Synthesis and antimycobacterial evaluation of new 5-(1-benzyl-1H-1,2,3-triazol-4-yl)-4-methyl-2-arylthiazole derivatives

Design and synthesis of novel dasatinib derivatives as inhibitors of leukemia stem cells

(2018) Hui-ying Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of 1,2,3-triazole hydrazide derivatives exhibiting anti-phytopathogenic activity

(2017) Xing Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives

(2017) Yogita K. Abhale et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Substituted N-Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery

(2017) Elisa Azzali et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of Imidazo[1,2-a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis

(2017) Subramanyam J. Tantry et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of new 2-aryl-4-((4-aryl-1H-1,2,3-triazol-1-yl)methyl)thiazole derivatives

(2017) Vikas Shinde et al.   RESEARCH ON CHEMICAL INTERMEDIATES

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

(2017) Antoine Daina et al.   Scientific Reports

Functional, thermodynamics, structural and biological studies of in silico-identified inhibitors of Mycobacterium tuberculosis enoyl-ACP(CoA) reductase enzyme

(2017) Leonardo K. B. Martinelli et al.   Scientific Reports

Design, synthesis and biological evaluation of imidazo[2,1-b]thiazole and benzo[d]imidazo[2,1-b]thiazole derivatives as Mycobacterium tuberculosis pantothenate synthetase inhibitors

(2016) Ganesh Samala et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Engineering another class of anti-tubercular lead: Hit to lead optimization of an intriguing class of gyrase ATPase inhibitors

(2016) Variam Ullas Jeankumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Repurposing of a drug scaffold: Identification of novel sila analogues of rimonabant as potent antitubercular agents

(2016) Remya Ramesh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, biological evaluation and molecular docking studies of some novel indenospiro derivatives as anticancer agents

(2016) Ajinkya A. Patravale et al.   Journal of the Taiwan Institute of Chemical Engineers

Novel thiazole–thiophene conjugates as adenosine receptor antagonists: Synthesis, biological evaluation and docking studies

(2015) Dhaivat H. Pandya et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Triazole: A Promising Antitubercular Agent

(2015) Rangappa S. Keri et al.   Chemical Biology & Drug Design

Thiazole: A promising heterocycle for the development of potent CNS active agents

(2015) Chandra Bhushan Mishra et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and in-vitro evaluation of 2-amino-4-arylthiazole as inhibitor of 3D polymerase against foot-and-mouth disease (FMD)

(2015) Kwi-wan Jeong et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological screening of 2′-aryl/benzyl-2-aryl-4-methyl-4′,5-bithiazolyls as possible anti-tubercular and antimicrobial agents

(2015) Yogita K. Abhale et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Chemical and biological metal nanoparticles as antimycobacterial agents: A comparative study

(2015) Richa Singh et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Fused Heterocycles: Synthesis and Antitubercular Activity of Novel 6-Substituted-2-(4-methyl-2-substituted phenylthiazol-5-yl)H-imidazo[1,2-a]pyridine

(2015) Yogita K. Abhale et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Discovery of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site

(2015) Tihomir Tomašič et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of pyrazolo–triazole hybrids as cytotoxic and apoptosis inducing agents

(2015) T. Srinivasa Reddy et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

1,2,3-Triazole derivatives as antitubercular agents: synthesis, biological evaluation and molecular docking study

(2015) Mubarak H. Shaikh et al.   MedChemComm

Design, synthesis and 3D-QSAR studies of new diphenylamine containing 1,2,4-triazoles as potential antitubercular agents

(2014) K. Mohan Krishna et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

iLOGP: A Simple, Robust, and Efficient Description of n-Octanol/Water Partition Coefficient for Drug Design Using the GB/SA Approach

(2014) Antoine Daina et al.   Journal of Chemical Information and Modeling

Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines

(2013) Dmitry V. Demchuk et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Recent Advances in the Synthesis of New Antimycobacterial Agents Based on the 1H-1,2,3-Triazoles

(2013) Daniel Gonzaga et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Discovery of the first inhibitors of bacterial enzyme d-aspartate ligase from Enterococcus faecium (Aslfm)

(2013) Veronika Škedelj et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Methyl-Thiazoles: A Novel Mode of Inhibition with the Potential to Develop Novel Inhibitors Targeting InhA in Mycobacterium tuberculosis

(2013) Pravin S. Shirude et al.   JOURNAL OF MEDICINAL CHEMISTRY

Regioselective synthesis of novel 3-allyl-2-(substituted imino)-4-phenyl-3H-thiazole and 2,2′-(1,3-phenylene)bis(3-substituted-2-imino-4-phenyl-3H-thiazole) derivatives as antibacterial agents

(2013) Jafar Abbasi Shiran et al.   JOURNAL OF MOLECULAR STRUCTURE

Abyssomicins from the South China Sea Deep-Sea SedimentVerrucosisporasp.: Natural Thioether Michael Addition Adducts as Antitubercular Prodrugs

(2012) Qian Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The biology and chemistry of antifungal agents: A review

(2012) Muthu K Kathiravan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Development of 5-nitrothiazole derivatives: Identification of leads against both replicative and latent Mycobacterium tuberculosis

(2012) Variam Ullas Jeankumar et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and biological evaluation of some novel thiazole substituted benzotriazole derivatives

(2012) Nitin D. Gaikwad et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and pharmacological evaluation of a novel series of 3-aryl-2-(2-substituted-4-methylthiazole-5-yl)thiazolidin-4-one as possible anti-inflammatory and antimicrobial agents

(2012) Shivaji H. Shelke et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Hybrids of ravuconazole: Synthesis and biological evaluation

(2012) Nitin D. Gaikwad et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, and Structure–Activity Correlations of Novel Dibenzo[b,d]furan, Dibenzo[b,d]thiophene, and N-Methylcarbazole Clubbed 1,2,3-Triazoles as Potent Inhibitors of Mycobacterium tuberculosis

(2012) Santhosh Reddy Patpi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Efficient synthesis and in vitro antitubercular activity of 1,2,3-triazoles as inhibitors of Mycobacterium tuberculosis

(2011) Poovan Shanmugavelan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Thiazoles: having diverse biological activities

(2011) Shiv Jee Kashyap et al.   MEDICINAL CHEMISTRY RESEARCH

N-(5-substituted thiazol-2-yl)-2-aryl-3-(tetrahydro-2H-pyran-4-yl) propanamides as glucokinase activators

(2011) Zhiqing Liu et al.   MedChemComm

Imidazo[2,1-b]thiazole carbohydrate derivatives: Synthesis and antiviral activity against Junin virus, agent of Argentine hemorrhagic fever

(2010) José Sebastián Barradas et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Thiazole and Oxazole Alkaloids: Isolation and Synthesis

(2010) Danilo Davyt et al.   Marine Drugs

NH-1,2,3-Triazole Inhibitors of the VIM-2 Metallo-β-Lactamase

(2010) Timo Weide et al.   ACS Medicinal Chemistry Letters

Extensively Drug-Resistant Tuberculosis: A New Face to an Old Pathogen

(2009) Sheela Shenoi et al.   Annual Review of Medicine

Synthesis and anticancer activity of novel 3,4-diarylthiazol-2(3H)-ones (imines)

(2009) Zong-Ying Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and antimicrobial activity evaluation of new 1,2,4-triazoles and 1,3,4-thiadiazoles bearing imidazo[2,1-b]thiazole moiety

(2009) Nuray Ulusoy Güzeldemirci et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Identification of a Metabolically Stable Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Antimalarial Activity in Mice

(2009) Ramesh Gujjar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and evaluation of analgesic, anti-inflammatory and ulcerogenic activities of some triazolo- and 2-pyrazolyl-pyrido[2,3-d]-pyrimidines

(2008) Hend Hafez et al.   ACTA PHARMACEUTICA

Design and synthesis of some thiazolyl and thiadiazolyl derivatives of antipyrine as potential non-acidic anti-inflammatory, analgesic and antimicrobial agents

(2008) Sherif A.F. Rostom et al.   BIOORGANIC & MEDICINAL CHEMISTRY

SAR study of clubbed [1,2,4]-triazolyl with fluorobenzimidazoles as antimicrobial and antituberculosis agents

(2008) Ganesh Rajaram Jadhav et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Adamantane derivatives of thiazolyl-N-substituted amide, as possible non-steroidal anti-inflammatory agents

(2008) Omar Kouatly et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and characterization of novel 2-(2,4-disubstituted-thiazole-5-yl)-3-aryl-3H-quinazoline-4-one derivatives as inhibitors of NF-κB and AP-1 mediated transcription activation and as potential anti-inflammatory agents

(2008) Rajan S. Giri et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A simple whole cell based high throughput screening protocol using Mycobacterium bovis BCG for inhibitors against dormant and active tubercle bacilli

(2008) Arshad Khan et al.   JOURNAL OF MICROBIOLOGICAL METHODS