Expression and Activity of TRPA1 and TRPV1 in the Intervertebral Disc: Association with Inflammation and Matrix Remodeling

TRPC6 in simulated microgravity of intervertebral disc cells

(2018) Alfredo Franco-Obregón et al.   EUROPEAN SPINE JOURNAL

TRPV4 inhibition attenuates stretch-induced inflammatory cellular responses and lung barrier dysfunction during mechanical ventilation

(2018) N. Pairet et al.   PLoS One

Inflammaging in cervical and lumbar degenerated intervertebral discs: analysis of proinflammatory cytokine and TRP channel expression

(2017) Aleksandra Sadowska et al.   EUROPEAN SPINE JOURNAL

TRPC6 expression in neurons is differentially regulated by NR2A- and NR2B-containing NMDA receptors

(2017) Zhongwei Qu et al.   JOURNAL OF NEUROCHEMISTRY

TRPV1 channels are critical brain inflammation detectors and neuropathic pain biomarkers in mice

(2017) Maria Cristina Marrone et al.   Nature Communications

TRPV1 and TRPA1 in cutaneous neurogenic and chronic inflammation: pro-inflammatory response induced by their activation and their sensitization

(2017) Olivier Gouin et al.   Protein & Cell

Toll-like Receptor Activation Induces Degeneration of Human Intervertebral Discs

(2017) Emerson Krock et al.   Scientific Reports

Molecular mechanisms of biological aging in intervertebral discs

(2016) Nam V. Vo et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats

(2016) Sonya G Lehto et al.   Molecular Pain

Challenges to develop novel anti-inflammatory and analgesic drugs

(2016) Bálint Botz et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Membrane channel gene expression in human costal and articular chondrocytes

(2016) A. Asmar et al.   Organogenesis

Systemic desensitization through TRPA1 channels by capsazepine and mustard oil - a novel strategy against inflammation and pain

(2016) Katrin Kistner et al.   Scientific Reports

Increased excitability of medium-sized dorsal root ganglion neurons by prolonged interleukin-1β exposure is K+channel dependent and reversible

(2015) Patrick L. Stemkowski et al.   JOURNAL OF PHYSIOLOGY-LONDON

TRPA1 as a drug target—promise and challenges

(2015) Jun Chen et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

RNA-Seq Analysis of Human Trigeminal and Dorsal Root Ganglia with a Focus on Chemoreceptors

(2015) Caroline Flegel et al.   PLoS One

Contribution of TRPC3 to Store-Operated Calcium Entry and Inflammatory Transductions in Primary Nociceptors

(2014) Hazim Alkhani et al.   Molecular Pain

Upregulation of the Transient Receptor Potential Ankyrin 1 Ion Channel in the Inflamed Human and Mouse Colon and Its Protective Roles

(2014) József Kun et al.   PLoS One

Chronic Hypoxia Increases TRPC6 Expression and Basal Intracellular Ca2+ Concentration in Rat Distal Pulmonary Venous Smooth Muscle

(2014) Lei Xu et al.   PLoS One

Increase of nerve growth factor levels in the human herniated intervertebral disc: can annular rupture trigger discogenic back pain?

(2014) Yasuchika Aoki et al.   ARTHRITIS RESEARCH & THERAPY

Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain

(2013) S Kelly et al.   ANNALS OF THE RHEUMATIC DISEASES

Role of proinflammatory cytokines on expression of vitamin D metabolism and target genes in colon cancer cells

(2013) Doris M. Hummel et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Crucial Role of TRPC1 and TRPC4 in Cystitis-Induced Neuronal Sprouting and Bladder Overactivity

(2013) Mathieu Boudes et al.   PLoS One

TRPM8 activation attenuates inflammatory responses in mouse models of colitis

(2013) R. Ramachandran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substance P Stimulates Production of Inflammatory Cytokines in Human Disc Cells

(2013) Christopher K. Kepler et al.   SPINE

The functions of TRPA1 and TRPV1: moving away from sensory nerves

(2012) ES Fernandes et al.   BRITISH JOURNAL OF PHARMACOLOGY

TRPM2 Contributes to Inflammatory and Neuropathic Pain through the Aggravation of Pronociceptive Inflammatory Responses in Mice

(2012) K. Haraguchi et al.   JOURNAL OF NEUROSCIENCE

The Capsaicin Receptor TRPV1 Is a Crucial Mediator of the Noxious Effects of Mustard Oil

(2011) Wouter Everaerts et al.   CURRENT BIOLOGY

The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity

(2010) Keith Brew et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

International Union of Basic and Clinical Pharmacology. LXXVI. Current Progress in the Mammalian TRP Ion Channel Family

(2010) L.-J. Wu et al.   PHARMACOLOGICAL REVIEWS

The Role of Transient Receptor Potential Cation Channels in Ca2+ Signaling

(2010) M. Gees et al.   Cold Spring Harbor Perspectives in Biology

Transient Receptor Potential Channels in Pain and Inflammation: Therapeutic Opportunities

(2010) Mark A. Schumacher   Pain Practice

Matrix Remodeling During Intervertebral Disc Growth and Degeneration Detected by Multichromatic FAST Staining

(2008) Victor Y.L. Leung et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

TRPV2 Is Activated by Cannabidiol and Mediates CGRP Release in Cultured Rat Dorsal Root Ganglion Neurons

(2008) N. Qin et al.   JOURNAL OF NEUROSCIENCE

Expression of ion channels of the TRP family in articular chondrocytes from osteoarthritic patients: changes between native and in vitro propagated chondrocytes

(2008) K. Gavenis et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Role of TRPV1 in Different Subtypes of Dorsal Root Ganglion Neurons in Rat Chronic Inflammatory Nociception Induced by Complete Freund's Adjuvant

(2008) Lu Yu et al.   Molecular Pain

Transient receptor potential channels: targeting pain at the source

(2008) Ardem Patapoutian et al.   NATURE REVIEWS DRUG DISCOVERY