Diverse Structural Features of Potassium Channels Characterized by Scorpion Toxins as Molecular Probes

KV1.2 channel-specific blocker from Mesobuthus eupeus scorpion venom: structural basis of selectivity

(2018) Alexey I. Kuzmenkov et al.   NEUROPHARMACOLOGY

Treating autoimmune disorders with venom-derived peptides

(2017) Bingzheng Shen et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Kalium: a database of potassium channel toxins from scorpion venom

(2016) Alexey I. Kuzmenkov et al.   Database-The Journal of Biological Databases and Curation

Mesomartoxin, a new Kv1.2-selective scorpion toxin interacting with the channel selectivity filter

(2015) Xueli Wang et al.   BIOCHEMICAL PHARMACOLOGY

Computational Studies of Venom Peptides Targeting Potassium Channels

(2015) Rong Chen et al.   Toxins

Toxin acidic residue evolutionary function-guided design of de novo peptide drugs for the immunotherapeutic target, the Kv1.3 channel

(2015) Zongyun Chen et al.   Scientific Reports

Proteomic analysis of the venom from the scorpion Mesobuthus martensii

(2014) Xiaobo Xu et al.   Journal of Proteomics

Open conformation of hERG channel turrets revealed by a specific scorpion toxin BmKKx2

(2014) You-Tian Hu et al.   Cell and Bioscience

Binding Modes of Two Scorpion Toxins to the Voltage-Gated Potassium Channel Kv1.3 Revealed from Molecular Dynamics

(2014) Rong Chen et al.   Toxins

Molecular Dynamics Simulations of Scorpion Toxin Recognition by the Ca2+-Activated Potassium Channel KCa3.1

(2013) Rong Chen et al.   BIOPHYSICAL JOURNAL

Two Conserved Arginine Residues from the SK3 Potassium Channel Outer Vestibule Control Selectivity of Recognition by Scorpion Toxins

(2013) Jing Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular diversity of Chaerilidae venom peptides reveals the dynamic evolution of scorpion venom components from Buthidae to non-Buthidae

(2013) Yawen He et al.   Journal of Proteomics

Computational Methods of Studying the Binding of Toxins From Venomous Animals to Biological Ion Channels: Theory and Applications

(2013) Dan Gordon et al.   PHYSIOLOGICAL REVIEWS

The genome of Mesobuthus martensii reveals a unique adaptation model of arthropods

(2013) Zhijian Cao et al.   Nature Communications

Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K+ channel

(2013) Anirban Banerjee et al.   eLife

Hg1, Novel Peptide Inhibitor Specific for Kv1.3 Channels from First Scorpion Kunitz-type Potassium Channel Toxin Family

(2012) Zong-Yun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of the Selective Block of Kv1.2 by Maurotoxin from Computer Simulations

(2012) Rong Chen et al.   PLoS One

Modeling the Binding of Three Toxins to the Voltage-Gated Potassium Channel (Kv1.3)

(2011) Rong Chen et al.   BIOPHYSICAL JOURNAL

Extreme diversity of scorpion venom peptides and proteins revealed by transcriptomic analysis: Implication for proteome evolution of scorpion venom arsenal

(2011) Yibao Ma et al.   Journal of Proteomics

Differential molecular information of maurotoxin peptide recognizing IKCa and Kv1.2 channels explored by computational simulation

(2011) Hong Yi et al.   BMC STRUCTURAL BIOLOGY

Comparative venom gland transcriptome analysis of the scorpion Lychas mucronatus reveals intraspecific toxic gene diversity and new venomous components

(2010) Zhao Ruiming et al.   BMC GENOMICS

Protein−Protein Recognition Control by Modulating Electrostatic Interactions

(2010) Song Han et al.   JOURNAL OF PROTEOME RESEARCH

Molecular diversity of toxic components from the scorpion Heterometrus petersii venom revealed by proteomic and transcriptome analysis

(2010) Yibao Ma et al.   PROTEOMICS

Transcriptome analysis of the venom gland of the scorpion Scorpiops jendeki: implication for the evolution of the scorpion venom arsenal

(2009) Yibao Ma et al.   BMC GENOMICS

Molecular Information of Charybdotoxin Blockade in the Large Conductance Calcium-activated Potassium Channel

(2009) Su Qiu et al.   Journal of Chemical Information and Modeling

Structural Basis for Toxin Resistance of β4-Associated Calcium-activated Potassium (BK) Channels

(2008) Geliang Gan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of a Potent Peptide Inhibitor Designed for Kv1.3 Channel, a Therapeutic Target of Autoimmune Disease

(2008) Song Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Different Residues in Channel Turret Determining the Selectivity of ADWX-1 Inhibitor Peptide between Kv1.1 and Kv1.3 Channels

(2008) Shi-Jin Yin et al.   JOURNAL OF PROTEOME RESEARCH