Regulation of centromeric heterochromatin in the cell cycle by phosphorylation of histone H3 tyrosine 41

Heterochromatin Protein 1α Mediates Development and Aggressiveness of Neuroendocrine Prostate Cancer

(2018) Xinpei Ci et al.   CANCER RESEARCH

Targeting epigenetics using synthetic lethality in precision medicine

(2018) Ee Sin Chen   CELLULAR AND MOLECULAR LIFE SCIENCES

Epigenetic inheritance mediated by coupling of RNAi and histone H3K9 methylation

(2018) Ruby Yu et al.   NATURE

Biochemical Basis for Distinct Roles of the Heterochromatin Proteins Swi6 and Chp2

(2017) R. Stefan Isaac et al.   JOURNAL OF MOLECULAR BIOLOGY

Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription

(2017) Gloria Jih et al.   NATURE

Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin

(2017) Adam G. Larson et al.   NATURE

Regulation of transcriptional silencing and chromodomain protein localization at centromeric heterochromatin by histone H3 tyrosine 41 phosphorylation in fission yeast

(2017) Bingbing Ren et al.   NUCLEIC ACIDS RESEARCH

Genome-wide mapping of histone H3K9me2 in acute myeloid leukemia reveals large chromosomal domains associated with massive gene silencing and sites of genome instability

(2017) Anna C. Salzberg et al.   PLoS One

Demethylated HSATII DNA and HSATII RNA Foci Sequester PRC1 and MeCP2 into Cancer-Specific Nuclear Bodies

(2017) Lisa L. Hall et al.   Cell Reports

The loading of condensin in the context of chromatin

(2016) Xavier Robellet et al.   CURRENT GENETICS

Are all repeats created equal? Understanding DNA repeats at an individual level

(2016) Jinpu Yang et al.   CURRENT GENETICS

Epigenetic transcriptional memory

(2016) Agustina D’Urso et al.   CURRENT GENETICS

Histone H3K36 trimethylation is essential for multiple silencing mechanisms in fission yeast

(2016) Shota Suzuki et al.   NUCLEIC ACIDS RESEARCH

Synthetic lethal approaches for assessing combinatorial efficacy of chemotherapeutic drugs

(2016) Rebecca A. Jackson et al.   PHARMACOLOGY & THERAPEUTICS

Identification of Multiple Proteins Coupling Transcriptional Gene Silencing to Genome Stability in Arabidopsis thaliana

(2016) Christopher J. Hale et al.   PLoS Genetics

Predicting chemotherapeutic drug combinations through gene network profiling

(2016) Thi Thuy Trang Nguyen et al.   Scientific Reports

Role of chromatin structure modulation by the histone deacetylase inhibitor trichostatin A on the radio-sensitivity of ataxia telangiectasia

(2015) Roberta Meschini et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Epigenetic Regulation of Chromatin States inSchizosaccharomyces pombe

(2015) Robin C. Allshire et al.   Cold Spring Harbor Perspectives in Biology

Sgf73, a subunit of SAGA complex, is required for the assembly of RITS complex in fission yeast

(2015) Xiaolong Deng et al.   Scientific Reports

Fitness Profiling Links Topoisomerase II Regulation of Centromeric Integrity to Doxorubicin Resistance in Fission Yeast

(2015) Thi Thuy Trang Nguyen et al.   Scientific Reports

Aurora Kinase B Regulates Telomerase Activity via a Centromeric RNA in Stem Cells

(2015) Jan-Philipp Mallm et al.   Cell Reports

A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly

(2013) Daniele Canzio et al.   NATURE

Replication Fork Stability Is Essential for the Maintenance of Centromere Integrity in the Absence of Heterochromatin

(2013) Pao-Chen Li et al.   Cell Reports

Elimination of a specific histone H3K14 acetyltransferase complex bypasses the RNAi pathway to regulate pericentric heterochromatin functions

(2011) B. D. Reddy et al.   GENES & DEVELOPMENT

Roles of Fission Yeast Grc3 Protein in Ribosomal RNA Processing and Heterochromatic Gene Silencing

(2011) Erina Kitano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordination of DNA replication and histone modification by the Rik1–Dos2 complex

(2011) Fei Li et al.   NATURE

SUMOylation promotes de novo targeting of HP1α to pericentric heterochromatin

(2011) Christèle Maison et al.   NATURE GENETICS

Aberrant Overexpression of Satellite Repeats in Pancreatic and Other Epithelial Cancers

(2011) D. T. Ting et al.   SCIENCE

A Strand-Specific Burst in Transcription of Pericentric Satellites Is Required for Chromocenter Formation and Early Mouse Development

(2010) Aline.V. Probst et al.   DEVELOPMENTAL CELL

A chromodomain switch mediated by histone H3 Lys 4 acetylation regulates heterochromatin assembly

(2010) B. Xhemalce et al.   GENES & DEVELOPMENT

Transcriptional Scaffolds for Heterochromatin Assembly

(2009) Hugh P. Cam et al.   CELL

Satellite DNA Spatial Localization and Transcriptional Activity in Mouse Embryonic E-14 and IOUD2 Stem Cells

(2009) N.I. Enukashvily et al.   CYTOGENETIC AND GENOME RESEARCH

JAK2 phosphorylates histone H3Y41 and excludes HP1α from chromatin

(2009) Mark A. Dawson et al.   NATURE

Mechanisms of Polycomb gene silencing: knowns and unknowns

(2009) Jeffrey A. Simon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A transcriptomic analysis of human centromeric and pericentric sequences in normal and tumor cells

(2009) Angéline Eymery et al.   NUCLEIC ACIDS RESEARCH

RNA Interference Guides Histone Modification during the S Phase of Chromosomal Replication

(2008) Anna Kloc et al.   CURRENT BIOLOGY

Chp1-Tas3 Interaction Is Required To Recruit RITS to Fission Yeast Centromeres and for Maintenance of Centromeric Heterochromatin

(2008) J. L. DeBeauchamp et al.   MOLECULAR AND CELLULAR BIOLOGY

Balance between Distinct HP1 Family Proteins Controls Heterochromatin Assembly in Fission Yeast

(2008) M. Sadaie et al.   MOLECULAR AND CELLULAR BIOLOGY

HP1 Proteins Form Distinct Complexes and Mediate Heterochromatic Gene Silencing by Nonoverlapping Mechanisms

(2008) Mohammad R. Motamedi et al.   MOLECULAR CELL

Cell cycle control of centromeric repeat transcription and heterochromatin assembly

(2008) Ee Sin Chen et al.   NATURE

Roles of the Clr4 methyltransferase complex in nucleation, spreading and maintenance of heterochromatin

(2008) Ke Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Splicing Factors Facilitate RNAi-Directed Silencing in Fission Yeast

(2008) E. H. Bayne et al.   SCIENCE