The Novel C5aR Antagonist DF3016A Protects Neurons Against Ischemic Neuroinflammatory Injury

Epithelial C5aR1 Signaling Enhances Uropathogenic Escherichia coli Adhesion to Human Renal Tubular Epithelial Cells

(2018) Yun Song et al.   Frontiers in Immunology

Primary Cultures from Rat Dorsal Root Ganglia: Responses of Neurons and Glial Cells to Somatosensory or Inflammatory Stimulation

(2018) Stephan Leisengang et al.   NEUROSCIENCE

Degenerative Joint Diseases and Neuroinflammation

(2017) Mariella Fusco et al.   Pain Practice

Depression and chronic pain in the elderly: links and management challenges

(2017) Panagiotis Zis et al.   Clinical Interventions in Aging

MicroRNA-181 promotes synaptogenesis and attenuates axonal outgrowth in cortical neurons

(2016) Aron Kos et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The complement factor 5a receptor 1 has a pathogenic role in chronic inflammation and renal fibrosis in a murine model of chronic pyelonephritis

(2016) Naheed Choudhry et al.   KIDNEY INTERNATIONAL

C5a and pain development: An old molecule, a new target

(2016) Andreza U. Quadros et al.   PHARMACOLOGICAL RESEARCH

Establishment of Lipofection Protocol for Efficient miR-21 Transfection into Cortical NeuronsIn Vitro

(2015) Zhaoli Han et al.   DNA AND CELL BIOLOGY

Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement

(2015) Ali Alawieh et al.   Journal of Neuroinflammation

Neuromodulatory properties of inflammatory cytokines and their impact on neuronal excitability

(2015) Annamaria Vezzani et al.   NEUROPHARMACOLOGY

Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief

(2014) Alessio Moriconi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic Pain and Neurodegenerative Processes in Elderly People

(2014) Giustino Varrassi et al.   Pain Practice

Evidence for miR-181 involvement in neuroinflammatory responses of astrocytes

(2013) Emmette R. Hutchison et al.   GLIA

The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation

(2013) K. Triantafilou et al.   JOURNAL OF CELL SCIENCE

MicroRNAs Regulate the Chaperone Network in Cerebral Ischemia

(2013) Yi-Bing Ouyang et al.   Translational Stroke Research

miR-181a and inflammation: miRNA homeostasis response to inflammatory stimuli in vivo

(2012) Weidong Xie et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Generation of complement component C5a by ischemic neurons promotes neuronal apoptosis

(2012) Dale Pavlovski et al.   FASEB JOURNAL

Complement gene expression is regulated by pro-inflammatory cytokines and the anaphylatoxin C3a in human tenocytes

(2012) Catharina Busch et al.   MOLECULAR IMMUNOLOGY

Reducing safety-related drug attrition: the use of in vitro pharmacological profiling

(2012) Joanne Bowes et al.   NATURE REVIEWS DRUG DISCOVERY

Estrogen receptor alpha and beta differentially mediate C5aR agonist evoked Ca2+-influx in neurons through L-type voltage-gated Ca2+ channels

(2012) Imre Farkas et al.   NEUROCHEMISTRY INTERNATIONAL

miR-181 regulates GRP78 and influences outcome from cerebral ischemia in vitro and in vivo

(2011) Yi-Bing Ouyang et al.   NEUROBIOLOGY OF DISEASE

Complement in neuroprotection and neurodegeneration

(2010) Vijay Yanamadala et al.   TRENDS IN MOLECULAR MEDICINE

Transient Focal Ischemia Induces Extensive Temporal Changes in Rat Cerebral MicroRNAome

(2009) Ashuthosh Dharap et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Role of the Complement System and the Activation Fragment C5a in the Central Nervous System

(2009) Trent M. Woodruff et al.   NEUROMOLECULAR MEDICINE

The complement cascade: Yin-Yang in neuroinflammation - neuro-protection and -degeneration

(2008) Jessy John Alexander et al.   JOURNAL OF NEUROCHEMISTRY

Estrogen enhances expression of the complement C5a receptor and the C5a-agonist evoked calcium influx in hormone secreting neurons of the hypothalamus

(2007) Imre Farkas et al.   NEUROCHEMISTRY INTERNATIONAL