Zfp217 mediates m6A mRNA methylation to orchestrate transcriptional and post-transcriptional regulation to promote adipogenic differentiation

Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally

(2019) Huilin Huang et al.   NATURE

R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m 6 A/MYC/CEBPA Signaling

(2018) Rui Su et al.   CELL

Maternal obesity aggravates the abnormality of porcine placenta by increasing N6-methyladenosine

(2018) Tongxing Song et al.   INTERNATIONAL JOURNAL OF OBESITY

Epigallocatechin gallate targets FTO and inhibits adipogenesis in an mRNA m6A-YTHDF2-dependent manner

(2018) Ruifan Wu et al.   INTERNATIONAL JOURNAL OF OBESITY

Balance between senescence and apoptosis is regulated by telomere damage–induced association between p16 and caspase-3

(2018) Shanmugam Panneer Selvam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis

(2018) Masatoshi Kobayashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Zinc finger proteins orchestrate active gene silencing during embryonic stem cell differentiation

(2018) Sojung Kwak et al.   NUCLEIC ACIDS RESEARCH

Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm

(2018) Jiangbo Wei et al.   MOLECULAR CELL

Critical Enzymatic Functions of FTO in Obesity and Cancer

(2018) Xiaolan Deng et al.   Frontiers in Endocrinology

The Emerging Role of Zfp217 in Adipogenesis

(2017) Hong Xiang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The structure, kinetics and interactions of the  -carboxysomal  -carbonic anhydrase, CcaA

(2016) L. D. McGurn et al.   BIOCHEMICAL JOURNAL

GPR120 promotes adipogenesis through intracellular calcium and extracellular signal-regulated kinase 1/2 signal pathway

(2016) Tongxing Song et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Post-transcriptional gene regulation by mRNA modifications

(2016) Boxuan Simen Zhao et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA

(2016) Chuanzhao Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ZNF217/ZFP217 Meets Chromatin and RNA

(2016) Dung-Fang Lee et al.   TRENDS IN BIOCHEMICAL SCIENCES

mRNA m6A methylation downregulates adipogenesis in porcine adipocytes

(2015) Xinxia Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Coordination of m 6 A mRNA Methylation and Gene Transcription by ZFP217 Regulates Pluripotency and Reprogramming

(2015) Francesca Aguilo et al.   Cell Stem Cell

Dynamic m6A mRNA methylation directs translational control of heat shock response

(2015) Jun Zhou et al.   NATURE

m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

(2015) Shay Geula et al.   SCIENCE

FTO influences adipogenesis by regulating mitotic clonal expansion

(2015) Myrte Merkestein et al.   Nature Communications

What We Talk About When We Talk About Fat

(2014) Evan D. Rosen et al.   CELL

FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis

(2014) Xu Zhao et al.   CELL RESEARCH

The dynamic epitranscriptome: N6-methyladenosine and gene expression control

(2014) Kate D. Meyer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Snail1-dependent control of embryonic stem cell pluripotency and lineage commitment

(2014) Yongshun Lin et al.   Nature Communications

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

Transcriptome-wide mapping of N6-methyladenosine by m6A-seq based on immunocapturing and massively parallel sequencing

(2013) Dan Dominissini et al.   Nature Protocols

The bigger picture of FTO—the first GWAS-identified obesity gene

(2013) Ruth J. F. Loos et al.   Nature Reviews Endocrinology

Transcriptome Comparison between Porcine Subcutaneous and Intramuscular Stromal Vascular Cells during Adipogenic Differentiation

(2013) Shuzhong Jiang et al.   PLoS One

Prognostic and therapeutic impact of the chromosome 20q13.2 ZNF217 locus amplification in ovarian clear cell carcinoma

(2011) Mohammed Tanjimur Rahman et al.   CANCER

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Transcriptional networks and chromatin remodeling controlling adipogenesis

(2011) Rasmus Siersbæk et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Lack of SIRT1 (Mammalian Sirtuin 1) Activity Leads to Liver Steatosis in the SIRT1+/−Mice: A Role of Lipid Mobilization and Inflammation

(2010) Fen Xu et al.   ENDOCRINOLOGY

The ZNF217 oncogene is a candidate organizer of repressive histone modifiers

(2010) Michaela S. Banck et al.   Epigenetics