4.1 Article

Flow Cytometry in Mastocytosis Utility as a Diagnostic and Prognostic Tool

Journal

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.iac.2014.01.008

Keywords

Mast cells; Mastocytosis; Flow cytometry; Bone marrow; Cell purification; Diagnosis; Classification; Prognosis

Funding

  1. Fondo de Investigaciones Sanitarias (FIS) of the Instituto de Salud Carlos III, Ministerio de Economia y Competitividad of Spain [PS09/00032]
  2. Fundacion Sociosanitaria de Castilla-La Mancha [2010/008]
  3. Fundacion Espanola de Mastocitosis (FEM)

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This article presents information for the identification and characterization of mast cells from bone marrow and other tissues using multiparametric flow cytometry. In addition, it provides guidelines for the application of this technique in the subclassification of systemic mastocytosis and assessment of the long-term prognosis of patients individually.

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