Evaluating the effects of switching from cigarette smoking to using a heated tobacco product on health effect indicators in healthy subjects: study protocol for a randomized controlled trial

Carbonyl emissions from a novel heated tobacco product (IQOS): comparison with an e-cigarette and a tobacco cigarette

(2018) Konstantinos E. Farsalinos et al.   ADDICTION

Levels of selected analytes in the emissions of “heat not burn” tobacco products that are relevant to assess human health risks

(2018) Nadja Mallock et al.   ARCHIVES OF TOXICOLOGY

A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. I. Inhalation exposure, clinical pathology and histopathology

(2018) Blaine W. Phillips et al.   FOOD AND CHEMICAL TOXICOLOGY

OUP accepted manuscript

(2018)   NICOTINE & TOBACCO RESEARCH

Suitability of biomarkers of biological effects (BOBEs) for assessing the likelihood of reducing the tobacco related disease risk by new and innovative tobacco products: A literature review

(2018) Gerhard Scherer   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Assessment of novel tobacco heating product THP1.0. Part 6: A comparative in vitro study using contemporary screening approaches

(2018) Mark Taylor et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Assessment of tobacco heating product THP1.0. Part 1: Series introduction

(2018) Christopher Proctor   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Assessment of tobacco heating product THP1.0. Part 9: The placement of a range of next-generation products on an emissions continuum relative to cigarettes via pre-clinical assessment studies

(2018) James Murphy et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Assessment of tobacco heating product THP1.0. Part 2: Product design, operation and thermophysical characterisation

(2018) Dan Eaton et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Assessment of novel tobacco heating product THP1.0. Part 3: Comprehensive chemical characterisation of harmful and potentially harmful aerosol emissions

(2018) Mark Forster et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Vascular endothelial function is impaired by aerosol from a single IQOS HeatStick to the same extent as by cigarette smoke

(2018) Pooneh Nabavizadeh et al.   TOBACCO CONTROL

A novel hybrid tobacco product that delivers a tobacco flavour note with vapour aerosol (Part 2): In vitro biological assessment and comparison with different tobacco-heating products

(2017) Damien Breheny et al.   FOOD AND CHEMICAL TOXICOLOGY

Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day repeated exposure study

(2017) Filippo Zanetti et al.   FOOD AND CHEMICAL TOXICOLOGY

Arterial stiffness as a risk factor for clinical hypertension

(2017) Michel E. Safar   Nature Reviews Cardiology

Nicotine Delivery to the Aerosol of a Heat-Not-Burn Tobacco Product: Comparison With a Tobacco Cigarette and E-Cigarettes

(2017) Konstantinos E Farsalinos et al.   NICOTINE & TOBACCO RESEARCH

Comparative assessment of HPHC yields in the Tobacco Heating System THS2.2 and commercial cigarettes

(2017) G. Jaccard et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Assessing modified risk tobacco and nicotine products: Description of the scientific framework and assessment of a closed modular electronic cigarette

(2017) James Murphy et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

The effect of age on the relationship between cardiac and vascular function

(2016) David Houghton et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Evaluation of the Tobacco Heating System 2.2. Part 6: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of a mentholated version compared with mentholated and non-mentholated cigarette smoke

(2016) Alberto Oviedo et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Evaluation of the Tobacco Heating System 2.2 (THS2.2). Part 5: microRNA expression from a 90-day rat inhalation study indicates that exposure to THS2.2 aerosol causes reduced effects on lung tissue compared with cigarette smoke

(2016) Alain Sewer et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Evaluation of the Tobacco Heating System 2.2. Part 2: Chemical composition, genotoxicity, cytotoxicity, and physical properties of the aerosol

(2016) Jean-Pierre Schaller et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Changes in levels of biomarkers of exposure and biological effect in a controlled study of smokers switched from conventional cigarettes to reduced-toxicant-prototype cigarettes

(2015) Christopher J. Shepperd et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

A correlation study applied to biomarkers of internal and effective dose for acrylonitrile and 4-aminobiphenyl in smokers

(2014) Gerhard Scherer et al.   BIOMARKERS

Comparison of dermal tumor promotion activity of cigarette smoke condensate from prototype (heated) cigarette and reference (combusted) cigarette in SENCAR mice

(2014) Hiroyuki Tsuji et al.   FOOD AND CHEMICAL TOXICOLOGY

The effect on health of switching from cigarettes to snus – A review

(2013) Peter N. Lee   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Oxidative stress and endothelial dysfunction: Clinical evidence and therapeutic implications

(2013) Yukihito Higashi et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Determination of Nicotine Absorption from Multiple Tobacco Products and Nicotine Gum

(2012) H. Digard et al.   NICOTINE & TOBACCO RESEARCH

The Fagerstrom Test for Nicotine Dependence as a Predictor of Smoking Abstinence: A Pooled Analysis of Varenicline Clinical Trial Data

(2012) K. Fagerstrom et al.   NICOTINE & TOBACCO RESEARCH

Reduced exposure evaluation of an Electrically Heated Cigarette Smoking System. Part 7: A one-month, randomized, ambulatory, controlled clinical study in Poland

(2012) Claire Martin Leroy et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Treatment of nicotine addiction: present therapeutic options and pipeline developments

(2011) Riccardo Polosa et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Early Improvement in Peripheral Vascular Tone following Smoking Cessation Using Nicotine Replacement Therapy: Aortic Wave Reflection Analysis

(2010) Antoine Roux et al.   CARDIOLOGY