Differences in Liver TFAM Binding to mtDNA and mtDNA Damage between Aged and Extremely Aged Rats

Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers

(2018) Chengcheng Li et al.   EXPERIMENTAL GERONTOLOGY

Increased TFAM binding to mtDNA damage hot spots is associated with mtDNA loss in aged rat heart

(2018) Guglielmina Chimienti et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dietary supplementation with acetyl- l -carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats

(2017) Luigi Nicassio et al.   EXPERIMENTAL GERONTOLOGY

Risky repair: DNA-protein crosslinks formed by mitochondrial base excision DNA repair enzymes acting on free radical lesions

(2017) Rachel Audrey Caston et al.   FREE RADICAL BIOLOGY AND MEDICINE

Centenarians as a model to discover genetic and epigenetic signatures of healthy ageing

(2017) Annibale Alessandro Puca et al.   MECHANISMS OF AGEING AND DEVELOPMENT

“What makes some rats live so long?” The mitochondrial contribution to longevity through balance of mitochondrial dynamics and mtDNA content

(2016) Anna Picca et al.   EXPERIMENTAL GERONTOLOGY

Regulation of mitochondrial genome replication by hypoxia: The role of DNA oxidation in D-loop region

(2016) Viktor M. Pastukh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genetic factors associated with longevity: A review of recent findings

(2015) Aladdin H. Shadyab et al.   AGEING RESEARCH REVIEWS

Mitochondrial quality control pathways as determinants of metabolic health

(2015) Ntsiki M. Held et al.   BIOESSAYS

Mitochondrial responsibility in ageing process: innocent, suspect or guilty

(2015) Guillermo López-Lluch et al.   BIOGERONTOLOGY

Mitochondrial Aging and Physical Decline: Insights From Three Generations of Women

(2015) Sadie L. Hebert et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Regulation of mitochondrial biogenesis through TFAM–mitochondrial DNA interactions

(2015) Anna Picca et al.   MITOCHONDRION

A comparison among the tissue-specific effects of aging and calorie restriction on TFAM amount and TFAM-binding activity to mtDNA in rat

(2014) Anna Picca et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mitochondrial DNA copy number in peripheral blood cells declines with age and is associated with general health among elderly

(2014) Jonas Mengel-From et al.   HUMAN GENETICS

We Are Ageing

(2014) Genovefa D. Kolovou et al.   Biomed Research International

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Aging and Calorie Restriction Oppositely Affect Mitochondrial Biogenesis through TFAM Binding at Both Origins of Mitochondrial DNA Replication in Rat Liver

(2013) Anna Picca et al.   PLoS One

Age- and calorie restriction-related changes in rat brain mitochondrial DNA and TFAM binding

(2012) Anna Picca et al.   AGE

Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number

(2012) Christopher T. Campbell et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Transcription from the second heavy-strand promoter of human mtDNA is repressed by transcription factor A in vitro

(2012) M. F. Lodeiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional requirements of the distal heavy-strand promoter of mtDNA

(2012) O. Zollo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acetyl-l-Carnitine Activates the Peroxisome Proliferator-Activated Receptor-γ Coactivators PGC-1α/PGC-1β–Dependent Signaling Cascade of Mitochondrial Biogenesis and Decreases the Oxidized Peroxiredoxins Content in Old Rat Liver

(2012) Vito Pesce et al.   REJUVENATION RESEARCH

Number matters: control of mammalian mitochondrial DNA copy number

(2009) Laura L. Clay Montier et al.   Journal of Genetics and Genomics

Age-related activation of mitochondrial caspase-independent apoptotic signaling in rat gastrocnemius muscle

(2008) Emanuele Marzetti et al.   MECHANISMS OF AGEING AND DEVELOPMENT