Three de novo DDX3X variants associated with distinctive brain developmental abnormalities and brain tumor in intellectually disabled females

De novo DDX3X missense variants in males appear viable and contribute to syndromic intellectual disability

(2019) Pantelis Nicola et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Hyperactivity of Rac1-GTPase pathway impairs neuritogenesis of cortical neurons by altering actin dynamics

(2018) Valentina Zamboni et al.   Scientific Reports

Phenotypic expansion in DDX3X - a common cause of intellectual disability in females

(2018) Xia Wang et al.   Annals of Clinical and Translational Neurology

GRIN2B encephalopathy: novel findings on phenotype, variant clustering, functional consequences and treatment aspects

(2017) Konrad Platzer et al.   JOURNAL OF MEDICAL GENETICS

Identification of Intellectual Disability Genes in Female Patients with a Skewed X-Inactivation Pattern

(2016) Nathalie Fieremans et al.   HUMAN MUTATION

DDX3 Modulates Neurite Development via Translationally Activating an RNA Regulon Involved in Rac1 Activation

(2016) H.-H. Chen et al.   JOURNAL OF NEUROSCIENCE

Tumor-suppressor genes that escape from X-inactivation contribute to cancer sex bias

(2016) Andrew Dunford et al.   NATURE GENETICS

Mutations in DDX3X Are a Common Cause of Unexplained Intellectual Disability with Gender-Specific Effects on Wnt Signaling

(2015) Lot Snijders Blok et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Disorders of Microtubule Function in Neurons: Imaging Correlates

(2015) C.A. Mutch et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Cancer-Associated Mutants of RNA Helicase DDX3X Are Defective in RNA-Stimulated ATP Hydrolysis

(2015) Leslie B. Epling et al.   JOURNAL OF MOLECULAR BIOLOGY

DDX3, a potential target for cancer treatment

(2015) Guus Martinus Bol et al.   Molecular Cancer

Rac-GTPases Regulate Microtubule Stability and Axon Growth of Cortical GABAergic Interneurons

(2014) Simona Tivodar et al.   CEREBRAL CORTEX

Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

(2012) Trevor J. Pugh et al.   NATURE

The role of DDX3 in regulating Snail

(2011) Mianen Sun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Human DEAD-box protein 3 has multiple functions in gene regulation and cell cycle control and is a prime target for viral manipulation

(2009) Martina Schröder   BIOCHEMICAL PHARMACOLOGY