Binding Modes of Two Scorpion Toxins to the Voltage-Gated Potassium Channel Kv1.3 Revealed from Molecular Dynamics

Unusual binding mode of scorpion toxin BmKTX onto potassium channels relies on its distribution of acidic residues

(2014) Zongyun Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel

(2014) Isabelle Baconguis et al.   CELL

Mechanism of μ-Conotoxin PIIIA Binding to the Voltage-Gated Na+ Channel NaV1.4

(2014) Rong Chen et al.   PLoS One

Why the Drosophila Shaker K+ Channel Is Not a Good Model for Ligand Binding to Voltage-Gated Kv1 Channels

(2013) Somayeh Mahdavi et al.   BIOCHEMISTRY

Complex Structures between the N-Type Calcium Channel (CaV2.2) and ω-Conotoxin GVIA Predicted via Molecular Dynamics

(2013) Rong Chen et al.   BIOCHEMISTRY

Molecular Dynamics Simulations of Scorpion Toxin Recognition by the Ca2+-Activated Potassium Channel KCa3.1

(2013) Rong Chen et al.   BIOPHYSICAL JOURNAL

Two Conserved Arginine Residues from the SK3 Potassium Channel Outer Vestibule Control Selectivity of Recognition by Scorpion Toxins

(2013) Jing Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Computational Studies of Marine Toxins Targeting Ion Channels

(2013) M. Rashid et al.   Marine Drugs

Computational Methods of Studying the Binding of Toxins From Venomous Animals to Biological Ion Channels: Theory and Applications

(2013) Dan Gordon et al.   PHYSIOLOGICAL REVIEWS

A Potent and Selective Peptide Blocker of the Kv1.3 Channel: Prediction from Free-Energy Simulations and Experimental Confirmation

(2013) M. Harunur Rashid et al.   PLoS One

Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K+ channel

(2013) Anirban Banerjee et al.   eLife

Binding Modes of μ-Conotoxin to the Bacterial Sodium Channel (NaVAb)

(2012) Rong Chen et al.   BIOPHYSICAL JOURNAL

Hg1, Novel Peptide Inhibitor Specific for Kv1.3 Channels from First Scorpion Kunitz-type Potassium Channel Toxin Family

(2012) Zong-Yun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Affinity and Selectivity of ShK Toxin for the Kv1 Potassium Channels from Free Energy Simulations

(2012) M. Harunur Rashid et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Structural and Functional Diversity of Acidic Scorpion Potassium Channel Toxins

(2012) Zong-Yun Chen et al.   PLoS One

Structural Basis of the Selective Block of Kv1.2 by Maurotoxin from Computer Simulations

(2012) Rong Chen et al.   PLoS One

Recombinant Expression of Margatoxin and Agitoxin-2 in Pichia pastoris: An Efficient Method for Production of KV1.3 Channel Blockers

(2012) Raveendra Anangi et al.   PLoS One

Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1

(2012) Roger J.P. Dawson et al.   Nature Communications

Modeling the Binding of Three Toxins to the Voltage-Gated Potassium Channel (Kv1.3)

(2011) Rong Chen et al.   BIOPHYSICAL JOURNAL

Charybdotoxin Unbinding from themKv1.3 Potassium Channel: A Combined Computational and Experimental Study

(2011) Morteza Khabiri et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

(2010) Jeffery B. Klauda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Protein−Protein Recognition Control by Modulating Electrostatic Interactions

(2010) Song Han et al.   JOURNAL OF PROTEOME RESEARCH

Kv1.3 potassium channels as a therapeutic target in multiple sclerosis

(2009) Srikant Rangaraju et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Structural Basis for Toxin Resistance of β4-Associated Calcium-activated Potassium (BK) Channels

(2008) Geliang Gan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of a Potent Peptide Inhibitor Designed for Kv1.3 Channel, a Therapeutic Target of Autoimmune Disease

(2008) Song Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Different Residues in Channel Turret Determining the Selectivity of ADWX-1 Inhibitor Peptide between Kv1.1 and Kv1.3 Channels

(2008) Shi-Jin Yin et al.   JOURNAL OF PROTEOME RESEARCH