Niiranen, Stefan Soederberg, Henry Voelzke, Marcus Doerr, Susana Sans, Teresa Padro, Stephan B. Felix, Matthias Nauck, Astrid Petersmann, Luigi Palmieri, Chiara Donfrancesco, Roberto De Ponti, Giovanni Veronesi, Marco M. Ferrario, Kari Kuulasmaa, Tanja Zeller, Francisco M. Ojeda, Stefan Blankenberg, Dirk Westermann
Summary: This study demonstrates the role of cardiac biomarkers in predicting cardiovascular events and death in both general population and individuals with known diabetes. The findings suggest that these biomarkers can help identify individuals at highest risk for cardiovascular events and improve early identification of high-risk individuals. Therefore, they should be considered for routine risk assessment and can enhance the initiation of preventive therapies.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Sucharitha Chadalavada, Jaakko Reinikainen, Jonas Andersson, Augusto Di Castelnuovo, Licia Iacoviello, Pekka Jousilahti, Line Lund Karhus, Allan Linneberg, Stefan Soderberg, Hugh Tunstall-Pedoe, Karim Lekadir, Nay Aung, Magnus T. T. Jensen, Kari Kuulasmaa, Teemu J. J. Niiranen, Steffen E. E. Petersen
Summary: This study confirms that women with type 1 diabetes have a higher risk of heart failure compared to men, but there is no significant difference in risk according to sex for type 2 diabetes patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Engineering, Manufacturing
Sunil Sharma, Prabir Sarkar
Summary: This paper addresses the challenges of capturing and representing biological knowledge in bioinspired design. The authors propose two approaches using the Zachman Framework: one for representing knowledge transfer in a bioinspired design organization, and the other to represent biological entities. The contribution of this paper is to provide a mechanism for holistic bioinspired knowledge activities and guide designers in decision-making for bioinspired design.
INTERNATIONAL JOURNAL OF INTERACTIVE DESIGN AND MANUFACTURING - IJIDEM
(2023)
Meeting Abstract
Hematology
Romy de Laat, Augusto Di Castelnuovo, Lisa van der Vorm, Simona Costanzo, Marisa Ninivaggi, Chiara Cerletti, Dana Huskens, Amalia De Curtis, Alessandro Gialluisi, Cuicui Bai, Giovanni de Gaetano, Dongmei Yin, Maria Benedatta Donati, Bas de Laat, Licia Iacoviello
INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY
(2023)
