Identification of a leukemia-initiating stem cell in human mast cell leukemia

Mastocytosis: 2016 updated WHO classification and novel emerging treatment concepts

(2016) Peter Valent et al.   BLOOD

Complete response to gemtuzumab ozogamicin in a patient with refractory mast cell leukemia

(2016) I Alvarez-Twose et al.   LEUKEMIA

Efficacy and Safety of Midostaurin in Advanced Systemic Mastocytosis

(2016) Jason Gotlib et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of the Ki-1 antigen (CD30) as a novel therapeutic target in systemic mastocytosis

(2015) Katharina Blatt et al.   BLOOD

Refined diagnostic criteria and classification of mast cell leukemia (MCL) and myelomastocytic leukemia (MML): a consensus proposal

(2014) P. Valent et al.   ANNALS OF ONCOLOGY

Dipeptidylpeptidase IV (CD26) defines leukemic stem cells (LSC) in chronic myeloid leukemia

(2014) H. Herrmann et al.   BLOOD

A new human mast cell line expressing a functional IgE receptor converts to tumorigenic growth by KIT D816V transfection

(2014) R. Saleh et al.   BLOOD

Identification of Campath-1 (CD52) as Novel Drug Target in Neoplastic Stem Cells in 5q-Patients with MDS and AML

(2014) K. Blatt et al.   CLINICAL CANCER RESEARCH

SRSF2-p95 hotspot mutation is highly associated with advanced forms of mastocytosis and mutations in epigenetic regulator genes

(2014) K. Hanssens et al.   HAEMATOLOGICA

Flow Cytometry in Mastocytosis

(2014) Laura Sánchez-Muñoz et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Hematopoietic Stem-Cell Transplantation for Advanced Systemic Mastocytosis

(2014) Celalettin Ustun et al.   JOURNAL OF CLINICAL ONCOLOGY

ASXL1 but Not TET2 Mutations Adversely Impact Overall Survival of Patients Suffering Systemic Mastocytosis with Associated Clonal Hematologic Non-Mast-Cell Diseases

(2014) Gandhi Damaj et al.   PLoS One

Comprehensive mutational profiling in advanced systemic mastocytosis

(2013) J. Schwaab et al.   BLOOD

Mast cell leukemia

(2012) S. Georgin-Lavialle et al.   BLOOD

Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation

(2012) S. Takagi et al.   BLOOD

Blood CD34-c-Kit+ cell rate correlates with aggressive forms of systemic mastocytosis and behaves like a mast cell precursor

(2011) S. Georgin-Lavialle et al.   BLOOD

A case of mast cell leukaemia with exon 9 KIT mutation and good response to imatinib

(2011) Andrzej Mital et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34- fraction

(2010) D. C. Taussig et al.   BLOOD

Targeting of Leukemia-Initiating Cells to Develop Curative Drug Therapies: Straightforward but Nontrivial Concept

(2010) P. Valent   CURRENT CANCER DRUG TARGETS

Clonal analysis of NRAS activating mutations in KIT-D816V systemic mastocytosis

(2010) T. M. Wilson et al.   HAEMATOLOGICA

Mast cells from different molecular and prognostic subtypes of systemic mastocytosis display distinct immunophenotypes

(2010) Cristina Teodosio et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Aberrant expression of CD30 in neoplastic mast cells in high-grade mastocytosis

(2010) Karl Sotlar et al.   MODERN PATHOLOGY

High frequency of concomitant mastocytosis in patients with acute myeloid leukemia exhibiting the transforming KIT mutation D816V

(2010) Robert Fritsche-Polanz et al.   Molecular Oncology

Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein

(2010) M. Jaras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Therapeutic Targets for Quiescent, Chemotherapy-Resistant Human Leukemia Stem Cells

(2010) Y. Saito et al.   Science Translational Medicine

Pathogenesis, classification and treatment of mastocytosis: state of the art in 2010 and future perspectives

(2010) Michel Arock et al.   Expert Review of Hematology

Systemic mastocytosis in 342 consecutive adults: survival studies and prognostic factors

(2009) K.-H. Lim et al.   BLOOD

Chronic myelogenous leukemia stem cells: What’s new?

(2009) Mhairi Copland   Current Hematologic Malignancy Reports

Mast cell leukemia: a report of ten cases

(2008) Caterina Giovanna Valentini et al.   ANNALS OF HEMATOLOGY

Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells

(2008) D. C. Taussig et al.   BLOOD

Regulation of Hematopoietic Stem Cells by the Steel Factor/KIT Signaling Pathway

(2008) D. Kent et al.   CLINICAL CANCER RESEARCH

Chronic Myeloid Leukemia Stem Cells

(2008) Edward Kavalerchik et al.   JOURNAL OF CLINICAL ONCOLOGY