The Dual-Specificity Phosphatase 10 (DUSP10): Its Role in Cancer, Inflammation, and Immunity

miRNA-7a-2-3p Inhibits Neuronal Apoptosis in Oxygen-Glucose Deprivation (OGD) Model

(2019) Zi-Bin Zhang et al.   Frontiers in Neuroscience

Effects of interactions between common genetic variants and alcohol consumption on colorectal cancer risk

(2018) Nan Song et al.   Oncotarget

Colorectal Cancer-Associated Genes Are Associated with Tooth Agenesis and May Have a Role in Tooth Development

(2018) Meredith A. Williams et al.   Scientific Reports

MicroRNA-92a Drives Th1 Responses in the Experimental Autoimmune Encephalomyelitis

(2018) Nahid Rezaei et al.   INFLAMMATION

DUSP10 Negatively Regulates the Inflammatory Response to Rhinovirus through Interleukin-1β Signaling

(2018) Grace C. A. Manley et al.   JOURNAL OF VIROLOGY

GTRD: a database on gene transcription regulation—2019 update

(2018) Ivan Yevshin et al.   NUCLEIC ACIDS RESEARCH

DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells

(2018) Takeshi Yamamoto et al.   Nature Communications

Andrographolide inhibits hypoxia-induced hypoxia-inducible factor 1α and endothelin 1 expression through the heme oxygenase 1/CO/cGMP/MKP-5 pathways in EA.hy926 cells

(2017) Hung-Chih Lin et al.   ENVIRONMENTAL TOXICOLOGY

Nepetoidin B, a Natural Product, Inhibits LPS-stimulated Nitric Oxide Production via Modulation of iNOS Mediated by NF-κB/MKP-5 Pathways

(2017) Xiaxia Wu et al.   PHYTOTHERAPY RESEARCH

A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis

(2017) Ajay Mishra et al.   eLife

The extended human PTPome: a growing tyrosine phosphatase family

(2016) Andrés Alonso et al.   FEBS Journal

p38MAPK activation and DUSP10 expression in meningiomas

(2016) Mahlon D. Johnson et al.   JOURNAL OF CLINICAL NEUROSCIENCE

High molecular weight hyaluronic acid regulates MMP13 expression in chondrocytes via DUSP10/MKP5

(2016) Junya Furuta et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation

(2016) Xin Liu et al.   Nature Communications

Regulation of Inflammatory Cytokine Production by MKP-5 in Macrophages

(2015) Tuija Hömmö et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Regulation of Adipose Tissue Inflammation and Insulin Resistance by MAPK Phosphatase 5

(2015) Yongliang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dissecting high from low responders in a vitamin D3 intervention study

(2015) Noora Saksa et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

AGR2 oncoprotein inhibits p38 MAPK and p53 activation through a DUSP10-mediated regulatory pathway

(2015) Roman Hrstka et al.   Molecular Oncology

DUSP10 regulates intestinal epithelial cell growth and colorectal tumorigenesis

(2015) C W Png et al.   ONCOGENE

MAPK Phosphatase 5 Expression Induced by Influenza and Other RNA Virus Infection Negatively Regulates IRF3 Activation and Type I Interferon Response

(2015) Sharmy J. James et al.   Cell Reports

Relevance of Vitamin D Receptor Target Genes for Monitoring the Vitamin D Responsiveness of Primary Human Cells

(2015) Maja Vukić et al.   PLoS One

Microarray phosphatome profiling of breast cancer patients unveils a complex phosphatase regulatory role of the MAPK and PI3K pathways in estrogen receptor-negative breast cancers

(2014) RAMON G. MANZANO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

MAPK Phosphotase 5 Deficiency Contributes to Protection against Blood-Stage Plasmodium yoelii 17XL Infection in Mice

(2014) Q. Cheng et al.   JOURNAL OF IMMUNOLOGY

Dual-Specificity Phosphatases as Molecular Targets for Inhibition in Human Disease

(2013) Pablo Ríos et al.   ANTIOXIDANTS & REDOX SIGNALING

miR-92a/DUSP10/JNK signalling axis promotes human pancreatic cancer cells proliferation

(2013) Gengsheng He et al.   BIOMEDICINE & PHARMACOTHERAPY

Type 2 cGMP-dependent protein kinase regulates homeostasis by blocking c-Jun N-terminal kinase in the colon epithelium

(2013) R Wang et al.   CELL DEATH AND DIFFERENTIATION

DUSP10 gene polymorphism and risk of colorectal cancer in the Han Chinese population

(2013) Tao Zhang et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

Improved regenerative myogenesis and muscular dystrophy in mice lacking Mkp5

(2013) Hao Shi et al.   JOURNAL OF CLINICAL INVESTIGATION

Deregulation of protein phosphatase expression in acute myeloid leukemia

(2013) Nuzhat N. Kabir et al.   MEDICAL ONCOLOGY

Role for Prdx1 as a specific sensor in redox-regulated senescence in breast cancer

(2013) B Turner-Ivey et al.   ONCOGENE

Polycyclic aromatic hydrocarbon (PAH)-mediated upregulation of hepatic microRNA-181 family promotes cancer cell migration by targeting MAPK phosphatase-5, regulating the activation of p38 MAPK

(2013) Mi-Kyung Song et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Map kinase phosphatase 5 protects against sepsis-induced acute lung injury

(2012) Feng Qian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Expression of protein-tyrosine phosphatases in Acute Myeloid Leukemia cells: FLT3 ITD sustains high levels of DUSP6 expression

(2012) Deepika Arora et al.   Cell Communication and Signaling

An essential function for MKP5 in the formation of oxidized low density lipid-induced foam cells

(2012) Li-Jun Luo et al.   CELLULAR SIGNALLING

Dual specificity phosphatases 10 and 16 are positive regulators of EGF-stimulated ERK activity: Indirect regulation of ERK signals by JNK/p38 selective MAPK phosphatases

(2012) Ann R. Finch et al.   CELLULAR SIGNALLING

Induction of antigen-specific human T suppressor cells by membrane and soluble ILT3

(2012) George Vlad et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

p53 Binding Prevents Phosphatase-mediated Inactivation of Diphosphorylated c-Jun N-terminal Kinase

(2012) Pramod S. Gowda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Department of ENT, Nanfang Hospital, Southern Medical University, Guangzhou 510515, P.R. China

(2012) Hiroshi Shima   ONCOLOGY REPORTS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The NLR Adaptor ASC/PYCARD Regulates DUSP10, Mitogen-activated Protein Kinase (MAPK), and Chemokine Induction Independent of the Inflammasome

(2011) Debra J. Taxman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Three-Dimensional Docking in the MAPK p38 

(2011) E. J. Goldsmith   Science Signaling

A Distinct Interaction Mode Revealed by the Crystal Structure of the Kinase p38  with the MAPK Binding Domain of the Phosphatase MKP5

(2011) Y.-Y. Zhang et al.   Science Signaling

Global Transcriptional Response of Macrophage-Like THP-1 Cells to Shiga Toxin Type 1

(2010) D. Leyva-Illades et al.   INFECTION AND IMMUNITY

A non-redundant role for MKP5 in limiting ROS production and preventing LPS-induced vascular injury

(2009) Feng Qian et al.   EMBO JOURNAL

Convergent Functional Genomics of Oligodendrocyte Differentiation Identifies Multiple Autoinhibitory Signaling Circuits

(2009) R. Pescini Gobert et al.   MOLECULAR AND CELLULAR BIOLOGY

Dual-specificity MAP kinase phosphatases (MKPs) and cancer

(2008) Stephen M. Keyse   CANCER AND METASTASIS REVIEWS

Dual-specificity phosphatases in the hypo-osmotic stress response of keratin-defective epithelial cell lines

(2008) Mirjana Liovic et al.   EXPERIMENTAL CELL RESEARCH

Enzymatic Activity and Substrate Specificity of Mitogen-activated Protein Kinase p38α in Different Phosphorylation States

(2008) Yuan-Yuan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucocorticoids Inhibit IRF3 Phosphorylation in Response to Toll-like Receptor-3 and -4 by Targeting TBK1 Activation

(2008) Claire E. McCoy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY