CCR5 silencing reduces inflammatory response, inhibits viability, and promotes apoptosis of synovial cells in rat models of rheumatoid arthritis through the MAPK signaling pathway

CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion

(2018) Xuanmao Jiao et al.   CANCER RESEARCH

Icariin inhibits MMP-1, MMP-3 and MMP-13 expression through MAPK pathways in IL-1β-stimulated SW1353 chondrosarcoma cells

(2017) Li Zeng et al.   Molecular Medicine Reports

MEK inhibitor, PD98059, promotes breast cancer cell migration by inducing β-catenin nuclear accumulation

(2017) Ying Zhao et al.   ONCOLOGY REPORTS

The Role of Natural Antibodies to CC Chemokine Receptor 5 in HIV Infection

(2017) Assunta Venuti et al.   Frontiers in Immunology

Cell-specific Kaiso (ZBTB33) Regulation of Cell Cycle through Cyclin D1 and Cyclin E1

(2016) Amir Pozner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway as a Discovery Target in Stroke

(2016) Jing Sun et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Blockade of the chemokine receptor, CCR5, reduces the growth of orthotopically injected colon cancer cells via limiting cancer-associated fibroblast accumulation

(2016) Yamato Tanabe et al.   Oncotarget

Critical roles of chemokine receptor CCR5 in regulating glioblastoma proliferation and invasion

(2015) Lanfu Zhao et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Is air pollution a risk factor for rheumatoid arthritis?

(2015) Mickael Essouma et al.   Journal of Inflammation-London

PBRM1 suppresses bladder cancer by cyclin B1 induced cell cycle arrest

(2015) Li Huang et al.   Oncotarget

Association of single nucleotide polymorphisms (SNPs) of PADI4 gene with rheumatoid arthritis (RA) in Indian population

(2015) Kalpana Panati et al.   GENES & GENETIC SYSTEMS

Crucial involvement of the CCL3-CCR5 axis-mediated fibroblast accumulation in colitis-associated carcinogenesis in mice

(2014) Soichiro Sasaki et al.   INTERNATIONAL JOURNAL OF CANCER

Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV

(2014) Pablo Tebas et al.   NEW ENGLAND JOURNAL OF MEDICINE

Toll-Like Receptors Expressed by Synovial Fibroblasts Perpetuate Th1 and Th17 Cell Responses in Rheumatoid Arthritis

(2014) Fanlei Hu et al.   PLoS One

Quercetin Suppresses MIP-1α–Induced Adipose Inflammation by Downregulating Its Receptors CCR1/CCR5 and Inhibiting Inflammatory Signaling

(2013) Hye-Ji Noh et al.   JOURNAL OF MEDICINAL FOOD

Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: a randomised phase 3 trial

(2013) Gerd R Burmester et al.   LANCET

The CCL5/CCR5 axis contributes to the perineural invasion of human salivary adenoid cystic carcinoma

(2013) ZHIYUAN SHEN et al.   ONCOLOGY REPORTS

CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells

(2012) M. Velasco-Velazquez et al.   CANCER RESEARCH

Long-term followup for rheumatoid arthritis patients in a multicenter outcomes study of silicone metacarpophalangeal joint arthroplasty

(2012) Kevin C. Chung et al.   ARTHRITIS CARE & RESEARCH

Variation of Matrix Metalloproteinase 1 and 3 Haplotypes and Their Serum Levels in Patients with Rheumatoid Arthritis and Osteoarthritis

(2011) Somia H. Abd-Allah et al.   Genetic Testing and Molecular Biomarkers

Pathogenetic, clinical and pharmaco-economic assessment in rheumatoid arthritis (RA)

(2011) Gianfranco Ferraccioli et al.   Internal and Emergency Medicine

The type I IFN system in rheumatoid arthritis

(2010) Paola Conigliaro et al.   AUTOIMMUNITY

TNF-α levels are not increased in inflamed patients carrying the CCR5 deletion 32

(2010) Friso L.H. Muntinghe et al.   CYTOKINE

The environment, geo-epidemiology, and autoimmune disease: Rheumatoid arthritis

(2010) Gabriel J. Tobón et al.   JOURNAL OF AUTOIMMUNITY

CC Chemokine Receptor 5 (CCR5) Desensitization

(2010) Jean-Michel Escola et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

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(2010) Juan Zhang et al.   MOLECULAR MEDICINE

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

(2010) Eli A Stahl et al.   NATURE GENETICS

Epidemiology of Rheumatoid Arthritis: Rheumatoid Arthritis and Mortality

(2010) Elena Myasoedova et al.   Current Rheumatology Reports

Role of CCR5 Δ32 bp deletion in RA and SLE

(2009) H. A. Martens et al.   AUTOIMMUNITY

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

(2009) Beatrix Bartok et al.   IMMUNOLOGICAL REVIEWS

C-C Chemokine Receptor 5 on Pulmonary Fibrocytes Facilitates Migration and Promotes Metastasis via Matrix Metalloproteinase 9

(2008) Hendrik W. van Deventer et al.   AMERICAN JOURNAL OF PATHOLOGY

MAPK phosphatases as novel targets for rheumatoid arthritis

(2008) Jennifer A Ralph et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Epigallocatechin-3-gallate suppresses TNF-α -induced production of MMP-1 and -3 in rheumatoid arthritis synovial fibroblasts

(2008) Hee-Jin Yun et al.   RHEUMATOLOGY INTERNATIONAL

Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

(2007) Melissa R. Junttila et al.   FASEB JOURNAL

Long-term exposure to medium-dose glucocorticoid therapy associates with hypertension in patients with rheumatoid arthritis

(2007) V. F. Panoulas et al.   RHEUMATOLOGY