Intracellular parasitism, the driving force of evolution of Legionella pneumophila and the genus Legionella

More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells

(2019) Laura Gomez-Valero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dot/Icm-Translocated Proteins Important for Biogenesis of the Coxiella burnetii -Containing Vacuole Identified by Screening of an Effector Mutant Sublibrary

(2018) Emerson Crabill et al.   INFECTION AND IMMUNITY

Environmental adaptation of Acanthamoeba castellanii and Entamoeba histolytica at genome level as seen by comparative genomic analysis

(2018) Victoria Shabardina et al.   International Journal of Biological Sciences

Identification and characterization of a large family of superbinding bacterial SH2 domains

(2018) Tomonori Kaneko et al.   Nature Communications

Lateral gene transfer of p -cresol- and indole-producing enzymes from environmental bacteria to M astigamoeba balamuthi

(2017) Eva Nývltová et al.   ENVIRONMENTAL MICROBIOLOGY

Comparative Genomic Analysis of Acanthamoeba Endosymbionts Highlights the Role of Amoebae as a “Melting Pot” Shaping the Rickettsiales Evolution

(2017) Zhang Wang et al.   Genome Biology and Evolution

Legionella and Coxiella effectors: strength in diversity and activity

(2017) Jiazhang Qiu et al.   NATURE REVIEWS MICROBIOLOGY

Structures and kinetics for plant nucleoside triphosphate diphosphohydrolases support a domain motion catalytic mechanism

(2017) Emma L. Summers et al.   PROTEIN SCIENCE

Formation of the Legionella Replicative Compartment at the Crossroads of Retrograde Trafficking

(2017) Kevin Bärlocher et al.   Frontiers in Cellular and Infection Microbiology

Legionella pneumophilarestrains autophagy by modulating the host's sphingolipid metabolism

(2016) Monica Rolando et al.   Autophagy

Legionella pneumophila, armed to the hilt: justifying the largest arsenal of effectors in the bacterial world

(2016) Alexander W Ensminger   CURRENT OPINION IN MICROBIOLOGY

Genomic analysis of 38 Legionella species identifies large and diverse effector repertoires

(2016) David Burstein et al.   NATURE GENETICS

Legionella pneumophilaS1P-lyase targets host sphingolipid metabolism and restrains autophagy

(2016) Monica Rolando et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting of host organelles by pathogenic bacteria: a sophisticated subversion strategy

(2015) Pedro Escoll et al.   NATURE REVIEWS MICROBIOLOGY

Multiple ecto-nucleoside triphosphate diphosphohydrolases facilitate intracellular replication ofLegionella pneumophila

(2014) Patrice Riedmaier et al.   BIOCHEMICAL JOURNAL

Legionella pneumophila type IV effectors hijack the transcription and translation machinery of the host cell

(2014) Monica Rolando et al.   TRENDS IN CELL BIOLOGY

Legionella pneumophila Effector RomA Uniquely Modifies Host Chromatin to Repress Gene Expression and Promote Intracellular Bacterial Replication

(2013) Monica Rolando et al.   Cell Host & Microbe

Computational modeling and experimental validation of the Legionella and Coxiella virulence-related type-IVB secretion signal

(2013) Z. Lifshitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome Dynamics in Legionella: The Basis of Versatility and Adaptation to Intracellular Replication

(2013) L. Gomez-Valero et al.   Cold Spring Harbor Perspectives in Medicine

Post-translational modifications of host proteins byLegionella pneumophila: a sophisticated survival strategy

(2012) Monica Rolando et al.   Future Microbiology

The Legionella Effector RavZ Inhibits Host Autophagy Through Irreversible Atg8 Deconjugation

(2012) A. Choy et al.   SCIENCE

Lateral gene exchanges shape the genomes of amoeba-resisting microorganisms

(2012) Claire Bertelli et al.   Frontiers in Cellular and Infection Microbiology

Insight into cross-talk between intra-amoebal pathogens

(2011) Gregory Gimenez et al.   BMC GENOMICS

Extensive recombination events and horizontal gene transfer shaped the Legionella pneumophila genomes

(2011) Laura Gomez-Valero et al.   BMC GENOMICS

Comprehensive Identification of Protein Substrates of the Dot/Icm Type IV Transporter of Legionella pneumophila

(2011) Wenhan Zhu et al.   PLoS One

Minimization of the Legionella pneumophila genome reveals chromosomal regions involved in host range expansion

(2011) T. J. O'Connor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative and Functional Genomics of Legionella Identified Eukaryotic Like Proteins as Key Players in Host?Pathogen Interactions

(2011) Laura Gomez-Valero et al.   Frontiers in Microbiology

Modulation of Host Cell Function byLegionella pneumophilaType IV Effectors

(2010) Andree Hubber et al.   Annual Review of Cell and Developmental Biology

Molecular Pathogenesis of Infections Caused by Legionella pneumophila

(2010) H. J. Newton et al.   CLINICAL MICROBIOLOGY REVIEWS

The origins of eukaryotic-like proteins in Legionella pneumophila

(2010) Mor N. Lurie-Weinberger et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Lipidation by the Host Prenyltransferase Machinery Facilitates Membrane Localization ofLegionella pneumophilaEffector Proteins

(2010) Stanimir S. Ivanov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploitation of conserved eukaryotic host cell farnesylation machinery by an F-box effector ofLegionella pneumophila

(2010) Christopher T.D. Price et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Analysis of the Legionella longbeachae Genome and Transcriptome Uncovers Unique Strategies to Cause Legionnaires' Disease

(2010) Christel Cazalet et al.   PLoS Genetics

ALegionellaeffector acquired from protozoa is involved in sphingolipids metabolism and is targeted to the host cell mitochondria

(2009) Elena Degtyar et al.   CELLULAR MICROBIOLOGY

The Genome of the Amoeba Symbiont "Candidatus Amoebophilus asiaticus" Reveals Common Mechanisms for Host Cell Interaction among Amoeba-Associated Bacteria

(2009) S. Schmitz-Esser et al.   JOURNAL OF BACTERIOLOGY

Horizontal gene transfer in evolution: facts and challenges

(2009) L. Boto   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Molecular Mimicry by an F-Box Effector of Legionella pneumophila Hijacks a Conserved Polyubiquitination Machinery within Macrophages and Protozoa

(2009) Christopher T. Price et al.   PLoS Pathogens

Giant viruses, giant chimeras: The multiple evolutionary histories of Mimivirus genes

(2008) David Moreira et al.   BMC EVOLUTIONARY BIOLOGY

Legionella translocates an E3 ubiquitin ligase that has multiple U-boxes with distinct functions

(2008) Tomoko Kubori et al.   MOLECULAR MICROBIOLOGY

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

(2008) Ralph R. Isberg et al.   NATURE REVIEWS MICROBIOLOGY

Legionella Eukaryotic-Like Type IV Substrates Interfere with Organelle Trafficking

(2008) Karim Suwwan de Felipe et al.   PLoS Pathogens