Hypoxia-Induced Epithelial-To-Mesenchymal Transition Mediates Fibroblast Abnormalities via EKR Activation in Cutaneous Wound Healing

Recent Understandings of Biology, Prophylaxis and Treatment Strategies for Hypertrophic Scars and Keloids

(2018) Ho Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Comparative characterization of SHED and DPSCs during extended cultivation in�vitro

(2018) Huihui Wang et al.   Molecular Medicine Reports

Transcription factor GATA4 associates with mesenchymal-like gene expression in human hepatoblastoma cells

(2018) Tea Soini et al.   TUMOR BIOLOGY

High-Mobility Group Box 1 Mediates Fibroblast Activity via RAGE-MAPK and NF-κB Signaling in Keloid Scar Formation

(2017) Jihee Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Signalling pathways involved in hypoxia-induced renal fibrosis

(2017) Minna Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

TGFβ engages MEK/ERK to differentially regulate benign and malignant pancreas cell function

(2017) D R Principe et al.   ONCOGENE

Egr-1 Mediates Chronic Hypoxia-Induced Renal Interstitial Fibrosis via the PKC/ERK Pathway

(2017) Shiren Sun et al.   AMERICAN JOURNAL OF NEPHROLOGY

Site-specific gene expression profiling as a novel strategy for unravelling keloid disease pathobiology

(2017) N. Jumper et al.   PLoS One

Hypoxia-inducible factor 1α-induced epithelial–mesenchymal transition of endometrial epithelial cells may contribute to the development of endometriosis

(2016) Yao Xiong et al.   HUMAN REPRODUCTION

Sorafenib exerts an anti-keloid activity by antagonizing TGF-β/Smad and MAPK/ERK signaling pathways

(2016) Wenbo Wang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Induction of Connective Tissue Growth Factor Expression by Hypoxia in Human Lung Fibroblasts via the MEKK1/MEK1/ERK1/GLI-1/GLI-2 and AP-1 Pathways

(2016) Yi Cheng et al.   PLoS One

Phosphorylated-p38 mitogen-activated protein kinase expression is associated with clinical factors in invasive breast cancer

(2016) Bin Wang et al.   SpringerPlus

Keloid-derived keratinocytes acquire a fibroblast-like appearance and an enhanced invasive capacity in a hypoxic microenvironment in vitro

(2015) XIAOYANG MA et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Heat Shock Protein 90 Inhibitor (17-AAG) Induces Apoptosis and Decreases Cell Migration/Motility of Keloid Fibroblasts

(2015) In Sik Yun et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Endothelial-to-mesenchymal transition induced by Wnt 3a in keloid pathogenesis

(2015) Won Jai Lee et al.   WOUND REPAIR AND REGENERATION

Epithelial-mesenchymal transition in keloid tissues and TGF-β1-induced hair follicle outer root sheath keratinocytes

(2015) Li Yan et al.   WOUND REPAIR AND REGENERATION

Recruited mast cells in the tumor microenvironment enhance bladder cancer metastasis via modulation of ERβ/CCL2/CCR2 EMT/MMP9 signals

(2015) Qun Rao et al.   Oncotarget

Actin Cytoskeleton Regulation of Epithelial Mesenchymal Transition in Metastatic Cancer Cells

(2015) Jay Shankar et al.   PLoS One

Hypoxia Enhances Proliferation of Human Adipose-Derived Stem Cells via HIF-1ɑ Activation

(2015) Natsuko Kakudo et al.   PLoS One

Fn14, a Downstream Target of the TGF-β Signaling Pathway, Regulates Fibroblast Activation

(2015) Shaoxian Chen et al.   PLoS One

Hypoxia enhances proliferation and stemness of human adipose-derived mesenchymal stem cells

(2014) Caterina Fotia et al.   CYTOTECHNOLOGY

Hypoxic Conditioned Medium from Human Amniotic Fluid-Derived Mesenchymal Stem Cells Accelerates Skin Wound Healing through TGF-β/SMAD2 and PI3K/Akt Pathways

(2014) Eun Jun et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeting RAS–ERK signalling in cancer: promises and challenges

(2014) Ahmed A. Samatar et al.   NATURE REVIEWS DRUG DISCOVERY

Pathological niche environment transforms dermal stem cells to keloid stem cells: A hypothesis of keloid formation and development

(2013) Miao Qu et al.   MEDICAL HYPOTHESES

Critical Role of Transforming Growth Factor Beta in Different Phases of Wound Healing

(2013) Mohammadreza Pakyari et al.   Advances in Wound Care

Mechanosignaling pathways in cutaneous scarring

(2012) Chenyu Huang et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Enhanced expression of membrane transporter and drug resistance in keloid fibroblasts

(2012) Nan Song et al.   HUMAN PATHOLOGY

Are keloid and hypertrophic scar different forms of the same disorder? A fibroproliferative skin disorder hypothesis based on keloid findings

(2012) Chenyu Huang et al.   International Wound Journal

Hypoxia-inducible factor signaling in the development of tissue fibrosis

(2011) Debra F. Higgins et al.   CELL CYCLE

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(2011) Gerd Gauglitz et al.   MOLECULAR MEDICINE

MEK/ERK inhibitors: proof-of-concept studies in lung fibrosis

(2011) Andrew Leask   Journal of Cell Communication and Signaling

Hypoxia, Snail and incomplete epithelial–mesenchymal transition in breast cancer

(2009) K Lundgren et al.   BRITISH JOURNAL OF CANCER

ERK/MAPK activation involves hypoxia-induced MGr1-Ag/37LRP expression and contributes to apoptosis resistance in gastric cancer

(2009) Lili Liu et al.   INTERNATIONAL JOURNAL OF CANCER

Human Skin Keloid Fibroblasts Display Bioenergetics of Cancer Cells

(2007) Annette S. Vincent et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY