BRCA Mutations, DNA Repair Deficiency, and Ovarian Aging1

Increased DNA damage and repair deficiency in granulosa cells are associated with ovarian aging in rhesus monkey

(2015) Dongdong Zhang et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Changes in the expression of DNA double strand break repair genes in primordial follicles from immature and aged rats

(2015) Vijayakumar Govindaraj et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Stress and DNA repair biology of the Fanconi anemia pathway

(2014) S. Longerich et al.   BLOOD

Cancers associated withBRCA1andBRCA2mutations other than breast and ovarian

(2014) Jacqueline Mersch et al.   CANCER

Different fates of oocytes with DNA double-strand breaksin vitroandin vivo

(2014) Fei Lin et al.   CELL CYCLE

BRCA1 germline mutations may be associated with reduced ovarian reserve

(2014) Erica T. Wang et al.   FERTILITY AND STERILITY

BRCA Mutation Carriers Do Not Have Compromised Ovarian Reserve

(2014) Rachel Michaelson-Cohen et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Age-Related Decline in DNA Repair Function Explains Diminished Ovarian Reserve, Earlier Menopause, and Possible Oocyte Vulnerability to Chemotherapy in Women WithBRCAMutations

(2014) Kutluk Oktay et al.   JOURNAL OF CLINICAL ONCOLOGY

Defying DNA Double-Strand Break-Induced Death during Prophase I Meiosis by Temporal TAp63  Phosphorylation Regulation in Developing Mouse Oocytes

(2014) D.-A. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer

(2014) Johanna I. Kiiski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversal of Female Infertility by Chk2 Ablation Reveals the Oocyte DNA Damage Checkpoint Pathway

(2014) E. Bolcun-Filas et al.   SCIENCE

Hypersensitivity of Primordial Germ Cells to Compromised Replication-Associated DNA Repair Involves ATM-p53-p21 Signaling

(2014) Yunhai Luo et al.   PLoS Genetics

Comparison of age at natural menopause inBRCA1/2mutation carriers with a non-clinic-based sample of women in northern California

(2013) Wayne T. Lin et al.   CANCER

Frequency of premature menopause in women who carry a BRCA1 or BRCA2 mutation

(2013) Amy Finch et al.   FERTILITY AND STERILITY

BRCA mutations and fertility: do not push the envelope!

(2013) Nanette Santoro   FERTILITY AND STERILITY

Do BRCA1 and BRCA2 Mutation Carriers Have Earlier Natural Menopause Than Their Noncarrier Relatives? Results From the Kathleen Cuningham Foundation Consortium for Research Into Familial Breast Cancer

(2013) Ian M. Collins et al.   JOURNAL OF CLINICAL ONCOLOGY

Chemotherapy-Induced Amenorrhea in Patients With Breast Cancer With aBRCA1orBRCA2Mutation

(2013) Adriana Valentini et al.   JOURNAL OF CLINICAL ONCOLOGY

Age-associated telomere shortening in mouse oocytes

(2013) Tomoko Yamada-Fukunaga et al.   Reproductive Biology and Endocrinology

Human Ovarian Tissue Cortex Surrounding Benign and Malignant Lesions

(2013) Mary Ellen Pavone et al.   Reproductive Sciences

Shorter telomere length is associated with increased ovarian cancer risk in both familial and sporadic cases

(2012) Beatriz Martinez-Delgado et al.   JOURNAL OF MEDICAL GENETICS

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

(2012) Lisette Stolk et al.   NATURE GENETICS

Telomere Shortening Alters the Kinetics of the DNA Damage Response after Ionizing Radiation in Human Cells

(2011) R. Drissi et al.   Cancer Prevention Research

Effects of BRCA1 and BRCA2 mutations on female fertility

(2011) K. R. Smith et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Telomere DNA Deficiency Is Associated with Development of Human Embryonic Aneuploidy

(2011) Nathan R. Treff et al.   PLoS Genetics

Cell biology of cancer: BRCA1 and sister chromatid pairing reactions?

(2010) Robert V. Skibbens   CELL CYCLE

DNA double strand break repair, chromosome synapsis and transcriptional silencing in meiosis

(2010) Akiko Inagaki et al.   Epigenetics

Telomere length is associated with types of chromosome 21 nondisjunction: a new insight into the maternal age effect on Down syndrome birth

(2010) Sujoy Ghosh et al.   HUMAN GENETICS

BRCA1 knock-down causes telomere dysfunction in mammary epithelial cells

(2009) E. Cabuy et al.   CYTOGENETIC AND GENOME RESEARCH

Fertility in women with BRCA mutations: a case-control study

(2009) Tuya Pal et al.   FERTILITY AND STERILITY

Association of BRCA1 Mutations With Occult Primary Ovarian Insufficiency: A Possible Explanation for the Link Between Infertility and Breast/Ovarian Cancer Risks

(2009) Kutluk Oktay et al.   JOURNAL OF CLINICAL ONCOLOGY

Nuclear DNA Damage as a Direct Cause of Aging

(2009) Benjamin P. Best   REJUVENATION RESEARCH

BRCA1 Is Required for Meiotic Spindle Assembly and Spindle Assembly Checkpoint Activation in Mouse Oocytes1

(2008) Bo Xiong et al.   BIOLOGY OF REPRODUCTION

Telomeres and reproductive aging

(2008) David L. Keefe et al.   REPRODUCTION FERTILITY AND DEVELOPMENT